Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | A232A | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | D347H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D400N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E558D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I229I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | M237I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R545W | Missense | 1 |
| BRCA | Breast invasive carcinoma | D441D | Silent | 1 |
| BRCA | Breast invasive carcinoma | D481D | Silent | 1 |
| BRCA | Breast invasive carcinoma | E488E | Silent | 1 |
| BRCA | Breast invasive carcinoma | L524L | Silent | 1 |
| BRCA | Breast invasive carcinoma | Q561L | Missense | 1 |
| BRCA | Breast invasive carcinoma | Y51Y | Silent | 1 |
| CESC | Cervical and endocervical cancers | R311W | Missense | 1 |
| COAD | Colon adenocarcinoma | A295T | Missense | 1 |
| COAD | Colon adenocarcinoma | A595V | Missense | 1 |
| COAD | Colon adenocarcinoma | D442D | Silent | 1 |
| COAD | Colon adenocarcinoma | E343K | Missense | 1 |
| COAD | Colon adenocarcinoma | H580H | Silent | 1 |
| COAD | Colon adenocarcinoma | L290V | Missense | 1 |
| COAD | Colon adenocarcinoma | S391S | Silent | 1 |
| COAD | Colon adenocarcinoma | T291M | Missense | 1 |
| ESCA | Esophageal carcinoma | D441E | Missense | 1 |
| ESCA | Esophageal carcinoma | L145L | Silent | 1 |
| ESCA | Esophageal carcinoma | Q426H | Missense | 1 |
| ESCA | Esophageal carcinoma | V299M | Missense | 1 |
| ESCA | Esophageal carcinoma | V419M | Missense | 1 |
| GBM | Glioblastoma multiforme | D533E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D292N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E405Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G332G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M237I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R569C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S391L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S391S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S396* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S491S | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | E574E | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | P23P | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | T291T | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | T579T | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | D400V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | D82E | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I229F | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q575R | Missense | 1 |
| LUAD | Lung adenocarcinoma | A295T | Missense | 1 |
| LUAD | Lung adenocarcinoma | E540D | Missense | 1 |
| LUAD | Lung adenocarcinoma | G330E | Missense | 1 |
| LUAD | Lung adenocarcinoma | G414* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | G414V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G449G | Silent | 1 |
| LUAD | Lung adenocarcinoma | G543D | Missense | 1 |
| LUAD | Lung adenocarcinoma | R541C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S483S | Silent | 1 |
| LUAD | Lung adenocarcinoma | T417T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | D167Y | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R545W | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V419V | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | R311R | Silent | 1 |
| PRAD | Prostate adenocarcinoma | P157S | Missense | 1 |
| READ | Rectum adenocarcinoma | T166T | Silent | 1 |
| SARC | Sarcoma | T220T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E514G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F148F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G172R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G543G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I447I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L383F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L443L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L522L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P466S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P546S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S293S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S384S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S552F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S557T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T455T | Silent | 1 |
| STAD | Stomach adenocarcinoma | D560D | Silent | 1 |
| STAD | Stomach adenocarcinoma | G320G | Silent | 1 |
| STAD | Stomach adenocarcinoma | R316W | Missense | 1 |
| STAD | Stomach adenocarcinoma | T291M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V338M | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | D308E | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | P517H | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | T291K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A592A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D167G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D441D | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L456I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P120L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S358L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S391S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T369T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T527M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 5.1 | 9.4 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 12.8 | 1.9 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.9 | 0 |
| COAD | Colon adenocarcinoma | 367 | 7.7 | 9.4 | 0 |
| ESCA | Esophageal carcinoma | 185 | 2.6 | 7.5 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.9 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 7.7 | 9.4 | 50 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 10.3 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 7.5 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 7.7 | 11.3 | 50 |
| LUSC | Lung squamous cell carcinoma | 177 | 2.6 | 3.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2.6 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.9 | 0 |
| READ | Rectum adenocarcinoma | 122 | 2.6 | 0 | 0 |
| SARC | Sarcoma | 247 | 2.6 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 20.5 | 13.2 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 5.1 | 5.7 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 5.7 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 10.3 | 9.4 | 0 |