Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | V206A | Missense | 4 |
| BLCA | Bladder urothelial carcinoma | E215K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E239K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K221N | Missense | 1 |
| BRCA | Breast invasive carcinoma | G199S | Missense | 1 |
| BRCA | Breast invasive carcinoma | T337T | Silent | 1 |
| CESC | Cervical and endocervical cancers | L203F | Missense | 1 |
| COAD | Colon adenocarcinoma | F285Y | Missense | 1 |
| COAD | Colon adenocarcinoma | R331* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q307K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S137R | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S235S | Silent | 1 |
| LAML | Acute Myeloid Leukemia | N351S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A353V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S137R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T276T | Silent | 1 |
| LUAD | Lung adenocarcinoma | I268I | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | V206I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | V343I | Missense | 1 |
| READ | Rectum adenocarcinoma | V206A | Missense | 1 |
| SARC | Sarcoma | T333T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P142P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P324L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q358Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Y218Y | Silent | 1 |
| STAD | Stomach adenocarcinoma | A325T | Missense | 1 |
| STAD | Stomach adenocarcinoma | C367* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | L183L | Silent | 1 |
| STAD | Stomach adenocarcinoma | L354P | Missense | 1 |
| STAD | Stomach adenocarcinoma | T350T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P315P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S352R | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 13.6 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 9.1 | 4.5 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 4.5 | 0 |
| COAD | Colon adenocarcinoma | 367 | 0 | 22.7 | 50 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 9.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 9.1 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 4.5 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 4.5 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 9.1 | 4.5 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 9.1 | 0 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 0 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 4.5 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 4.5 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 4.5 | 0 |
| SARC | Sarcoma | 247 | 9.1 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 27.3 | 4.5 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 18.2 | 9.1 | 50 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.1 | 4.5 | 0 |