Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| UCEC | Uterine Corpus Endometrial Carcinoma | R887Q | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S2131S | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | D535H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D570N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D698H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1144K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1757K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E2294K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E552K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F1438L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G597V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I1382M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I413M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I771M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L1179I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L266L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P314L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P584H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q727H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R1483R | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R569K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R969* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S110C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S2293F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S330F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T1934M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V2237D | Missense | 1 |
| BRCA | Breast invasive carcinoma | A1184G | Missense | 1 |
| BRCA | Breast invasive carcinoma | D1764H | Missense | 1 |
| BRCA | Breast invasive carcinoma | D1831H | Missense | 1 |
| BRCA | Breast invasive carcinoma | D1906D | Silent | 1 |
| BRCA | Breast invasive carcinoma | E1146Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | E1714* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | E1986Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | E401D | Missense | 1 |
| BRCA | Breast invasive carcinoma | F1812L | Missense | 1 |
| BRCA | Breast invasive carcinoma | G1864E | Missense | 1 |
| BRCA | Breast invasive carcinoma | I81I | Silent | 1 |
| BRCA | Breast invasive carcinoma | L1700L | Silent | 1 |
| BRCA | Breast invasive carcinoma | R1595T | Missense | 1 |
| BRCA | Breast invasive carcinoma | R808I | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1223C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1650C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1798T | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1822A | Missense | 1 |
| BRCA | Breast invasive carcinoma | S205L | Missense | 1 |
| BRCA | Breast invasive carcinoma | W1082S | Missense | 1 |
| CESC | Cervical and endocervical cancers | D469N | Missense | 1 |
| CESC | Cervical and endocervical cancers | D646H | Missense | 1 |
| CESC | Cervical and endocervical cancers | E1828K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E2064K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E820K | Missense | 1 |
| CESC | Cervical and endocervical cancers | R154P | Missense | 1 |
| CESC | Cervical and endocervical cancers | R881T | Missense | 1 |
| CESC | Cervical and endocervical cancers | S1786N | Missense | 1 |
| CESC | Cervical and endocervical cancers | S791L | Missense | 1 |
| COAD | Colon adenocarcinoma | E1003* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | E992E | Silent | 1 |
| COAD | Colon adenocarcinoma | I1353V | Missense | 1 |
| COAD | Colon adenocarcinoma | I201I | Silent | 1 |
| COAD | Colon adenocarcinoma | L1618I | Missense | 1 |
| COAD | Colon adenocarcinoma | N875T | Missense | 1 |
| COAD | Colon adenocarcinoma | Q579K | Missense | 1 |
| COAD | Colon adenocarcinoma | R1056C | Missense | 1 |
| COAD | Colon adenocarcinoma | R1433* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R2270Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R887* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | S102Y | Missense | 1 |
| COAD | Colon adenocarcinoma | S1249S | Silent | 1 |
| COAD | Colon adenocarcinoma | S1555F | Missense | 1 |
| COAD | Colon adenocarcinoma | S855S | Silent | 1 |
| COAD | Colon adenocarcinoma | V1326M | Missense | 1 |
| COAD | Colon adenocarcinoma | W395C | Missense | 1 |
| COAD | Colon adenocarcinoma | W395L | Missense | 1 |
| COAD | Colon adenocarcinoma | Y1313H | Missense | 1 |
| ESCA | Esophageal carcinoma | E1243* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | L1149F | Missense | 1 |
| ESCA | Esophageal carcinoma | R1626Q | Missense | 1 |
| ESCA | Esophageal carcinoma | S1898F | Missense | 1 |
| ESCA | Esophageal carcinoma | S822L | Missense | 1 |
| ESCA | Esophageal carcinoma | T1748K | Missense | 1 |
| GBM | Glioblastoma multiforme | S1611* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1559K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E844K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E992V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G324G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N2318N | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P688S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P724A | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q1426R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q174L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R2270* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1506* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1720* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E2125D | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G624A | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | I361L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | M1358V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P1775T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R2100R | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | S1548S | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | V2193F | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Y1197H | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | I483F | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L79W | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S214* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | A1186T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | D848G | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E1241K | Missense | 1 |
| LGG | Brain Lower Grade Glioma | G1565R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | I1845V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R648C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R84H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R926G | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S102Y | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S1435R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T1816N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T2103T | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | E1681E | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | G1158G | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | I1876M | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K2106R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L2309F | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N704S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N875S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R2031R | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | R813S | Missense | 1 |
| LUAD | Lung adenocarcinoma | D1824E | Missense | 1 |
| LUAD | Lung adenocarcinoma | H2208L | Missense | 1 |
| LUAD | Lung adenocarcinoma | L1976F | Missense | 1 |
| LUAD | Lung adenocarcinoma | L655P | Missense | 1 |
| LUAD | Lung adenocarcinoma | L880V | Missense | 1 |
| LUAD | Lung adenocarcinoma | M997V | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q1698* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | S1898S | Silent | 1 |
| LUAD | Lung adenocarcinoma | S1904C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S2253* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | D1872H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E2004K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G1565V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L89F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P1853T | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q1340K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S2273C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | W2315L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R108S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S145F | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | W395C | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A1369A | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | E685E | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | G324G | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | N1610Y | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | N983T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R1441L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R1441R | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R1441W | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R2270Q | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S404N | Missense | 1 |
| PRAD | Prostate adenocarcinoma | E138K | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G2098D | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P1118S | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S1289I | Missense | 1 |
| READ | Rectum adenocarcinoma | A1224A | Silent | 1 |
| READ | Rectum adenocarcinoma | E835D | Missense | 1 |
| READ | Rectum adenocarcinoma | S2273Y | Missense | 1 |
| READ | Rectum adenocarcinoma | T1816N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D1036N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G1187S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G1503G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G1592R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H346Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I405F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1094Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1211* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1397R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R1558C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S110F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1497F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S2047F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S228F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S285C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S307F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S419F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S419S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S696R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V1215L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V1646A | Missense | 1 |
| STAD | Stomach adenocarcinoma | A1224V | Missense | 1 |
| STAD | Stomach adenocarcinoma | C1593C | Silent | 1 |
| STAD | Stomach adenocarcinoma | D1821V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D2288N | Missense | 1 |
| STAD | Stomach adenocarcinoma | G873D | Missense | 1 |
| STAD | Stomach adenocarcinoma | K1416E | Missense | 1 |
| STAD | Stomach adenocarcinoma | L18M | Missense | 1 |
| STAD | Stomach adenocarcinoma | P584A | Missense | 1 |
| STAD | Stomach adenocarcinoma | R108R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R1441Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1441W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R708C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R725H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R886* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | S840L | Missense | 1 |
| STAD | Stomach adenocarcinoma | S96T | Missense | 1 |
| STAD | Stomach adenocarcinoma | T2181M | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | K1319R | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | L1384M | Missense | 1 |
| THCA | Thyroid carcinoma | H120R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1708V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A2238T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A872A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D1947Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D2287A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D673Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E2250* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E842D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E940* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G873G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H506Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I1927M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | M1842I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | M1842K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N2025S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N2034D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N2084N | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P1195P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P2108H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P280L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1211* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1433* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1626Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1930I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R2094H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R2270Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R313H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R709H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R969* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T1971I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T2181M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V1587I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V2226V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | W1157R | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 5.7 | 11.7 | 5 |
| BRCA | Breast invasive carcinoma | 976 | 8.6 | 8.5 | 5 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 4.8 | 0 |
| COAD | Colon adenocarcinoma | 367 | 11.4 | 6.4 | 15 |
| ESCA | Esophageal carcinoma | 185 | 0 | 2.7 | 5 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 5 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 5.7 | 3.7 | 15 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 5.7 | 3.7 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.1 | 5 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 2.9 | 5.9 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 8.6 | 3.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 2.9 | 3.7 | 10 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.6 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 11.4 | 3.2 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.1 | 0 |
| READ | Rectum adenocarcinoma | 122 | 2.9 | 1.6 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 8.6 | 9 | 5 |
| STAD | Stomach adenocarcinoma | 393 | 5.7 | 7.4 | 5 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.1 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0.5 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 20 | 13.8 | 25 |