Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | D160Y | Missense | 2 |
| COAD | Colon adenocarcinoma | R322C | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E232Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E404D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E506D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E634* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E673Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E700Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E759D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G344E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K551N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L238L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L90V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | N424K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P268T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P299S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q335* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R558R | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S466F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V189G | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V399V | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Y135C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y40Y | Silent | 1 |
| BRCA | Breast invasive carcinoma | G595G | Silent | 1 |
| BRCA | Breast invasive carcinoma | N748S | Missense | 1 |
| BRCA | Breast invasive carcinoma | P230P | Silent | 1 |
| CESC | Cervical and endocervical cancers | G199E | Missense | 1 |
| CESC | Cervical and endocervical cancers | P98S | Missense | 1 |
| COAD | Colon adenocarcinoma | A369T | Missense | 1 |
| COAD | Colon adenocarcinoma | D501E | Missense | 1 |
| COAD | Colon adenocarcinoma | H667Y | Missense | 1 |
| COAD | Colon adenocarcinoma | P430S | Missense | 1 |
| COAD | Colon adenocarcinoma | R528L | Missense | 1 |
| COAD | Colon adenocarcinoma | S482G | Missense | 1 |
| ESCA | Esophageal carcinoma | S694F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E685* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L38L | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | M142V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V85A | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A416A | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | E447D | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | N60K | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P545P | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S679* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | L676I | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R701C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V435I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P579P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | S793* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | V465A | Missense | 1 |
| LUAD | Lung adenocarcinoma | E140K | Missense | 1 |
| LUAD | Lung adenocarcinoma | L238F | Missense | 1 |
| LUAD | Lung adenocarcinoma | P46L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R100L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R128T | Missense | 1 |
| LUAD | Lung adenocarcinoma | S179A | Missense | 1 |
| LUAD | Lung adenocarcinoma | T287T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L657L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | P260P | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | D160N | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | I717L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R317C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R528P | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | V279I | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | Y644Y | Silent | 1 |
| PRAD | Prostate adenocarcinoma | R580H | Missense | 1 |
| READ | Rectum adenocarcinoma | T761A | Missense | 1 |
| SARC | Sarcoma | S775N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E759K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G663G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L205L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | N16I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P241L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P302L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P315S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S783S | Silent | 1 |
| STAD | Stomach adenocarcinoma | A567V | Missense | 1 |
| STAD | Stomach adenocarcinoma | E700D | Missense | 1 |
| STAD | Stomach adenocarcinoma | H242R | Missense | 1 |
| STAD | Stomach adenocarcinoma | L20L | Silent | 1 |
| STAD | Stomach adenocarcinoma | P393H | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q94* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R328H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R409L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R648Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R739Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S476L | Missense | 1 |
| STAD | Stomach adenocarcinoma | S490C | Missense | 1 |
| STAD | Stomach adenocarcinoma | S694Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | T620R | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | V103L | Missense | 1 |
| THYM | Thymoma | C141S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C141C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G722R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q94Q | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R580H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y153H | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 20 | 20.5 | 33.3 |
| BRCA | Breast invasive carcinoma | 976 | 10 | 1.4 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.7 | 0 |
| COAD | Colon adenocarcinoma | 367 | 0 | 13.7 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 1.4 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 5 | 0 | 16.7 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.7 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 10 | 2.7 | 16.7 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 4.1 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 5 | 1.4 | 16.7 |
| LUAD | Lung adenocarcinoma | 533 | 5 | 8.2 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 10 | 0 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 5.5 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 5 | 1.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.4 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.4 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.4 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 15 | 6.8 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 5 | 16.4 | 16.7 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.4 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 1.4 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 10 | 4.1 | 0 |