Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| LGG | Brain Lower Grade Glioma | V437G | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | P624S | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A278T | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | C259Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D1163N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1025K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1128K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E185Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I404I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | I700I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | K78K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L187L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L230F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R39R | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R502Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S19F | Missense | 1 |
| BRCA | Breast invasive carcinoma | A844A | Silent | 1 |
| BRCA | Breast invasive carcinoma | D174H | Missense | 1 |
| BRCA | Breast invasive carcinoma | D635N | Missense | 1 |
| BRCA | Breast invasive carcinoma | E590Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | F675V | Missense | 1 |
| BRCA | Breast invasive carcinoma | G986E | Missense | 1 |
| BRCA | Breast invasive carcinoma | K1164K | Silent | 1 |
| BRCA | Breast invasive carcinoma | L930L | Silent | 1 |
| BRCA | Breast invasive carcinoma | N902S | Missense | 1 |
| CESC | Cervical and endocervical cancers | H524N | Missense | 1 |
| CESC | Cervical and endocervical cancers | Q10Q | Silent | 1 |
| CESC | Cervical and endocervical cancers | R764C | Missense | 1 |
| CESC | Cervical and endocervical cancers | S124* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | C1014Y | Missense | 1 |
| COAD | Colon adenocarcinoma | D539G | Missense | 1 |
| COAD | Colon adenocarcinoma | G277G | Silent | 1 |
| COAD | Colon adenocarcinoma | I60I | Silent | 1 |
| COAD | Colon adenocarcinoma | K831R | Missense | 1 |
| COAD | Colon adenocarcinoma | P388S | Missense | 1 |
| COAD | Colon adenocarcinoma | P704L | Missense | 1 |
| COAD | Colon adenocarcinoma | P704P | Silent | 1 |
| COAD | Colon adenocarcinoma | R1035L | Missense | 1 |
| COAD | Colon adenocarcinoma | R570W | Missense | 1 |
| COAD | Colon adenocarcinoma | R875S | Missense | 1 |
| COAD | Colon adenocarcinoma | R897H | Missense | 1 |
| COAD | Colon adenocarcinoma | R925H | Missense | 1 |
| COAD | Colon adenocarcinoma | S984S | Silent | 1 |
| COAD | Colon adenocarcinoma | T1031M | Missense | 1 |
| COAD | Colon adenocarcinoma | W254* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | A1082T | Missense | 1 |
| ESCA | Esophageal carcinoma | E251K | Missense | 1 |
| ESCA | Esophageal carcinoma | K1132K | Silent | 1 |
| GBM | Glioblastoma multiforme | S1008S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A37T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E151K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E952K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I310V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P857S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1085P | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R570W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R572K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Y154C | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | A615T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | K1004K | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | M587T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R577R | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | V1179L | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | K873R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E712K | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R677* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q354P | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R570L | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1123* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E983K | Missense | 1 |
| LUAD | Lung adenocarcinoma | E987E | Silent | 1 |
| LUAD | Lung adenocarcinoma | F231F | Silent | 1 |
| LUAD | Lung adenocarcinoma | G285E | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q1146H | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q330H | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1071H | Missense | 1 |
| LUAD | Lung adenocarcinoma | R721C | Missense | 1 |
| LUAD | Lung adenocarcinoma | R973R | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | A135P | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A562V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q530* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | R694Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R973W | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V1080V | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | K98R | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R257H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | G1009R | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R514W | Missense | 1 |
| PRAD | Prostate adenocarcinoma | C243C | Silent | 1 |
| PRAD | Prostate adenocarcinoma | R897C | Missense | 1 |
| READ | Rectum adenocarcinoma | E73K | Missense | 1 |
| READ | Rectum adenocarcinoma | I966I | Silent | 1 |
| READ | Rectum adenocarcinoma | W254C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A688V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A777V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A961G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F1134F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F675F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H349Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L370L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1067L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1115L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P18S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P247S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P401S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q530* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R120C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R495K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1198S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S760S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S846F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S90S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V517V | Silent | 1 |
| STAD | Stomach adenocarcinoma | E1078V | Missense | 1 |
| STAD | Stomach adenocarcinoma | E411G | Missense | 1 |
| STAD | Stomach adenocarcinoma | E424K | Missense | 1 |
| STAD | Stomach adenocarcinoma | L605P | Missense | 1 |
| STAD | Stomach adenocarcinoma | L898F | Missense | 1 |
| STAD | Stomach adenocarcinoma | P132L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1171H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1129T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1186A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D56N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F722L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H113N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K414N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K449N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K91N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P266P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R39Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R561R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R5H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R926R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T542P | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 14.7 | 8.2 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 8.8 | 6.2 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 2.9 | 2.1 | 16.7 |
| COAD | Colon adenocarcinoma | 367 | 11.8 | 11.3 | 16.7 |
| ESCA | Esophageal carcinoma | 185 | 2.9 | 2.1 | 0 |
| GBM | Glioblastoma multiforme | 283 | 2.9 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 9.3 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 5.9 | 3.1 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 3.1 | 16.7 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 2.1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 8.8 | 6.2 | 16.7 |
| LUSC | Lung squamous cell carcinoma | 177 | 2.9 | 4.1 | 16.7 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.1 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.1 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 2.9 | 1 | 0 |
| READ | Rectum adenocarcinoma | 122 | 2.9 | 2.1 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 20.6 | 14.4 | 16.7 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 7.2 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 11.8 | 12.4 | 0 |