Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | E408K | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | P182S | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | S821F | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E282* | Nonsense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E462* | Nonsense | 2 |
| BLCA | Bladder urothelial carcinoma | D680Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E137Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E282* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E502D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E504K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G886E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H734Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I146I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | I522R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L607R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P178T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q935* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R54C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S896* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | D355N | Missense | 1 |
| BRCA | Breast invasive carcinoma | E453G | Missense | 1 |
| BRCA | Breast invasive carcinoma | G398D | Missense | 1 |
| BRCA | Breast invasive carcinoma | P542R | Missense | 1 |
| BRCA | Breast invasive carcinoma | V211V | Silent | 1 |
| CESC | Cervical and endocervical cancers | A204V | Missense | 1 |
| CESC | Cervical and endocervical cancers | S196L | Missense | 1 |
| CESC | Cervical and endocervical cancers | S816L | Missense | 1 |
| COAD | Colon adenocarcinoma | A89A | Silent | 1 |
| COAD | Colon adenocarcinoma | A89T | Missense | 1 |
| COAD | Colon adenocarcinoma | E176* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | E469K | Missense | 1 |
| COAD | Colon adenocarcinoma | F369F | Silent | 1 |
| COAD | Colon adenocarcinoma | K375N | Missense | 1 |
| COAD | Colon adenocarcinoma | K500T | Missense | 1 |
| COAD | Colon adenocarcinoma | L83V | Missense | 1 |
| COAD | Colon adenocarcinoma | P682L | Missense | 1 |
| COAD | Colon adenocarcinoma | R618C | Missense | 1 |
| COAD | Colon adenocarcinoma | T620T | Silent | 1 |
| COAD | Colon adenocarcinoma | V312I | Missense | 1 |
| ESCA | Esophageal carcinoma | A832T | Missense | 1 |
| ESCA | Esophageal carcinoma | K848M | Missense | 1 |
| ESCA | Esophageal carcinoma | V56V | Silent | 1 |
| GBM | Glioblastoma multiforme | T371M | Missense | 1 |
| GBM | Glioblastoma multiforme | T940K | Missense | 1 |
| GBM | Glioblastoma multiforme | V312I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A91T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D712G | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L575L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P761P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R422H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S545R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S648* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V420G | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V729I | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E844* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E93* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P377P | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | R841R | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | V240A | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A292T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | C709Y | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S501S | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | D57D | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | S257S | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | V116F | Missense | 1 |
| LUAD | Lung adenocarcinoma | A89V | Missense | 1 |
| LUAD | Lung adenocarcinoma | D300E | Missense | 1 |
| LUAD | Lung adenocarcinoma | D804N | Missense | 1 |
| LUAD | Lung adenocarcinoma | K183R | Missense | 1 |
| LUAD | Lung adenocarcinoma | K265N | Missense | 1 |
| LUAD | Lung adenocarcinoma | K286N | Missense | 1 |
| LUAD | Lung adenocarcinoma | K481M | Missense | 1 |
| LUAD | Lung adenocarcinoma | K908N | Missense | 1 |
| LUAD | Lung adenocarcinoma | L564I | Missense | 1 |
| LUAD | Lung adenocarcinoma | L637L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L744L | Silent | 1 |
| LUAD | Lung adenocarcinoma | N752T | Missense | 1 |
| LUAD | Lung adenocarcinoma | P726T | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q723H | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q748H | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q899K | Missense | 1 |
| LUAD | Lung adenocarcinoma | R492G | Missense | 1 |
| LUAD | Lung adenocarcinoma | R616I | Missense | 1 |
| LUAD | Lung adenocarcinoma | S131C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S166R | Missense | 1 |
| LUAD | Lung adenocarcinoma | S200I | Missense | 1 |
| LUAD | Lung adenocarcinoma | S715T | Missense | 1 |
| LUAD | Lung adenocarcinoma | T371T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | A204A | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | F289S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S185S | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | T321A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | T78T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | V192L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | F172V | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | F373L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S455Y | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | N85N | Silent | 1 |
| PRAD | Prostate adenocarcinoma | P250A | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P549S | Missense | 1 |
| READ | Rectum adenocarcinoma | E136* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | F369F | Silent | 1 |
| READ | Rectum adenocarcinoma | R82C | Missense | 1 |
| READ | Rectum adenocarcinoma | V312I | Missense | 1 |
| SARC | Sarcoma | G810G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E176K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E370K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E418K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E458K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E593E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E891K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G699E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G928R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I322N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K265K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K268R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L32I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L520L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P298S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P678L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R492R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R6Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R841R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S415F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T724T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Y512H | Missense | 1 |
| STAD | Stomach adenocarcinoma | A338A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A738S | Missense | 1 |
| STAD | Stomach adenocarcinoma | D113V | Missense | 1 |
| STAD | Stomach adenocarcinoma | G702G | Silent | 1 |
| STAD | Stomach adenocarcinoma | I279V | Missense | 1 |
| STAD | Stomach adenocarcinoma | K129N | Missense | 1 |
| STAD | Stomach adenocarcinoma | K286N | Missense | 1 |
| STAD | Stomach adenocarcinoma | K801K | Silent | 1 |
| STAD | Stomach adenocarcinoma | L130S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P244H | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q258* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R27* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R27Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | T371T | Silent | 1 |
| STAD | Stomach adenocarcinoma | T784T | Silent | 1 |
| THCA | Thyroid carcinoma | A215E | Missense | 1 |
| THCA | Thyroid carcinoma | E96Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A432V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D931N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E123D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E370K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E453A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E592* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E592Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E743* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E888* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F369F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G320V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I758I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K246Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K483T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K515E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K71N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | M346I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P509H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q7* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q935H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R922K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S572L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T784T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T940I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V192L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V439V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 2.7 | 8.4 | 16.7 |
| BRCA | Breast invasive carcinoma | 976 | 2.7 | 3.4 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.5 | 0 |
| COAD | Colon adenocarcinoma | 367 | 8.1 | 6.7 | 5.6 |
| ESCA | Esophageal carcinoma | 185 | 2.7 | 1.7 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.5 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 5.4 | 5 | 5.6 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 5.4 | 0.8 | 11.1 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 2.7 | 1.7 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 5.4 | 0.8 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 8.1 | 16.8 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 8.1 | 2.5 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.7 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0.8 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 2.7 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.7 | 0 |
| READ | Rectum adenocarcinoma | 122 | 2.7 | 1.7 | 5.6 |
| SARC | Sarcoma | 247 | 2.7 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 16.2 | 17.6 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 13.5 | 6.7 | 11.1 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.7 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 10.8 | 15.1 | 44.4 |