Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| UCEC | Uterine Corpus Endometrial Carcinoma | R269I | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A11A | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L260F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | M270I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | M271L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R441P | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S75* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | D142N | Missense | 1 |
| BRCA | Breast invasive carcinoma | I251T | Missense | 1 |
| BRCA | Breast invasive carcinoma | K77R | Missense | 1 |
| BRCA | Breast invasive carcinoma | R355Q | Missense | 1 |
| COAD | Colon adenocarcinoma | L391S | Missense | 1 |
| COAD | Colon adenocarcinoma | P110P | Silent | 1 |
| COAD | Colon adenocarcinoma | W373* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | N58K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A273A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q292* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R52H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | W263R | Missense | 1 |
| LAML | Acute Myeloid Leukemia | L196Q | Missense | 1 |
| LAML | Acute Myeloid Leukemia | S75* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | D257N | Missense | 1 |
| LUAD | Lung adenocarcinoma | A411P | Missense | 1 |
| LUAD | Lung adenocarcinoma | G117V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G170V | Missense | 1 |
| LUAD | Lung adenocarcinoma | I319L | Missense | 1 |
| LUAD | Lung adenocarcinoma | K322E | Missense | 1 |
| LUAD | Lung adenocarcinoma | L240V | Missense | 1 |
| LUAD | Lung adenocarcinoma | M376I | Missense | 1 |
| LUAD | Lung adenocarcinoma | T48A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | F372L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | W263L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | C150C | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | I363V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | K335Q | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G380G | Silent | 1 |
| PRAD | Prostate adenocarcinoma | V187G | Missense | 1 |
| READ | Rectum adenocarcinoma | G170G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H92Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P161L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R441* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | F113L | Missense | 1 |
| STAD | Stomach adenocarcinoma | G316G | Silent | 1 |
| STAD | Stomach adenocarcinoma | R313* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R355* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | V232A | Missense | 1 |
| THCA | Thyroid carcinoma | G35E | Missense | 1 |
| THCA | Thyroid carcinoma | I251V | Missense | 1 |
| THYM | Thymoma | Y308C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A41T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D317N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D40D | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E107K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L225V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L377I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | M271I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P203T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R441* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R441Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S359S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T179A | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 11.1 | 8.9 | 12.5 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 8.9 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 11.1 | 2.2 | 12.5 |
| ESCA | Esophageal carcinoma | 185 | 0 | 2.2 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 11.1 | 4.4 | 12.5 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 2.2 | 12.5 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 2.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 17.8 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 11.1 | 4.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 11.1 | 2.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 11.1 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 0 | 4.4 | 12.5 |
| STAD | Stomach adenocarcinoma | 393 | 11.1 | 4.4 | 25 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 4.4 | 0 |
| THYM | Thymoma | 119 | 0 | 2.2 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 22.2 | 24.4 | 12.5 |