Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | C298Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D279Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E255Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G215* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | G215V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | M354I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R221* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | T125P | Missense | 1 |
| BRCA | Breast invasive carcinoma | I325I | Silent | 1 |
| BRCA | Breast invasive carcinoma | P359P | Silent | 1 |
| COAD | Colon adenocarcinoma | A193A | Silent | 1 |
| COAD | Colon adenocarcinoma | A76S | Missense | 1 |
| COAD | Colon adenocarcinoma | E337G | Missense | 1 |
| COAD | Colon adenocarcinoma | K328T | Missense | 1 |
| COAD | Colon adenocarcinoma | P359P | Silent | 1 |
| COAD | Colon adenocarcinoma | R321S | Missense | 1 |
| COAD | Colon adenocarcinoma | R84* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | S254Y | Missense | 1 |
| COAD | Colon adenocarcinoma | T310T | Silent | 1 |
| ESCA | Esophageal carcinoma | Y209C | Missense | 1 |
| GBM | Glioblastoma multiforme | R38H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H61N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L357L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R124C | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G265G | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L233L | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Q45E | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R77W | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Y272H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A153V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | H227Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R179H | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R350G | Missense | 1 |
| LUAD | Lung adenocarcinoma | D126D | Silent | 1 |
| LUAD | Lung adenocarcinoma | D349N | Missense | 1 |
| LUAD | Lung adenocarcinoma | E203* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E291* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E58V | Missense | 1 |
| LUAD | Lung adenocarcinoma | H230Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | P289L | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q323P | Missense | 1 |
| LUAD | Lung adenocarcinoma | S68S | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | D279E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E22E | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | K318N | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | A76D | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | G238G | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R321H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | T310I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | T46T | Silent | 1 |
| READ | Rectum adenocarcinoma | C371S | Missense | 1 |
| READ | Rectum adenocarcinoma | H303Y | Missense | 1 |
| SARC | Sarcoma | P136L | Missense | 1 |
| SARC | Sarcoma | R137* | Nonsense | 1 |
| SARC | Sarcoma | S200C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P136S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P249S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S336F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S383S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S94F | Missense | 1 |
| STAD | Stomach adenocarcinoma | A315V | Missense | 1 |
| STAD | Stomach adenocarcinoma | L373M | Missense | 1 |
| STAD | Stomach adenocarcinoma | R152* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | Y72Y | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D19Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E6D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L106M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R124H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R131* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R30C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R350C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y320C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 12.2 | 25 |
| BRCA | Breast invasive carcinoma | 976 | 13.3 | 0 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 20 | 10.2 | 12.5 |
| ESCA | Esophageal carcinoma | 185 | 0 | 2 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.7 | 4.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 6.7 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 6.7 | 6.1 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 6.1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 13.3 | 10.2 | 25 |
| LUSC | Lung squamous cell carcinoma | 177 | 6.7 | 4.1 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 6.7 | 4.1 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 6.7 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 4.1 | 0 |
| SARC | Sarcoma | 247 | 0 | 4.1 | 12.5 |
| SKCM | Skin Cutaneous Melanoma | 290 | 6.7 | 8.2 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 6.7 | 4.1 | 12.5 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 14.3 | 12.5 |