Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | E1119G | Missense | 2 |
| COAD | Colon adenocarcinoma | R652Q | Missense | 2 |
| COAD | Colon adenocarcinoma | V780I | Missense | 2 |
| READ | Rectum adenocarcinoma | R1038G | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A1293T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | A64T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | C17Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D1442V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G410S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K1207N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L1091F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L549L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L660I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q1041* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q254Q | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q79* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R1467Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S687W | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S813F | Missense | 1 |
| BRCA | Breast invasive carcinoma | D1248Y | Missense | 1 |
| BRCA | Breast invasive carcinoma | D209H | Missense | 1 |
| BRCA | Breast invasive carcinoma | E1170E | Silent | 1 |
| BRCA | Breast invasive carcinoma | E272K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E403K | Missense | 1 |
| BRCA | Breast invasive carcinoma | G537D | Missense | 1 |
| BRCA | Breast invasive carcinoma | H1398P | Missense | 1 |
| BRCA | Breast invasive carcinoma | I240I | Silent | 1 |
| BRCA | Breast invasive carcinoma | K324K | Silent | 1 |
| BRCA | Breast invasive carcinoma | K979E | Missense | 1 |
| BRCA | Breast invasive carcinoma | L673L | Silent | 1 |
| BRCA | Breast invasive carcinoma | P307A | Missense | 1 |
| BRCA | Breast invasive carcinoma | P823T | Missense | 1 |
| BRCA | Breast invasive carcinoma | P896S | Missense | 1 |
| BRCA | Breast invasive carcinoma | R767H | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1146T | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1345L | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1380L | Missense | 1 |
| BRCA | Breast invasive carcinoma | Y882S | Missense | 1 |
| CESC | Cervical and endocervical cancers | D103D | Silent | 1 |
| CESC | Cervical and endocervical cancers | E272K | Missense | 1 |
| CESC | Cervical and endocervical cancers | M229I | Missense | 1 |
| CESC | Cervical and endocervical cancers | R327H | Missense | 1 |
| CESC | Cervical and endocervical cancers | S1027* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | A1290S | Missense | 1 |
| COAD | Colon adenocarcinoma | D869G | Missense | 1 |
| COAD | Colon adenocarcinoma | D989Y | Missense | 1 |
| COAD | Colon adenocarcinoma | E1119* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | E1175K | Missense | 1 |
| COAD | Colon adenocarcinoma | E1283G | Missense | 1 |
| COAD | Colon adenocarcinoma | E257D | Missense | 1 |
| COAD | Colon adenocarcinoma | E495K | Missense | 1 |
| COAD | Colon adenocarcinoma | G1443D | Missense | 1 |
| COAD | Colon adenocarcinoma | G1484R | Missense | 1 |
| COAD | Colon adenocarcinoma | K820N | Missense | 1 |
| COAD | Colon adenocarcinoma | L1401L | Silent | 1 |
| COAD | Colon adenocarcinoma | N902I | Missense | 1 |
| COAD | Colon adenocarcinoma | P591P | Silent | 1 |
| COAD | Colon adenocarcinoma | P591Q | Missense | 1 |
| COAD | Colon adenocarcinoma | P677L | Missense | 1 |
| COAD | Colon adenocarcinoma | Q1014H | Missense | 1 |
| COAD | Colon adenocarcinoma | Q524* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R1038K | Missense | 1 |
| COAD | Colon adenocarcinoma | R1053H | Missense | 1 |
| COAD | Colon adenocarcinoma | R327H | Missense | 1 |
| COAD | Colon adenocarcinoma | S708S | Silent | 1 |
| COAD | Colon adenocarcinoma | V449M | Missense | 1 |
| COAD | Colon adenocarcinoma | V785D | Missense | 1 |
| ESCA | Esophageal carcinoma | A87T | Missense | 1 |
| ESCA | Esophageal carcinoma | H641Q | Missense | 1 |
| ESCA | Esophageal carcinoma | L883L | Silent | 1 |
| ESCA | Esophageal carcinoma | Q1041Q | Silent | 1 |
| ESCA | Esophageal carcinoma | R479C | Missense | 1 |
| GBM | Glioblastoma multiforme | K1359E | Missense | 1 |
| GBM | Glioblastoma multiforme | L700S | Missense | 1 |
| GBM | Glioblastoma multiforme | M713I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A279T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A306S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D1249V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D1426H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E647K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K1184E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M752I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P677P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V1262M | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | C143W | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E1145K | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | K415K | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | L697L | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q244H | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | N560S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R915Q | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | T1347T | Silent | 1 |
| LGG | Brain Lower Grade Glioma | A1275A | Silent | 1 |
| LGG | Brain Lower Grade Glioma | A1391V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | Q1438R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G695V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | H598R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R338W | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T905T | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | W589* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | D401G | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1003Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1070K | Missense | 1 |
| LUAD | Lung adenocarcinoma | E91Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | F996L | Missense | 1 |
| LUAD | Lung adenocarcinoma | G531A | Missense | 1 |
| LUAD | Lung adenocarcinoma | L1405L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L228L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L868L | Silent | 1 |
| LUAD | Lung adenocarcinoma | M245I | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1202L | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1349Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | P253R | Missense | 1 |
| LUAD | Lung adenocarcinoma | P305P | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q1462L | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q706L | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q79H | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1335S | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1396G | Missense | 1 |
| LUAD | Lung adenocarcinoma | R735* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | R945L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S1381S | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L697F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R319T | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | T1135T | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | Q524* | Nonsense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R557G | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | W581* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | A1215T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | C1034Y | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | F1256L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | N1126S | Missense | 1 |
| PRAD | Prostate adenocarcinoma | H1268H | Silent | 1 |
| PRAD | Prostate adenocarcinoma | I6I | Silent | 1 |
| PRAD | Prostate adenocarcinoma | P22R | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R1467* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | E1119G | Missense | 1 |
| READ | Rectum adenocarcinoma | K1487K | Silent | 1 |
| READ | Rectum adenocarcinoma | K186R | Missense | 1 |
| READ | Rectum adenocarcinoma | R1404C | Missense | 1 |
| READ | Rectum adenocarcinoma | S1139F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E14K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F1056F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F779F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F812I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G1219E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H210Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L1458L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L566L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L597L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L610L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L621S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L811L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P740L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P7P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P990S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R122C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R612* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | S121R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S57F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S708F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S782F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T667T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V1366V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | W835* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | A1113T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A211T | Missense | 1 |
| STAD | Stomach adenocarcinoma | D386D | Silent | 1 |
| STAD | Stomach adenocarcinoma | D639D | Silent | 1 |
| STAD | Stomach adenocarcinoma | D736D | Silent | 1 |
| STAD | Stomach adenocarcinoma | E784D | Missense | 1 |
| STAD | Stomach adenocarcinoma | E946D | Missense | 1 |
| STAD | Stomach adenocarcinoma | G1410R | Missense | 1 |
| STAD | Stomach adenocarcinoma | G456E | Missense | 1 |
| STAD | Stomach adenocarcinoma | G53R | Missense | 1 |
| STAD | Stomach adenocarcinoma | G601S | Missense | 1 |
| STAD | Stomach adenocarcinoma | G952G | Silent | 1 |
| STAD | Stomach adenocarcinoma | H210H | Silent | 1 |
| STAD | Stomach adenocarcinoma | I31V | Missense | 1 |
| STAD | Stomach adenocarcinoma | I951L | Missense | 1 |
| STAD | Stomach adenocarcinoma | K1210T | Missense | 1 |
| STAD | Stomach adenocarcinoma | K1258N | Missense | 1 |
| STAD | Stomach adenocarcinoma | K258E | Missense | 1 |
| STAD | Stomach adenocarcinoma | L859L | Silent | 1 |
| STAD | Stomach adenocarcinoma | L883L | Silent | 1 |
| STAD | Stomach adenocarcinoma | N807N | Silent | 1 |
| STAD | Stomach adenocarcinoma | P22H | Missense | 1 |
| STAD | Stomach adenocarcinoma | P66L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1053C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R735* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | S1098S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S1099N | Missense | 1 |
| STAD | Stomach adenocarcinoma | T587M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V127I | Missense | 1 |
| STAD | Stomach adenocarcinoma | V709I | Missense | 1 |
| THCA | Thyroid carcinoma | K323R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A294T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A62T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1423* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E272K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E326D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E373D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K849N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L682R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q953H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1087Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1221Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1288Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1404H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R787K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R803I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1146I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S135S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S893* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T144M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T914T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V733A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | W851L | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 4.2 | 6.9 | 13.3 |
| BRCA | Breast invasive carcinoma | 976 | 8.3 | 9.4 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 2.1 | 1.9 | 6.7 |
| COAD | Colon adenocarcinoma | 367 | 6.2 | 15.7 | 13.3 |
| ESCA | Esophageal carcinoma | 185 | 4.2 | 1.9 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.9 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 2.1 | 5 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 4.2 | 1.9 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 2.1 | 1.3 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 2.1 | 1.3 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 2.1 | 1.9 | 6.7 |
| LUAD | Lung adenocarcinoma | 533 | 10.4 | 10.1 | 6.7 |
| LUSC | Lung squamous cell carcinoma | 177 | 2.1 | 1.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0.6 | 13.3 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.5 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 4.2 | 0.6 | 6.7 |
| READ | Rectum adenocarcinoma | 122 | 2.1 | 3.8 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 20.8 | 7.5 | 13.3 |
| STAD | Stomach adenocarcinoma | 393 | 18.8 | 12.6 | 6.7 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0.6 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 4.2 | 11.3 | 13.3 |