Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | F430F | Silent | 3 |
| BLCA | Bladder urothelial carcinoma | D386N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E215K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q592H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S455C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V445V | Silent | 1 |
| BRCA | Breast invasive carcinoma | D229G | Missense | 1 |
| BRCA | Breast invasive carcinoma | D483N | Missense | 1 |
| BRCA | Breast invasive carcinoma | G484G | Silent | 1 |
| BRCA | Breast invasive carcinoma | I456V | Missense | 1 |
| BRCA | Breast invasive carcinoma | R410* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | S362L | Missense | 1 |
| BRCA | Breast invasive carcinoma | T473T | Silent | 1 |
| COAD | Colon adenocarcinoma | D317D | Silent | 1 |
| COAD | Colon adenocarcinoma | K73K | Silent | 1 |
| COAD | Colon adenocarcinoma | R329H | Missense | 1 |
| COAD | Colon adenocarcinoma | S387R | Missense | 1 |
| COAD | Colon adenocarcinoma | S393S | Silent | 1 |
| COAD | Colon adenocarcinoma | S542L | Missense | 1 |
| COAD | Colon adenocarcinoma | Y105H | Missense | 1 |
| ESCA | Esophageal carcinoma | *599* | Silent | 1 |
| ESCA | Esophageal carcinoma | F478F | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E363E | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I66I | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N132I | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G269D | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S287P | Missense | 1 |
| LGG | Brain Lower Grade Glioma | C401Y | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R184Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K175R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N186K | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q227K | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R340T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V398V | Silent | 1 |
| LUAD | Lung adenocarcinoma | E160* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E218* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E218D | Missense | 1 |
| LUAD | Lung adenocarcinoma | E363* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | G226C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G255W | Missense | 1 |
| LUAD | Lung adenocarcinoma | G484C | Missense | 1 |
| LUAD | Lung adenocarcinoma | H354R | Missense | 1 |
| LUAD | Lung adenocarcinoma | P268L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R124K | Missense | 1 |
| LUAD | Lung adenocarcinoma | R313S | Missense | 1 |
| LUAD | Lung adenocarcinoma | V198L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | C515F | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L181L | Silent | 1 |
| PRAD | Prostate adenocarcinoma | S287P | Missense | 1 |
| PRAD | Prostate adenocarcinoma | T381M | Missense | 1 |
| READ | Rectum adenocarcinoma | A465S | Missense | 1 |
| READ | Rectum adenocarcinoma | D317D | Silent | 1 |
| READ | Rectum adenocarcinoma | F430F | Silent | 1 |
| READ | Rectum adenocarcinoma | V390L | Missense | 1 |
| SARC | Sarcoma | T303A | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F430F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H107Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L379P | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S580L | Missense | 1 |
| STAD | Stomach adenocarcinoma | A511V | Missense | 1 |
| STAD | Stomach adenocarcinoma | F434S | Missense | 1 |
| STAD | Stomach adenocarcinoma | G283R | Missense | 1 |
| STAD | Stomach adenocarcinoma | G297W | Missense | 1 |
| STAD | Stomach adenocarcinoma | G527R | Missense | 1 |
| STAD | Stomach adenocarcinoma | I595I | Silent | 1 |
| STAD | Stomach adenocarcinoma | P222P | Silent | 1 |
| STAD | Stomach adenocarcinoma | Q522Q | Silent | 1 |
| STAD | Stomach adenocarcinoma | R112H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R410* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R556C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R82W | Missense | 1 |
| STAD | Stomach adenocarcinoma | S214S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S420I | Missense | 1 |
| STAD | Stomach adenocarcinoma | T353A | Missense | 1 |
| STAD | Stomach adenocarcinoma | V154M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V209L | Missense | 1 |
| STAD | Stomach adenocarcinoma | V308V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C460C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D325G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E160K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G242R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N500N | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R82Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S304S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S397S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V223I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V398I | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 3.7 | 7 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 7.4 | 7 | 20 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 22.2 | 7 | 0 |
| ESCA | Esophageal carcinoma | 185 | 7.4 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 7.4 | 1.8 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 3.5 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 3.5 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.7 | 7 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 15.8 | 60 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 1.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 3.7 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 3.5 | 0 |
| READ | Rectum adenocarcinoma | 122 | 7.4 | 3.5 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.8 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 3.7 | 5.3 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 18.5 | 21.1 | 20 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 14.8 | 10.5 | 0 |