Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | R248Q | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | P112P | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | D160D | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | E167E | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | F260L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K19K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | V350M | Missense | 1 |
| BRCA | Breast invasive carcinoma | C247G | Missense | 1 |
| BRCA | Breast invasive carcinoma | F260L | Missense | 1 |
| BRCA | Breast invasive carcinoma | I370I | Silent | 1 |
| BRCA | Breast invasive carcinoma | L365L | Silent | 1 |
| COAD | Colon adenocarcinoma | A208D | Missense | 1 |
| COAD | Colon adenocarcinoma | A377T | Missense | 1 |
| COAD | Colon adenocarcinoma | C393S | Missense | 1 |
| COAD | Colon adenocarcinoma | D293D | Silent | 1 |
| COAD | Colon adenocarcinoma | D473D | Silent | 1 |
| COAD | Colon adenocarcinoma | E202G | Missense | 1 |
| COAD | Colon adenocarcinoma | R108Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R330Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R387C | Missense | 1 |
| COAD | Colon adenocarcinoma | T261M | Missense | 1 |
| COAD | Colon adenocarcinoma | T38T | Silent | 1 |
| COAD | Colon adenocarcinoma | Y137C | Missense | 1 |
| ESCA | Esophageal carcinoma | G57R | Missense | 1 |
| ESCA | Esophageal carcinoma | V404V | Silent | 1 |
| GBM | Glioblastoma multiforme | A161A | Silent | 1 |
| GBM | Glioblastoma multiforme | K150R | Missense | 1 |
| GBM | Glioblastoma multiforme | T134M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A226V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A290T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D194D | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D501N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L495P | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P348R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P399L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | I349I | Silent | 1 |
| LGG | Brain Lower Grade Glioma | N154N | Silent | 1 |
| LGG | Brain Lower Grade Glioma | P116T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R387C | Missense | 1 |
| LUAD | Lung adenocarcinoma | L45F | Missense | 1 |
| LUAD | Lung adenocarcinoma | P356Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | R82P | Missense | 1 |
| LUAD | Lung adenocarcinoma | S68* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | V474V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | G33R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | K76T | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L480P | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S266C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L298L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | D129G | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R106W | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R82* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | Y230Y | Silent | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | A226A | Silent | 1 |
| READ | Rectum adenocarcinoma | A286A | Silent | 1 |
| READ | Rectum adenocarcinoma | K19N | Missense | 1 |
| READ | Rectum adenocarcinoma | L482F | Missense | 1 |
| SARC | Sarcoma | E10G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E327K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G361G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I279I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I343I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I401I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K228K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K98R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L471L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P219L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P382L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P96L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P96S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q153Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R108Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R250Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S489F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V231L | Missense | 1 |
| STAD | Stomach adenocarcinoma | A201A | Silent | 1 |
| STAD | Stomach adenocarcinoma | C247C | Silent | 1 |
| STAD | Stomach adenocarcinoma | E202D | Missense | 1 |
| STAD | Stomach adenocarcinoma | G162S | Missense | 1 |
| STAD | Stomach adenocarcinoma | K133N | Missense | 1 |
| STAD | Stomach adenocarcinoma | L298L | Silent | 1 |
| STAD | Stomach adenocarcinoma | N289N | Silent | 1 |
| STAD | Stomach adenocarcinoma | R248W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R464W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R82Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R92R | Silent | 1 |
| STAD | Stomach adenocarcinoma | S301S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S34N | Missense | 1 |
| STAD | Stomach adenocarcinoma | S429S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T261M | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y32Y | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | G191D | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | L492I | Missense | 1 |
| THCA | Thyroid carcinoma | L181L | Silent | 1 |
| THCA | Thyroid carcinoma | L485L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D14E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V351A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V404V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 7.9 | 3.3 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 5.3 | 3.3 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 7.9 | 18.3 | 0 |
| ESCA | Esophageal carcinoma | 185 | 2.6 | 1.7 | 0 |
| GBM | Glioblastoma multiforme | 283 | 2.6 | 3.3 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 2.6 | 10 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 5.3 | 3.3 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 2.6 | 5 | 50 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 6.7 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2.6 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 2.6 | 3.3 | 50 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 2.6 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 2.6 | 3.3 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.7 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 23.7 | 16.7 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 21.1 | 13.3 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 3.3 | 0 |
| THCA | Thyroid carcinoma | 495 | 5.3 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 2.6 | 3.3 | 0 |