Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | H732Y | Missense | 3 |
| BLCA | Bladder urothelial carcinoma | A604T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D114H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D327N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D430N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D542N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G44R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | N422S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R221P | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R532W | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S509F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V494F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V647L | Missense | 1 |
| BRCA | Breast invasive carcinoma | A470D | Missense | 1 |
| BRCA | Breast invasive carcinoma | A832V | Missense | 1 |
| BRCA | Breast invasive carcinoma | G638V | Missense | 1 |
| BRCA | Breast invasive carcinoma | K258K | Silent | 1 |
| BRCA | Breast invasive carcinoma | N82S | Missense | 1 |
| BRCA | Breast invasive carcinoma | P353H | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q309H | Missense | 1 |
| CESC | Cervical and endocervical cancers | A654T | Missense | 1 |
| CESC | Cervical and endocervical cancers | A662V | Missense | 1 |
| CESC | Cervical and endocervical cancers | R243Q | Missense | 1 |
| COAD | Colon adenocarcinoma | D277N | Missense | 1 |
| COAD | Colon adenocarcinoma | H732R | Missense | 1 |
| COAD | Colon adenocarcinoma | I101V | Missense | 1 |
| COAD | Colon adenocarcinoma | L241I | Missense | 1 |
| COAD | Colon adenocarcinoma | L361P | Missense | 1 |
| COAD | Colon adenocarcinoma | Q605Q | Silent | 1 |
| COAD | Colon adenocarcinoma | Q63R | Missense | 1 |
| COAD | Colon adenocarcinoma | R243* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | V679E | Missense | 1 |
| COAD | Colon adenocarcinoma | Y231Y | Silent | 1 |
| ESCA | Esophageal carcinoma | I772V | Missense | 1 |
| ESCA | Esophageal carcinoma | M485I | Missense | 1 |
| ESCA | Esophageal carcinoma | T446T | Silent | 1 |
| GBM | Glioblastoma multiforme | K322E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V125V | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A110S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | G276A | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | T503S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A359A | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | R199* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | T746S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Y115C | Missense | 1 |
| LUAD | Lung adenocarcinoma | A559V | Missense | 1 |
| LUAD | Lung adenocarcinoma | N365S | Missense | 1 |
| LUAD | Lung adenocarcinoma | P77P | Silent | 1 |
| LUAD | Lung adenocarcinoma | R214H | Missense | 1 |
| LUAD | Lung adenocarcinoma | R756Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | S472L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S488L | Missense | 1 |
| LUAD | Lung adenocarcinoma | T505I | Missense | 1 |
| LUAD | Lung adenocarcinoma | T714M | Missense | 1 |
| LUAD | Lung adenocarcinoma | V664V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | D206N | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | H732P | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L361M | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | N205H | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R239R | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | S284C | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L651F | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R224H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R775* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | S2G | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S807Y | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P346S | Missense | 1 |
| SARC | Sarcoma | P292S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I282I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I89M | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L331F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P353L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R779K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S700N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S800F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T740A | Missense | 1 |
| STAD | Stomach adenocarcinoma | A350T | Missense | 1 |
| STAD | Stomach adenocarcinoma | I682I | Silent | 1 |
| STAD | Stomach adenocarcinoma | R199* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R450G | Missense | 1 |
| STAD | Stomach adenocarcinoma | S390L | Missense | 1 |
| STAD | Stomach adenocarcinoma | T420A | Missense | 1 |
| STAD | Stomach adenocarcinoma | T746T | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | A349V | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | R458R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A792V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K195K | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L536L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L544L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R224H | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 16.7 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 6.2 | 8.3 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 4.2 | 0 |
| COAD | Colon adenocarcinoma | 367 | 12.5 | 13.9 | 25 |
| ESCA | Esophageal carcinoma | 185 | 6.2 | 2.8 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.4 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.2 | 0 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 4.2 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 6.2 | 2.8 | 25 |
| LUAD | Lung adenocarcinoma | 533 | 12.5 | 11.1 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 1.4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 6.2 | 5.6 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 5.6 | 25 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.4 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.4 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 6.2 | 9.7 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 12.5 | 5.6 | 25 |
| TGCT | Testicular Germ Cell Tumors | 147 | 6.2 | 1.4 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 18.8 | 2.8 | 0 |