Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | D1680D | Silent | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1189Q | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D1099Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D228G | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1170* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E71D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H1536Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L206I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L626V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L694L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P1232A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q317* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q485* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q938E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R1054* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R1153* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R1167Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1025* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S30C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y1270C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y522C | Missense | 1 |
| BRCA | Breast invasive carcinoma | E379K | Missense | 1 |
| BRCA | Breast invasive carcinoma | K311R | Missense | 1 |
| BRCA | Breast invasive carcinoma | K620N | Missense | 1 |
| BRCA | Breast invasive carcinoma | R230R | Silent | 1 |
| BRCA | Breast invasive carcinoma | R732S | Missense | 1 |
| BRCA | Breast invasive carcinoma | R900Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | S36C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S624C | Missense | 1 |
| BRCA | Breast invasive carcinoma | V139V | Silent | 1 |
| CESC | Cervical and endocervical cancers | E1398K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E652Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | F1082F | Silent | 1 |
| CESC | Cervical and endocervical cancers | G951C | Missense | 1 |
| CESC | Cervical and endocervical cancers | H1628Y | Missense | 1 |
| CESC | Cervical and endocervical cancers | L206L | Silent | 1 |
| COAD | Colon adenocarcinoma | D1680G | Missense | 1 |
| COAD | Colon adenocarcinoma | E1105K | Missense | 1 |
| COAD | Colon adenocarcinoma | G289G | Silent | 1 |
| COAD | Colon adenocarcinoma | K1139T | Missense | 1 |
| COAD | Colon adenocarcinoma | K1429Q | Missense | 1 |
| COAD | Colon adenocarcinoma | K204E | Missense | 1 |
| COAD | Colon adenocarcinoma | K204R | Missense | 1 |
| COAD | Colon adenocarcinoma | P368S | Missense | 1 |
| COAD | Colon adenocarcinoma | R1091K | Missense | 1 |
| COAD | Colon adenocarcinoma | R1112H | Missense | 1 |
| COAD | Colon adenocarcinoma | R1120W | Missense | 1 |
| COAD | Colon adenocarcinoma | R1189Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R1420I | Missense | 1 |
| COAD | Colon adenocarcinoma | R1574I | Missense | 1 |
| COAD | Colon adenocarcinoma | R1611M | Missense | 1 |
| COAD | Colon adenocarcinoma | R233H | Missense | 1 |
| COAD | Colon adenocarcinoma | S90N | Missense | 1 |
| COAD | Colon adenocarcinoma | T577T | Silent | 1 |
| COAD | Colon adenocarcinoma | V814A | Missense | 1 |
| ESCA | Esophageal carcinoma | E1405K | Missense | 1 |
| ESCA | Esophageal carcinoma | G1143D | Missense | 1 |
| ESCA | Esophageal carcinoma | H1549N | Missense | 1 |
| ESCA | Esophageal carcinoma | H1557Y | Missense | 1 |
| ESCA | Esophageal carcinoma | M813V | Missense | 1 |
| ESCA | Esophageal carcinoma | P450P | Silent | 1 |
| ESCA | Esophageal carcinoma | R827H | Missense | 1 |
| ESCA | Esophageal carcinoma | V913I | Missense | 1 |
| ESCA | Esophageal carcinoma | Y530C | Missense | 1 |
| GBM | Glioblastoma multiforme | H1628Y | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G867G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K1567N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q317E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1153Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1363P | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S158C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S446* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | A926T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S1385A | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | E168G | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | H1640Y | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | M346K | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Y1497C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | D1159D | Silent | 1 |
| LGG | Brain Lower Grade Glioma | E526V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | I1251T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R1560Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A609S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G15G | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | K431T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N1122D | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R1601* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | A779A | Silent | 1 |
| LUAD | Lung adenocarcinoma | E65K | Missense | 1 |
| LUAD | Lung adenocarcinoma | F748L | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1143C | Missense | 1 |
| LUAD | Lung adenocarcinoma | K1374N | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q194E | Missense | 1 |
| LUAD | Lung adenocarcinoma | R281R | Silent | 1 |
| LUAD | Lung adenocarcinoma | T1650T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | G405V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | H687N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q1552K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q546P | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | W332S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | E778D | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | K204N | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L1180L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | M1275I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | D1614D | Silent | 1 |
| PRAD | Prostate adenocarcinoma | G612R | Missense | 1 |
| PRAD | Prostate adenocarcinoma | Q1051* | Nonsense | 1 |
| PRAD | Prostate adenocarcinoma | Q1681Q | Silent | 1 |
| PRAD | Prostate adenocarcinoma | R1504W | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R1626T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R900Q | Missense | 1 |
| PRAD | Prostate adenocarcinoma | V1011V | Silent | 1 |
| PRAD | Prostate adenocarcinoma | W1664* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | E984K | Missense | 1 |
| READ | Rectum adenocarcinoma | R230I | Missense | 1 |
| SARC | Sarcoma | N239I | Missense | 1 |
| SARC | Sarcoma | V188F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D632N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K582N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L1438F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L640F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | M346I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1232L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1116R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R1708Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R583W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R696R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R827C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1545F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S164* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | T1304T | Silent | 1 |
| STAD | Stomach adenocarcinoma | A852A | Silent | 1 |
| STAD | Stomach adenocarcinoma | C1242C | Silent | 1 |
| STAD | Stomach adenocarcinoma | E1188G | Missense | 1 |
| STAD | Stomach adenocarcinoma | K1362Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | L1317L | Silent | 1 |
| STAD | Stomach adenocarcinoma | L510I | Missense | 1 |
| STAD | Stomach adenocarcinoma | L534* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | L792I | Missense | 1 |
| STAD | Stomach adenocarcinoma | N1514D | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1189Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R233C | Missense | 1 |
| STAD | Stomach adenocarcinoma | S1580S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S20L | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | K401M | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | Q107Q | Silent | 1 |
| THCA | Thyroid carcinoma | H494Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1670A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C497Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D1367G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1063E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1220* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1419* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1464* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E244E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G870V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H1392Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H329R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K1382N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K145T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N1039K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1574I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1616M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 3.2 | 10.1 | 40 |
| BRCA | Breast invasive carcinoma | 976 | 6.5 | 5.9 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 6.5 | 3.4 | 0 |
| COAD | Colon adenocarcinoma | 367 | 12.9 | 14.3 | 0 |
| ESCA | Esophageal carcinoma | 185 | 3.2 | 6.7 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0.8 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.2 | 4.2 | 6.7 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.7 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 3.4 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 3.2 | 2.5 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.2 | 2.5 | 6.7 |
| LUAD | Lung adenocarcinoma | 533 | 9.7 | 4.2 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.2 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.7 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 3.2 | 0.8 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 9.7 | 3.4 | 13.3 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.7 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.7 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 9.7 | 8.4 | 6.7 |
| STAD | Stomach adenocarcinoma | 393 | 12.9 | 6.7 | 6.7 |
| TGCT | Testicular Germ Cell Tumors | 147 | 3.2 | 0.8 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0.8 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.7 | 10.1 | 20 |