Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| LIHC | Liver hepatocellular carcinoma | S237F | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | R210* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | E154K | Missense | 1 |
| CESC | Cervical and endocervical cancers | Q45* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | C284C | Silent | 1 |
| COAD | Colon adenocarcinoma | T235N | Missense | 1 |
| COAD | Colon adenocarcinoma | V199I | Missense | 1 |
| COAD | Colon adenocarcinoma | V199V | Silent | 1 |
| ESCA | Esophageal carcinoma | K169T | Missense | 1 |
| ESCA | Esophageal carcinoma | L222M | Missense | 1 |
| ESCA | Esophageal carcinoma | P252P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A218A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I139M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S179F | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | M271V | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | N52T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E226D | Missense | 1 |
| LUAD | Lung adenocarcinoma | A133V | Missense | 1 |
| LUAD | Lung adenocarcinoma | A76P | Missense | 1 |
| LUAD | Lung adenocarcinoma | C284C | Silent | 1 |
| LUAD | Lung adenocarcinoma | D286Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | E159G | Missense | 1 |
| LUAD | Lung adenocarcinoma | G181R | Missense | 1 |
| LUAD | Lung adenocarcinoma | G267G | Silent | 1 |
| LUAD | Lung adenocarcinoma | P258H | Missense | 1 |
| LUAD | Lung adenocarcinoma | P8P | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | A67D | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | I55M | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q15* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | R175W | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S29S | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | R80H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | K208T | Missense | 1 |
| READ | Rectum adenocarcinoma | A188T | Missense | 1 |
| READ | Rectum adenocarcinoma | E159D | Missense | 1 |
| SARC | Sarcoma | G155G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D253N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E141K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G155G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | N151N | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R177C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R94W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Y72C | Missense | 1 |
| STAD | Stomach adenocarcinoma | A285T | Missense | 1 |
| STAD | Stomach adenocarcinoma | D228N | Missense | 1 |
| STAD | Stomach adenocarcinoma | R277Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R289H | Missense | 1 |
| STAD | Stomach adenocarcinoma | V127A | Missense | 1 |
| STAD | Stomach adenocarcinoma | V199A | Missense | 1 |
| THCA | Thyroid carcinoma | G69D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D195N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E159E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G251G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H186H | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I142V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K167N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R168Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S138I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V37M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 0 | 33.3 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 0 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.3 | 33.3 |
| COAD | Colon adenocarcinoma | 367 | 14.3 | 4.7 | 0 |
| ESCA | Esophageal carcinoma | 185 | 7.1 | 4.7 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 7.1 | 4.7 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.3 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.3 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2.3 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 4.7 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 21.4 | 14 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 7.1 | 7 | 33.3 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.3 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.3 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 4.7 | 0 |
| SARC | Sarcoma | 247 | 7.1 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 14.3 | 11.6 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 14 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 2.3 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 21.4 | 14 | 0 |