Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| READ | Rectum adenocarcinoma | R282H | Missense | 2 |
| STAD | Stomach adenocarcinoma | A17D | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D57N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1010Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1201Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E482K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E630K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G233V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I790I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L647L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P563A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R1191H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R652Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S246L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S379L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S752S | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | V726L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V727V | Silent | 1 |
| BRCA | Breast invasive carcinoma | A635T | Missense | 1 |
| BRCA | Breast invasive carcinoma | H730P | Missense | 1 |
| BRCA | Breast invasive carcinoma | H970P | Missense | 1 |
| BRCA | Breast invasive carcinoma | N528Y | Missense | 1 |
| BRCA | Breast invasive carcinoma | P196T | Missense | 1 |
| CESC | Cervical and endocervical cancers | A631A | Silent | 1 |
| CESC | Cervical and endocervical cancers | D1143H | Missense | 1 |
| CESC | Cervical and endocervical cancers | I1107I | Silent | 1 |
| CESC | Cervical and endocervical cancers | K131K | Silent | 1 |
| CESC | Cervical and endocervical cancers | S609F | Missense | 1 |
| CESC | Cervical and endocervical cancers | W1024C | Missense | 1 |
| COAD | Colon adenocarcinoma | E545D | Missense | 1 |
| COAD | Colon adenocarcinoma | G940S | Missense | 1 |
| COAD | Colon adenocarcinoma | H491N | Missense | 1 |
| COAD | Colon adenocarcinoma | H850R | Missense | 1 |
| COAD | Colon adenocarcinoma | R106Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R245C | Missense | 1 |
| COAD | Colon adenocarcinoma | V621M | Missense | 1 |
| ESCA | Esophageal carcinoma | N963K | Missense | 1 |
| ESCA | Esophageal carcinoma | P594T | Missense | 1 |
| ESCA | Esophageal carcinoma | R514C | Missense | 1 |
| ESCA | Esophageal carcinoma | V1208V | Silent | 1 |
| GBM | Glioblastoma multiforme | A900V | Missense | 1 |
| GBM | Glioblastoma multiforme | I1182I | Silent | 1 |
| GBM | Glioblastoma multiforme | R518C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A461V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E261G | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E450D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K226I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L1205L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M737I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P117L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P534L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R46C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V531V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q660R | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R1132Q | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A23S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | T853I | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A1181V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | G1069G | Silent | 1 |
| LGG | Brain Lower Grade Glioma | G398E | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T252M | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | D1078D | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | E1016G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K1176R | Missense | 1 |
| LUAD | Lung adenocarcinoma | A1137T | Missense | 1 |
| LUAD | Lung adenocarcinoma | A635S | Missense | 1 |
| LUAD | Lung adenocarcinoma | E311Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | F649L | Missense | 1 |
| LUAD | Lung adenocarcinoma | L298V | Missense | 1 |
| LUAD | Lung adenocarcinoma | L400L | Silent | 1 |
| LUAD | Lung adenocarcinoma | M210I | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1012P | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q580K | Missense | 1 |
| LUAD | Lung adenocarcinoma | R31T | Missense | 1 |
| LUAD | Lung adenocarcinoma | R644R | Silent | 1 |
| LUAD | Lung adenocarcinoma | R807R | Silent | 1 |
| LUAD | Lung adenocarcinoma | S619L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L705L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | S65* | Nonsense | 1 |
| OV | Ovarian serous cystadenocarcinoma | E77D | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S119F | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | C987C | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | F1015F | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | P892P | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R802H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | T250I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A1020V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | N1018K | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R894H | Missense | 1 |
| READ | Rectum adenocarcinoma | R740C | Missense | 1 |
| SARC | Sarcoma | A486T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A157A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E955E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P202L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P202P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P549S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P557L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P573H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P651S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P892S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q158* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R905S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S525S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S872L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V387V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Y1097Y | Silent | 1 |
| STAD | Stomach adenocarcinoma | A900V | Missense | 1 |
| STAD | Stomach adenocarcinoma | G105G | Silent | 1 |
| STAD | Stomach adenocarcinoma | I667I | Silent | 1 |
| STAD | Stomach adenocarcinoma | K906M | Missense | 1 |
| STAD | Stomach adenocarcinoma | L632L | Silent | 1 |
| STAD | Stomach adenocarcinoma | R1135H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1145Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R347* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R347Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R629Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R917H | Missense | 1 |
| STAD | Stomach adenocarcinoma | V376V | Silent | 1 |
| STAD | Stomach adenocarcinoma | Y1043C | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y952C | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | P198T | Missense | 1 |
| THCA | Thyroid carcinoma | R1188L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D332A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T221T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T959M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 12.5 | 13 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 5.4 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 9.4 | 3.3 | 0 |
| COAD | Colon adenocarcinoma | 367 | 0 | 7.6 | 0 |
| ESCA | Esophageal carcinoma | 185 | 3.1 | 3.3 | 0 |
| GBM | Glioblastoma multiforme | 283 | 3.1 | 2.2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.2 | 8.7 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.2 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.2 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 3.1 | 3.3 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.1 | 2.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 12.5 | 9.8 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 3.1 | 0 | 33.3 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 9.4 | 2.2 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 3.3 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 3.3 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.1 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 18.8 | 8.7 | 33.3 |
| STAD | Stomach adenocarcinoma | 393 | 12.5 | 12 | 33.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.1 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.1 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 3.1 | 2.2 | 0 |