Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| LAML | Acute Myeloid Leukemia | R882H | Missense | 19 |
| LAML | Acute Myeloid Leukemia | R882C | Missense | 7 |
| COAD | Colon adenocarcinoma | F414L | Missense | 2 |
| LAML | Acute Myeloid Leukemia | R736H | Missense | 2 |
| STAD | Stomach adenocarcinoma | D25D | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | A760T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | A884A | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | E863K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F827F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | G543V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G890D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H821R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K299I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L901L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | M880I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P405P | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R309P | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R53R | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | T834N | Missense | 1 |
| BRCA | Breast invasive carcinoma | E342K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E428Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | G890D | Missense | 1 |
| BRCA | Breast invasive carcinoma | K217T | Missense | 1 |
| BRCA | Breast invasive carcinoma | L605L | Silent | 1 |
| BRCA | Breast invasive carcinoma | R46R | Silent | 1 |
| BRCA | Breast invasive carcinoma | S393S | Silent | 1 |
| BRCA | Breast invasive carcinoma | V265M | Missense | 1 |
| BRCA | Breast invasive carcinoma | V48G | Missense | 1 |
| BRCA | Breast invasive carcinoma | W314G | Missense | 1 |
| CESC | Cervical and endocervical cancers | D394N | Missense | 1 |
| CESC | Cervical and endocervical cancers | R143Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | V467V | Silent | 1 |
| COAD | Colon adenocarcinoma | A192V | Missense | 1 |
| COAD | Colon adenocarcinoma | A462V | Missense | 1 |
| COAD | Colon adenocarcinoma | A910S | Missense | 1 |
| COAD | Colon adenocarcinoma | A910V | Missense | 1 |
| COAD | Colon adenocarcinoma | D92N | Missense | 1 |
| COAD | Colon adenocarcinoma | E281K | Missense | 1 |
| COAD | Colon adenocarcinoma | E482K | Missense | 1 |
| COAD | Colon adenocarcinoma | G234R | Missense | 1 |
| COAD | Colon adenocarcinoma | L188I | Missense | 1 |
| COAD | Colon adenocarcinoma | L905L | Silent | 1 |
| COAD | Colon adenocarcinoma | P5P | Silent | 1 |
| COAD | Colon adenocarcinoma | R46Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R478Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R635W | Missense | 1 |
| COAD | Colon adenocarcinoma | R720C | Missense | 1 |
| COAD | Colon adenocarcinoma | R882R | Silent | 1 |
| COAD | Colon adenocarcinoma | S304S | Silent | 1 |
| COAD | Colon adenocarcinoma | S393S | Silent | 1 |
| COAD | Colon adenocarcinoma | S714P | Missense | 1 |
| COAD | Colon adenocarcinoma | S770P | Missense | 1 |
| ESCA | Esophageal carcinoma | E177Q | Missense | 1 |
| ESCA | Esophageal carcinoma | G63S | Missense | 1 |
| ESCA | Esophageal carcinoma | H789H | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | C387C | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E371* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E907K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I493I | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K361K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K906K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L547L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L605L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P106S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P264P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P419L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P743P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R488Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R729Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R899C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S689C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | W893R | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | F290I | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | M585L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R326H | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R720P | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | T835M | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | W409* | Nonsense | 1 |
| LAML | Acute Myeloid Leukemia | A741V | Missense | 1 |
| LAML | Acute Myeloid Leukemia | C497Y | Missense | 1 |
| LAML | Acute Myeloid Leukemia | D781G | Missense | 1 |
| LAML | Acute Myeloid Leukemia | E505* | Nonsense | 1 |
| LAML | Acute Myeloid Leukemia | F909C | Missense | 1 |
| LAML | Acute Myeloid Leukemia | K468R | Missense | 1 |
| LAML | Acute Myeloid Leukemia | K829R | Missense | 1 |
| LAML | Acute Myeloid Leukemia | P718L | Missense | 1 |
| LAML | Acute Myeloid Leukemia | Q485* | Nonsense | 1 |
| LAML | Acute Myeloid Leukemia | Q515* | Nonsense | 1 |
| LAML | Acute Myeloid Leukemia | Q615* | Nonsense | 1 |
| LAML | Acute Myeloid Leukemia | R320* | Nonsense | 1 |
| LAML | Acute Myeloid Leukemia | R729Q | Missense | 1 |
| LAML | Acute Myeloid Leukemia | R729W | Missense | 1 |
| LAML | Acute Myeloid Leukemia | R792H | Missense | 1 |
| LAML | Acute Myeloid Leukemia | R882P | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A259G | Missense | 1 |
| LGG | Brain Lower Grade Glioma | C540Y | Missense | 1 |
| LGG | Brain Lower Grade Glioma | C586C | Silent | 1 |
| LGG | Brain Lower Grade Glioma | D686Y | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E545D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | F732L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | K721E | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R183W | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R484W | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R659H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | W206* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | W306* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | W893* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | A192E | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | C537F | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E545Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R379H | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R598R | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | R676W | Missense | 1 |
| LUAD | Lung adenocarcinoma | A116S | Missense | 1 |
| LUAD | Lung adenocarcinoma | C494C | Silent | 1 |
| LUAD | Lung adenocarcinoma | C494S | Missense | 1 |
| LUAD | Lung adenocarcinoma | D781H | Missense | 1 |
| LUAD | Lung adenocarcinoma | D857V | Missense | 1 |
| LUAD | Lung adenocarcinoma | E27* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E281* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E323K | Missense | 1 |
| LUAD | Lung adenocarcinoma | E463* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | F909S | Missense | 1 |
| LUAD | Lung adenocarcinoma | G413S | Missense | 1 |
| LUAD | Lung adenocarcinoma | G890C | Missense | 1 |
| LUAD | Lung adenocarcinoma | P709L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R458Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | R55H | Missense | 1 |
| LUAD | Lung adenocarcinoma | R882C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S312F | Missense | 1 |
| LUAD | Lung adenocarcinoma | S669C | Missense | 1 |
| LUAD | Lung adenocarcinoma | V258M | Missense | 1 |
| LUAD | Lung adenocarcinoma | V265V | Silent | 1 |
| LUAD | Lung adenocarcinoma | V563M | Missense | 1 |
| LUAD | Lung adenocarcinoma | W327G | Missense | 1 |
| LUAD | Lung adenocarcinoma | Y359C | Missense | 1 |
| LUAD | Lung adenocarcinoma | Y724C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G532G | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | K680R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P186P | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | Q485H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R771Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R792H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S878P | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V48V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | Y533C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | A910T | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | F414S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L737F | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P76S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A254T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A398V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | C517S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | G118R | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | P66P | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | Q615H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R790M | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | M329L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A741V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G112G | Silent | 1 |
| PRAD | Prostate adenocarcinoma | R478R | Silent | 1 |
| PRAD | Prostate adenocarcinoma | V563V | Silent | 1 |
| PRAD | Prostate adenocarcinoma | W440* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | E784* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | R209H | Missense | 1 |
| READ | Rectum adenocarcinoma | T835T | Silent | 1 |
| SARC | Sarcoma | R676W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A242A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A242V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F609F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G679G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G685E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | N797N | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P419T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P453L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P453S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q534* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R749C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Y448H | Missense | 1 |
| STAD | Stomach adenocarcinoma | A192V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A525V | Missense | 1 |
| STAD | Stomach adenocarcinoma | E205E | Silent | 1 |
| STAD | Stomach adenocarcinoma | E664D | Missense | 1 |
| STAD | Stomach adenocarcinoma | F751I | Missense | 1 |
| STAD | Stomach adenocarcinoma | G112G | Silent | 1 |
| STAD | Stomach adenocarcinoma | I490I | Silent | 1 |
| STAD | Stomach adenocarcinoma | R729W | Missense | 1 |
| STAD | Stomach adenocarcinoma | S663S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S786S | Silent | 1 |
| STAD | Stomach adenocarcinoma | Y436C | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | P777T | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | R55R | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | S62S | Silent | 1 |
| THCA | Thyroid carcinoma | P195L | Missense | 1 |
| THCA | Thyroid carcinoma | Q402* | Nonsense | 1 |
| THCA | Thyroid carcinoma | W313* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A380V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A662A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A741A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A910V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D686D | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F336V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L300P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P307S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R181H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R659H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R771Q | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 9.8 | 5.5 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 5.9 | 4.2 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 2 | 1.2 | 0 |
| COAD | Colon adenocarcinoma | 367 | 9.8 | 10.3 | 0 |
| ESCA | Esophageal carcinoma | 185 | 2 | 1.2 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 15.7 | 4.8 | 5.6 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.4 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0.6 | 5.6 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 23.6 | 27.8 |
| LGG | Brain Lower Grade Glioma | 516 | 2 | 5.5 | 16.7 |
| LIHC | Liver hepatocellular carcinoma | 373 | 2 | 3 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 3.9 | 11.5 | 16.7 |
| LUSC | Lung squamous cell carcinoma | 177 | 5.9 | 3.6 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.4 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 2 | 3.6 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0.6 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 5.9 | 0.6 | 5.6 |
| READ | Rectum adenocarcinoma | 122 | 2 | 0.6 | 5.6 |
| SARC | Sarcoma | 247 | 0 | 0.6 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 7.8 | 4.2 | 5.6 |
| STAD | Stomach adenocarcinoma | 393 | 13.7 | 3.6 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 3.9 | 0.6 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0.6 | 11.1 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 5.9 | 4.8 | 0 |