Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | D239N | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A270A | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | D226N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E10Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q318H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R47Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S26* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | V364V | Silent | 1 |
| BRCA | Breast invasive carcinoma | V285L | Missense | 1 |
| CESC | Cervical and endocervical cancers | E197Q | Missense | 1 |
| COAD | Colon adenocarcinoma | A2A | Silent | 1 |
| COAD | Colon adenocarcinoma | K43E | Missense | 1 |
| COAD | Colon adenocarcinoma | P183S | Missense | 1 |
| ESCA | Esophageal carcinoma | A320T | Missense | 1 |
| GBM | Glioblastoma multiforme | A74T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P310S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R47* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S325N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A356V | Missense | 1 |
| LUAD | Lung adenocarcinoma | A244T | Missense | 1 |
| LUAD | Lung adenocarcinoma | D16N | Missense | 1 |
| LUAD | Lung adenocarcinoma | D82N | Missense | 1 |
| LUAD | Lung adenocarcinoma | E234D | Missense | 1 |
| LUAD | Lung adenocarcinoma | K133M | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q351K | Missense | 1 |
| LUAD | Lung adenocarcinoma | R254S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | F261L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P215R | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A347T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | N139K | Missense | 1 |
| READ | Rectum adenocarcinoma | L240I | Missense | 1 |
| SARC | Sarcoma | D231N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A298S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A83A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E293K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E340K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F238F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F301F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G275S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G70R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L125L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L369L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | M15I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | N110Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P247L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S148S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S28F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S28S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S353S | Silent | 1 |
| STAD | Stomach adenocarcinoma | A83V | Missense | 1 |
| STAD | Stomach adenocarcinoma | E233D | Missense | 1 |
| STAD | Stomach adenocarcinoma | G315R | Missense | 1 |
| STAD | Stomach adenocarcinoma | G91R | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q93K | Missense | 1 |
| STAD | Stomach adenocarcinoma | R47* | Nonsense | 1 |
| TGCT | Testicular Germ Cell Tumors | Q60* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L369I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N48D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T204M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y242Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 16.7 | 8.9 | 25 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 2.2 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.2 | 0 |
| COAD | Colon adenocarcinoma | 367 | 8.3 | 4.4 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 2.2 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 4.4 | 25 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2.2 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 15.6 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 4.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.2 | 0 |
| SARC | Sarcoma | 247 | 0 | 2.2 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 66.7 | 24.4 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 11.1 | 25 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 25 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 8.3 | 6.7 | 0 |