Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| PAAD | Pancreatic adenocarcinoma | G648R | Missense | 2 |
| STAD | Stomach adenocarcinoma | D172D | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | K57N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q415K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S270C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S422L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S780W | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T174A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T510R | Missense | 1 |
| BRCA | Breast invasive carcinoma | D73N | Missense | 1 |
| BRCA | Breast invasive carcinoma | E115K | Missense | 1 |
| BRCA | Breast invasive carcinoma | I747T | Missense | 1 |
| BRCA | Breast invasive carcinoma | V229V | Silent | 1 |
| COAD | Colon adenocarcinoma | D627D | Silent | 1 |
| COAD | Colon adenocarcinoma | D73D | Silent | 1 |
| COAD | Colon adenocarcinoma | D78D | Silent | 1 |
| COAD | Colon adenocarcinoma | G179V | Missense | 1 |
| COAD | Colon adenocarcinoma | G647G | Silent | 1 |
| COAD | Colon adenocarcinoma | G705G | Silent | 1 |
| COAD | Colon adenocarcinoma | P187P | Silent | 1 |
| COAD | Colon adenocarcinoma | P44L | Missense | 1 |
| COAD | Colon adenocarcinoma | P88L | Missense | 1 |
| COAD | Colon adenocarcinoma | R104* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R368R | Silent | 1 |
| COAD | Colon adenocarcinoma | R380* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R545C | Missense | 1 |
| COAD | Colon adenocarcinoma | R572S | Missense | 1 |
| COAD | Colon adenocarcinoma | R576Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R92W | Missense | 1 |
| COAD | Colon adenocarcinoma | T180T | Silent | 1 |
| COAD | Colon adenocarcinoma | V616M | Missense | 1 |
| COAD | Colon adenocarcinoma | V719A | Missense | 1 |
| COAD | Colon adenocarcinoma | V719V | Silent | 1 |
| ESCA | Esophageal carcinoma | A241A | Silent | 1 |
| ESCA | Esophageal carcinoma | K782I | Missense | 1 |
| GBM | Glioblastoma multiforme | T43T | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A514A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | C496C | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E464Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E77K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H132R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L280L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P845S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q196H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q328E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R485L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R576* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R840Q | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q415K | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P203P | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R122G | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | W694C | Missense | 1 |
| LAML | Acute Myeloid Leukemia | R538C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A585V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P44P | Silent | 1 |
| LGG | Brain Lower Grade Glioma | P529L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R840* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | T84S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T180M | Missense | 1 |
| LUAD | Lung adenocarcinoma | F462F | Silent | 1 |
| LUAD | Lung adenocarcinoma | G614V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G737C | Missense | 1 |
| LUAD | Lung adenocarcinoma | L22P | Missense | 1 |
| LUAD | Lung adenocarcinoma | P718S | Missense | 1 |
| LUAD | Lung adenocarcinoma | R122C | Missense | 1 |
| LUAD | Lung adenocarcinoma | R661W | Missense | 1 |
| LUAD | Lung adenocarcinoma | R731T | Missense | 1 |
| LUAD | Lung adenocarcinoma | S153L | Missense | 1 |
| LUAD | Lung adenocarcinoma | V229V | Silent | 1 |
| LUAD | Lung adenocarcinoma | W260S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G347D | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L768L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | R363H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S195I | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | A241A | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | C403W | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | V719L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | N352T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R573W | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | V625M | Missense | 1 |
| PRAD | Prostate adenocarcinoma | F549L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G129G | Silent | 1 |
| PRAD | Prostate adenocarcinoma | G648R | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R539Q | Missense | 1 |
| PRAD | Prostate adenocarcinoma | V296I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | V60A | Missense | 1 |
| READ | Rectum adenocarcinoma | A421T | Missense | 1 |
| READ | Rectum adenocarcinoma | A612T | Missense | 1 |
| READ | Rectum adenocarcinoma | D33N | Missense | 1 |
| READ | Rectum adenocarcinoma | L449L | Silent | 1 |
| READ | Rectum adenocarcinoma | R299Q | Missense | 1 |
| READ | Rectum adenocarcinoma | R92W | Missense | 1 |
| SARC | Sarcoma | L228R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E175E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F140F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G687D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H132Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P141S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P240L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P565S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P845S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R106* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R106L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R106R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R538R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R576* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R840* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | S123S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S183N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S778L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V818M | Missense | 1 |
| STAD | Stomach adenocarcinoma | A513A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A585V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A660A | Silent | 1 |
| STAD | Stomach adenocarcinoma | F696L | Missense | 1 |
| STAD | Stomach adenocarcinoma | I781I | Silent | 1 |
| STAD | Stomach adenocarcinoma | P240P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P529P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P568P | Silent | 1 |
| STAD | Stomach adenocarcinoma | R312* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R398H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R537W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R545H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R571Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R573W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R576* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R712Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R97C | Missense | 1 |
| STAD | Stomach adenocarcinoma | S34S | Silent | 1 |
| STAD | Stomach adenocarcinoma | V602I | Missense | 1 |
| STAD | Stomach adenocarcinoma | W335R | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | R537W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D627N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E806G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G511D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G74G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L146L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R106Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R299* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R380* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R380Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R417* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R537W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R95R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S51P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S780S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T180T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T493M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T71A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V229M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 7.1 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 2.4 | 3.1 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 21.4 | 9.2 | 16.7 |
| ESCA | Esophageal carcinoma | 185 | 2.4 | 1 | 0 |
| GBM | Glioblastoma multiforme | 283 | 2.4 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 7.1 | 8.2 | 8.3 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 2.4 | 2 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 1 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 2.4 | 3.1 | 8.3 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 4.8 | 9.2 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 2.4 | 3.1 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2.4 | 2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 5.1 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 2.4 | 5.1 | 0 |
| READ | Rectum adenocarcinoma | 122 | 2.4 | 5.1 | 0 |
| SARC | Sarcoma | 247 | 0 | 1 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 11.9 | 10.2 | 25 |
| STAD | Stomach adenocarcinoma | 393 | 21.4 | 11.2 | 16.7 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 11.9 | 10.2 | 25 |