Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | E423K | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D281H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D393H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E614K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E96K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R109H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S124L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V266V | Silent | 1 |
| BRCA | Breast invasive carcinoma | E362E | Silent | 1 |
| BRCA | Breast invasive carcinoma | M307I | Missense | 1 |
| CESC | Cervical and endocervical cancers | D571H | Missense | 1 |
| CESC | Cervical and endocervical cancers | E105K | Missense | 1 |
| COAD | Colon adenocarcinoma | A262V | Missense | 1 |
| COAD | Colon adenocarcinoma | R500C | Missense | 1 |
| COAD | Colon adenocarcinoma | R589H | Missense | 1 |
| COAD | Colon adenocarcinoma | R629R | Silent | 1 |
| COAD | Colon adenocarcinoma | T227T | Silent | 1 |
| ESCA | Esophageal carcinoma | T521K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A370V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E312K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E470K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G14G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K110K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K191K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M190I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M307I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R74T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S392L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V330V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | A654A | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | H51H | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | K428M | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R120H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R500C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R581C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R597W | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R581C | Missense | 1 |
| LUAD | Lung adenocarcinoma | A25V | Missense | 1 |
| LUAD | Lung adenocarcinoma | D393H | Missense | 1 |
| LUAD | Lung adenocarcinoma | G377R | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q438H | Missense | 1 |
| LUAD | Lung adenocarcinoma | R449S | Missense | 1 |
| LUAD | Lung adenocarcinoma | R623C | Missense | 1 |
| LUAD | Lung adenocarcinoma | T640T | Silent | 1 |
| LUAD | Lung adenocarcinoma | V266V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | D7H | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | C486F | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | F219L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | D301V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L637L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R522H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R83H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | T647A | Missense | 1 |
| READ | Rectum adenocarcinoma | R441H | Missense | 1 |
| SARC | Sarcoma | I484N | Missense | 1 |
| SARC | Sarcoma | P235L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F219F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G297E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H360H | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K191* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | K543E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P361S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R656C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R83C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S138L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Y28H | Missense | 1 |
| STAD | Stomach adenocarcinoma | A262A | Silent | 1 |
| STAD | Stomach adenocarcinoma | E268G | Missense | 1 |
| STAD | Stomach adenocarcinoma | E431K | Missense | 1 |
| STAD | Stomach adenocarcinoma | G108R | Missense | 1 |
| STAD | Stomach adenocarcinoma | G125W | Missense | 1 |
| STAD | Stomach adenocarcinoma | G14R | Missense | 1 |
| STAD | Stomach adenocarcinoma | G426S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R188Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R363M | Missense | 1 |
| STAD | Stomach adenocarcinoma | R589H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R620L | Missense | 1 |
| STAD | Stomach adenocarcinoma | T647A | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | A366A | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | T442T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C375C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G516V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H154Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H643H | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | M626T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R449R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R56Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R581H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R585H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R629R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T576M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 4.5 | 11.6 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 4.5 | 1.4 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.9 | 0 |
| COAD | Colon adenocarcinoma | 367 | 9.1 | 4.3 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 1.4 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 18.2 | 10.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 9.1 | 1.4 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 5.8 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 1.4 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 9.1 | 8.7 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 1.4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.9 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 4.5 | 2.9 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.9 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.4 | 0 |
| SARC | Sarcoma | 247 | 0 | 2.9 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 9.1 | 10.1 | 100 |
| STAD | Stomach adenocarcinoma | 393 | 4.5 | 15.9 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 9.1 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 18.2 | 10.1 | 0 |