Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| STAD | Stomach adenocarcinoma | G225C | Missense | 22 |
| COAD | Colon adenocarcinoma | I364V | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A314A | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | D868N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E648K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E87Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L611L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q1044* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R137T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R831Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S374L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S533I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S951C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | W901C | Missense | 1 |
| BRCA | Breast invasive carcinoma | A260D | Missense | 1 |
| BRCA | Breast invasive carcinoma | D685N | Missense | 1 |
| BRCA | Breast invasive carcinoma | E153K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E905K | Missense | 1 |
| BRCA | Breast invasive carcinoma | P1101R | Missense | 1 |
| CESC | Cervical and endocervical cancers | E1040Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | M32I | Missense | 1 |
| CESC | Cervical and endocervical cancers | P386A | Missense | 1 |
| COAD | Colon adenocarcinoma | A531G | Missense | 1 |
| COAD | Colon adenocarcinoma | C972C | Silent | 1 |
| COAD | Colon adenocarcinoma | D739G | Missense | 1 |
| COAD | Colon adenocarcinoma | E1068K | Missense | 1 |
| COAD | Colon adenocarcinoma | E966K | Missense | 1 |
| COAD | Colon adenocarcinoma | E988K | Missense | 1 |
| COAD | Colon adenocarcinoma | H133Q | Missense | 1 |
| COAD | Colon adenocarcinoma | I364T | Missense | 1 |
| COAD | Colon adenocarcinoma | L993L | Silent | 1 |
| COAD | Colon adenocarcinoma | R1163H | Missense | 1 |
| COAD | Colon adenocarcinoma | R186H | Missense | 1 |
| COAD | Colon adenocarcinoma | S608P | Missense | 1 |
| COAD | Colon adenocarcinoma | T814T | Silent | 1 |
| ESCA | Esophageal carcinoma | G1160R | Missense | 1 |
| ESCA | Esophageal carcinoma | S694* | Nonsense | 1 |
| GBM | Glioblastoma multiforme | E1042K | Missense | 1 |
| GBM | Glioblastoma multiforme | R1155K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D418G | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D738N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1020Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E507K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E594K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I363T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L1174P | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P48P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P512L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R767* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V736G | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E914E | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | L234Q | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P1131P | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | S694L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | T286T | Silent | 1 |
| LGG | Brain Lower Grade Glioma | M400V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E1042G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I364I | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | K1215R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L1080S | Missense | 1 |
| LUAD | Lung adenocarcinoma | E863Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | F1124F | Silent | 1 |
| LUAD | Lung adenocarcinoma | G346W | Missense | 1 |
| LUAD | Lung adenocarcinoma | I419M | Missense | 1 |
| LUAD | Lung adenocarcinoma | L1106L | Silent | 1 |
| LUAD | Lung adenocarcinoma | P580P | Silent | 1 |
| LUAD | Lung adenocarcinoma | P907S | Missense | 1 |
| LUAD | Lung adenocarcinoma | P917R | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q707Q | Silent | 1 |
| LUAD | Lung adenocarcinoma | R1163H | Missense | 1 |
| LUAD | Lung adenocarcinoma | R767L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R831Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | R884S | Missense | 1 |
| LUAD | Lung adenocarcinoma | V215V | Silent | 1 |
| LUAD | Lung adenocarcinoma | V345V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | A166A | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | D412H | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | I364F | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | V698F | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | V847L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G1067G | Silent | 1 |
| READ | Rectum adenocarcinoma | D876Y | Missense | 1 |
| READ | Rectum adenocarcinoma | E920* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | V529A | Missense | 1 |
| SARC | Sarcoma | D356E | Missense | 1 |
| SARC | Sarcoma | G1160V | Missense | 1 |
| SARC | Sarcoma | S268F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A626G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E999E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G1222E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G1222R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H873Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K1117K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L473L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1065S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P458S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P592L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P596L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P663L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q1167Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Q306Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1090F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1090S | Silent | 1 |
| STAD | Stomach adenocarcinoma | C1029C | Silent | 1 |
| STAD | Stomach adenocarcinoma | E409D | Missense | 1 |
| STAD | Stomach adenocarcinoma | E952K | Missense | 1 |
| STAD | Stomach adenocarcinoma | P300L | Missense | 1 |
| STAD | Stomach adenocarcinoma | P751H | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q1044* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | Q679H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1163H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R54H | Missense | 1 |
| STAD | Stomach adenocarcinoma | V480A | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | S29Y | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | T279T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A770T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E393* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E704* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E822K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E988K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E999K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H1105N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1155I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R774H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R802* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R82* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1026S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1038N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S690G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T1089I | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 3.6 | 7.8 | 11.1 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 4.3 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.6 | 0 |
| COAD | Colon adenocarcinoma | 367 | 10.7 | 10.3 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0.9 | 11.1 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.7 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.6 | 7.8 | 11.1 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 10.7 | 1.7 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0.9 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.6 | 2.6 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 21.4 | 7.8 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 3.6 | 0.9 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.6 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 3.6 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.7 | 11.1 |
| SARC | Sarcoma | 247 | 0 | 2.6 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 21.4 | 8.6 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 3.6 | 25.9 | 11.1 |
| TGCT | Testicular Germ Cell Tumors | 147 | 3.6 | 0.9 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 10.7 | 8.6 | 44.4 |