Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| STAD | Stomach adenocarcinoma | R286H | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E243K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E285K | Missense | 1 |
| CESC | Cervical and endocervical cancers | Q269H | Missense | 1 |
| COAD | Colon adenocarcinoma | A274A | Silent | 1 |
| COAD | Colon adenocarcinoma | P302A | Missense | 1 |
| COAD | Colon adenocarcinoma | R368Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R400Q | Missense | 1 |
| COAD | Colon adenocarcinoma | T24S | Missense | 1 |
| ESCA | Esophageal carcinoma | R283R | Silent | 1 |
| ESCA | Esophageal carcinoma | R93W | Missense | 1 |
| GBM | Glioblastoma multiforme | R224* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M53I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P354P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V320V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | P313T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R224R | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A118T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L147L | Silent | 1 |
| LUAD | Lung adenocarcinoma | D267N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G413G | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | I436S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A220A | Silent | 1 |
| PRAD | Prostate adenocarcinoma | F111C | Missense | 1 |
| READ | Rectum adenocarcinoma | R170H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F126V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A308T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A411T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A422V | Missense | 1 |
| STAD | Stomach adenocarcinoma | E51D | Missense | 1 |
| STAD | Stomach adenocarcinoma | G52D | Missense | 1 |
| STAD | Stomach adenocarcinoma | R93W | Missense | 1 |
| STAD | Stomach adenocarcinoma | S139S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S369S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T284M | Missense | 1 |
| STAD | Stomach adenocarcinoma | T357M | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | A308S | Missense | 1 |
| THYM | Thymoma | R394H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D149N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E223K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G319A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G441G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L346V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N204N | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R236Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R392Q | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 2.9 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 2.9 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.9 | 0 |
| COAD | Colon adenocarcinoma | 367 | 8.3 | 11.8 | 0 |
| ESCA | Esophageal carcinoma | 185 | 8.3 | 2.9 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 100 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 16.7 | 2.9 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 8.3 | 2.9 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.9 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 8.3 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 2.9 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 8.3 | 2.9 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 8.3 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.9 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.9 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 0 | 2.9 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 16.7 | 29.4 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 2.9 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 2.9 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 16.7 | 17.6 | 0 |