Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | D15H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E176* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E183K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E234Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E27K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E397Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I131T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L417L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S364* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | G120V | Missense | 1 |
| COAD | Colon adenocarcinoma | E206E | Silent | 1 |
| COAD | Colon adenocarcinoma | F785L | Missense | 1 |
| COAD | Colon adenocarcinoma | R82* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | S487F | Missense | 1 |
| COAD | Colon adenocarcinoma | S59P | Missense | 1 |
| COAD | Colon adenocarcinoma | T754M | Missense | 1 |
| GBM | Glioblastoma multiforme | T139N | Missense | 1 |
| GBM | Glioblastoma multiforme | T4T | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E538Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G521V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K439K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q824* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q824L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R476T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R477G | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S823S | Silent | 1 |
| LGG | Brain Lower Grade Glioma | Q825Q | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | D69V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T656T | Silent | 1 |
| LUAD | Lung adenocarcinoma | A89S | Missense | 1 |
| LUAD | Lung adenocarcinoma | L118V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q652E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q828K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S431A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S570* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | S632L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | Q569L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L520* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | T711A | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | V52G | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A124T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P781P | Silent | 1 |
| READ | Rectum adenocarcinoma | D119N | Missense | 1 |
| READ | Rectum adenocarcinoma | K712E | Missense | 1 |
| READ | Rectum adenocarcinoma | S221Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A776T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E116* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | E206K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P159S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q775Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T687T | Silent | 1 |
| STAD | Stomach adenocarcinoma | A34V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D18A | Missense | 1 |
| STAD | Stomach adenocarcinoma | G63D | Missense | 1 |
| STAD | Stomach adenocarcinoma | H442H | Silent | 1 |
| STAD | Stomach adenocarcinoma | L342L | Silent | 1 |
| STAD | Stomach adenocarcinoma | L530V | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q190R | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q780H | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | V376A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F104L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F22F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G673R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L287M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q688R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R387* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S12L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S19G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T172A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T240A | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 7.7 | 12.2 | 25 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 2 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 7.7 | 8.2 | 12.5 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 7.7 | 2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 7.7 | 10.2 | 12.5 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 7.7 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 7.7 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 7.7 | 2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 4.1 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 8.2 | 12.5 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 4.1 | 12.5 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 7.7 | 2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 6.1 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 15.4 | 6.1 | 12.5 |
| STAD | Stomach adenocarcinoma | 393 | 15.4 | 12.2 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 2 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 7.7 | 16.3 | 12.5 |