Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | A55V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q382* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | G329E | Missense | 1 |
| BRCA | Breast invasive carcinoma | L49P | Missense | 1 |
| BRCA | Breast invasive carcinoma | S315N | Missense | 1 |
| BRCA | Breast invasive carcinoma | T305P | Missense | 1 |
| BRCA | Breast invasive carcinoma | V361L | Missense | 1 |
| COAD | Colon adenocarcinoma | E359E | Silent | 1 |
| COAD | Colon adenocarcinoma | G317R | Missense | 1 |
| COAD | Colon adenocarcinoma | G317V | Missense | 1 |
| COAD | Colon adenocarcinoma | G318E | Missense | 1 |
| COAD | Colon adenocarcinoma | G73V | Missense | 1 |
| COAD | Colon adenocarcinoma | R20R | Silent | 1 |
| COAD | Colon adenocarcinoma | R72C | Missense | 1 |
| COAD | Colon adenocarcinoma | R72H | Missense | 1 |
| COAD | Colon adenocarcinoma | S219S | Silent | 1 |
| ESCA | Esophageal carcinoma | L231P | Missense | 1 |
| ESCA | Esophageal carcinoma | L29L | Silent | 1 |
| ESCA | Esophageal carcinoma | P201L | Missense | 1 |
| GBM | Glioblastoma multiforme | S110L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G193G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G312G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R62T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S316C | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L231V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T372T | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | K88R | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q327R | Missense | 1 |
| LUAD | Lung adenocarcinoma | T364T | Silent | 1 |
| LUAD | Lung adenocarcinoma | V284L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L300P | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R322G | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | E347G | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R288K | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S256S | Silent | 1 |
| SARC | Sarcoma | R172W | Missense | 1 |
| SARC | Sarcoma | R25H | Missense | 1 |
| SARC | Sarcoma | S140N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D209N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I48I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L124F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P192S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P203P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R204W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T372T | Silent | 1 |
| STAD | Stomach adenocarcinoma | A99P | Missense | 1 |
| STAD | Stomach adenocarcinoma | E58Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R72C | Missense | 1 |
| STAD | Stomach adenocarcinoma | S36P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D232D | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D301Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G221S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K70R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R174C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S40I | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 2.4 | 100 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 12.2 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 23.1 | 14.6 | 0 |
| ESCA | Esophageal carcinoma | 185 | 7.7 | 4.9 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.4 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 15.4 | 4.9 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.4 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 7.7 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 2.4 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 7.7 | 4.9 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.9 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 7.7 | 2.4 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 7.3 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 23.1 | 9.8 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 9.8 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 7.7 | 12.2 | 0 |