Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | E270G | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E147Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E49K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K69T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R243T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R524Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | E581E | Silent | 1 |
| BRCA | Breast invasive carcinoma | K95N | Missense | 1 |
| BRCA | Breast invasive carcinoma | R145K | Missense | 1 |
| CESC | Cervical and endocervical cancers | H102D | Missense | 1 |
| COAD | Colon adenocarcinoma | A599A | Silent | 1 |
| COAD | Colon adenocarcinoma | A599V | Missense | 1 |
| COAD | Colon adenocarcinoma | A711T | Missense | 1 |
| COAD | Colon adenocarcinoma | E270E | Silent | 1 |
| COAD | Colon adenocarcinoma | H787H | Silent | 1 |
| COAD | Colon adenocarcinoma | I134N | Missense | 1 |
| COAD | Colon adenocarcinoma | L275L | Silent | 1 |
| COAD | Colon adenocarcinoma | L565V | Missense | 1 |
| COAD | Colon adenocarcinoma | R531M | Missense | 1 |
| COAD | Colon adenocarcinoma | R749Q | Missense | 1 |
| ESCA | Esophageal carcinoma | D463Y | Missense | 1 |
| ESCA | Esophageal carcinoma | R238K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D118E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P388P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q62R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S538C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T215A | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E281D | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R434M | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V268D | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V73I | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E788K | Missense | 1 |
| LGG | Brain Lower Grade Glioma | L323L | Silent | 1 |
| LGG | Brain Lower Grade Glioma | T467T | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | E542D | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V268F | Missense | 1 |
| LUAD | Lung adenocarcinoma | H702L | Missense | 1 |
| LUAD | Lung adenocarcinoma | L302R | Missense | 1 |
| LUAD | Lung adenocarcinoma | M683I | Missense | 1 |
| LUAD | Lung adenocarcinoma | N361H | Missense | 1 |
| LUAD | Lung adenocarcinoma | R403L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S688I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D227H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q602L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | A599S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A560T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A563V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | H732R | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | T257A | Missense | 1 |
| PRAD | Prostate adenocarcinoma | L382W | Missense | 1 |
| READ | Rectum adenocarcinoma | E270G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A416A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D427E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H263H | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H263L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H307Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L428M | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | N496K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R221* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R412C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R464Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S680F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S754L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T567T | Silent | 1 |
| STAD | Stomach adenocarcinoma | I191T | Missense | 1 |
| STAD | Stomach adenocarcinoma | N786S | Missense | 1 |
| STAD | Stomach adenocarcinoma | S754L | Missense | 1 |
| STAD | Stomach adenocarcinoma | V155A | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | Q138L | Missense | 1 |
| THCA | Thyroid carcinoma | V557V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C313R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E424E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R332C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S349F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T500I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V73G | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 7.9 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 7.7 | 3.2 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.6 | 0 |
| COAD | Colon adenocarcinoma | 367 | 30.8 | 12.7 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 3.2 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 7.7 | 6.3 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 6.3 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 15.4 | 1.6 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 3.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 9.5 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 3.2 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.6 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 6.3 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.6 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.6 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 23.1 | 14.3 | 100 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 6.3 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.6 | 0 |
| THCA | Thyroid carcinoma | 495 | 7.7 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 7.7 | 7.9 | 0 |