Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | R66C | Missense | 3 |
| LIHC | Liver hepatocellular carcinoma | E123K | Missense | 2 |
| STAD | Stomach adenocarcinoma | D216D | Silent | 2 |
| STAD | Stomach adenocarcinoma | R66C | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D344N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1041K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E259G | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E259Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E661K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G433D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G924R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I371I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | K906N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L614L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R182R | Silent | 1 |
| BRCA | Breast invasive carcinoma | E599A | Missense | 1 |
| BRCA | Breast invasive carcinoma | G1069G | Silent | 1 |
| BRCA | Breast invasive carcinoma | H596Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | M421V | Missense | 1 |
| BRCA | Breast invasive carcinoma | V25G | Missense | 1 |
| CESC | Cervical and endocervical cancers | E694K | Missense | 1 |
| CESC | Cervical and endocervical cancers | I669M | Missense | 1 |
| CESC | Cervical and endocervical cancers | L607F | Missense | 1 |
| CESC | Cervical and endocervical cancers | P53Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | W478C | Missense | 1 |
| COAD | Colon adenocarcinoma | A16V | Missense | 1 |
| COAD | Colon adenocarcinoma | A861V | Missense | 1 |
| COAD | Colon adenocarcinoma | G149D | Missense | 1 |
| COAD | Colon adenocarcinoma | H162H | Silent | 1 |
| COAD | Colon adenocarcinoma | P948T | Missense | 1 |
| COAD | Colon adenocarcinoma | R1185H | Missense | 1 |
| COAD | Colon adenocarcinoma | R1199H | Missense | 1 |
| COAD | Colon adenocarcinoma | R392W | Missense | 1 |
| COAD | Colon adenocarcinoma | R551Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R59C | Missense | 1 |
| COAD | Colon adenocarcinoma | R722C | Missense | 1 |
| COAD | Colon adenocarcinoma | T829T | Silent | 1 |
| ESCA | Esophageal carcinoma | C413C | Silent | 1 |
| ESCA | Esophageal carcinoma | R1110Q | Missense | 1 |
| ESCA | Esophageal carcinoma | R491L | Missense | 1 |
| ESCA | Esophageal carcinoma | R595R | Silent | 1 |
| ESCA | Esophageal carcinoma | R836R | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K8K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R439H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R611W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R638C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R805H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R996R | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | G804G | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | V1145L | Missense | 1 |
| LAML | Acute Myeloid Leukemia | V981A | Missense | 1 |
| LGG | Brain Lower Grade Glioma | C400C | Silent | 1 |
| LGG | Brain Lower Grade Glioma | D1212N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | D48N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P142T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V81V | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | E155E | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | F436L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G1117V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R106C | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S702C | Missense | 1 |
| LUAD | Lung adenocarcinoma | E828Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | G393G | Silent | 1 |
| LUAD | Lung adenocarcinoma | G875C | Missense | 1 |
| LUAD | Lung adenocarcinoma | H1116Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | M295V | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1028P | Silent | 1 |
| LUAD | Lung adenocarcinoma | P899P | Silent | 1 |
| LUAD | Lung adenocarcinoma | T365T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | G553G | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | H923H | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L1157L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L699L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | P1121H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q1189L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R1185C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Y443Y | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | G475R | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | H541Q | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L630L | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | R907R | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | I624N | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S926R | Missense | 1 |
| PRAD | Prostate adenocarcinoma | K64R | Missense | 1 |
| PRAD | Prostate adenocarcinoma | N1183S | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R106H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R97C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | Y215C | Missense | 1 |
| READ | Rectum adenocarcinoma | F409I | Missense | 1 |
| READ | Rectum adenocarcinoma | R733W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A732A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D221G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H165Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L790L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | N229I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P324P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P555S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P876S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P899P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P948L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P948P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1052S | Silent | 1 |
| STAD | Stomach adenocarcinoma | E272K | Missense | 1 |
| STAD | Stomach adenocarcinoma | G929G | Silent | 1 |
| STAD | Stomach adenocarcinoma | I244I | Silent | 1 |
| STAD | Stomach adenocarcinoma | K620N | Missense | 1 |
| STAD | Stomach adenocarcinoma | L1162L | Silent | 1 |
| STAD | Stomach adenocarcinoma | P311P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P457S | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q735R | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q918H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R109H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R29Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R69H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S1029F | Missense | 1 |
| STAD | Stomach adenocarcinoma | V107I | Missense | 1 |
| STAD | Stomach adenocarcinoma | W356* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | Y305Y | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | E578D | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | R602R | Silent | 1 |
| THYM | Thymoma | P904P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A299V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A486V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C397C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C413C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1132E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1058G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G264G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L614F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L893M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N1183S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N708N | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P378S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q55* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q623* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R231H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R232W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R29* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R491Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R559C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R734H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T1019T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y199C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 6.2 | 8.3 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 2.1 | 4.2 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 5.2 | 0 |
| COAD | Colon adenocarcinoma | 367 | 4.2 | 13.5 | 0 |
| ESCA | Esophageal carcinoma | 185 | 6.2 | 2.1 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 4.2 | 4.2 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 2.1 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 1 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 4.2 | 3.1 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 2.1 | 6.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 8.3 | 4.2 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 10.4 | 3.1 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 4.2 | 2.1 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.1 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 5.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.1 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 12.5 | 6.2 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 14.6 | 12.5 | 25 |
| TGCT | Testicular Germ Cell Tumors | 147 | 2.1 | 1 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 2.1 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 14.6 | 12.5 | 75 |