Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | G247G | Silent | 2 |
| SKCM | Skin Cutaneous Melanoma | S98F | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | W30* | Nonsense | 2 |
| STAD | Stomach adenocarcinoma | R303H | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E104K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E310Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L20L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L44L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | M311I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q489H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S230F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S337* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | T299A | Missense | 1 |
| BRCA | Breast invasive carcinoma | P89P | Silent | 1 |
| BRCA | Breast invasive carcinoma | S215S | Silent | 1 |
| BRCA | Breast invasive carcinoma | T64P | Missense | 1 |
| BRCA | Breast invasive carcinoma | V370V | Silent | 1 |
| CESC | Cervical and endocervical cancers | D26D | Silent | 1 |
| CESC | Cervical and endocervical cancers | F50L | Missense | 1 |
| COAD | Colon adenocarcinoma | E534D | Missense | 1 |
| COAD | Colon adenocarcinoma | F282V | Missense | 1 |
| COAD | Colon adenocarcinoma | G120C | Missense | 1 |
| COAD | Colon adenocarcinoma | G155S | Missense | 1 |
| COAD | Colon adenocarcinoma | G369G | Silent | 1 |
| COAD | Colon adenocarcinoma | G372G | Silent | 1 |
| COAD | Colon adenocarcinoma | H371H | Silent | 1 |
| COAD | Colon adenocarcinoma | T299T | Silent | 1 |
| COAD | Colon adenocarcinoma | V270A | Missense | 1 |
| COAD | Colon adenocarcinoma | V370M | Missense | 1 |
| COAD | Colon adenocarcinoma | V398I | Missense | 1 |
| ESCA | Esophageal carcinoma | A291T | Missense | 1 |
| ESCA | Esophageal carcinoma | L320P | Missense | 1 |
| ESCA | Esophageal carcinoma | R303C | Missense | 1 |
| GBM | Glioblastoma multiforme | R486S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A510V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E268Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Y294Y | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Y69F | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L20L | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | P194T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | Y473C | Missense | 1 |
| LUAD | Lung adenocarcinoma | A233A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A244D | Missense | 1 |
| LUAD | Lung adenocarcinoma | D327E | Missense | 1 |
| LUAD | Lung adenocarcinoma | E206Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | H332Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | L285F | Missense | 1 |
| LUAD | Lung adenocarcinoma | N392I | Missense | 1 |
| LUAD | Lung adenocarcinoma | N433S | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q113H | Missense | 1 |
| LUAD | Lung adenocarcinoma | R386L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S200S | Silent | 1 |
| LUAD | Lung adenocarcinoma | S256R | Missense | 1 |
| LUAD | Lung adenocarcinoma | T72K | Missense | 1 |
| LUAD | Lung adenocarcinoma | Y497N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A76A | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | P170H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | W376C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | V270V | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | A381T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A91V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | D335D | Silent | 1 |
| PRAD | Prostate adenocarcinoma | N341T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R56C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | Y391C | Missense | 1 |
| READ | Rectum adenocarcinoma | G373G | Silent | 1 |
| READ | Rectum adenocarcinoma | P241P | Silent | 1 |
| READ | Rectum adenocarcinoma | R303C | Missense | 1 |
| READ | Rectum adenocarcinoma | V270A | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A233A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A359A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A42A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A65T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E222K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E277K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F271F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G247E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G247R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G295E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H283Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I435I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L401L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L420F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L58L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P170P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P175L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P229P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P468S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q171* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | S216S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S218L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S292S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S301F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S428F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S51S | Silent | 1 |
| STAD | Stomach adenocarcinoma | A25A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A510V | Missense | 1 |
| STAD | Stomach adenocarcinoma | I487M | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q171H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S195L | Missense | 1 |
| STAD | Stomach adenocarcinoma | S195S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F350L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G295R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L320P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L345* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | M66V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R303H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R383C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T287M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 5.7 | 8.2 | 20 |
| BRCA | Breast invasive carcinoma | 976 | 8.6 | 1.4 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 2.9 | 1.4 | 0 |
| COAD | Colon adenocarcinoma | 367 | 11.4 | 9.6 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 4.1 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.4 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 2.9 | 4.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 2.9 | 1.4 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1.4 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 5.7 | 16.4 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 2.9 | 2.7 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2.9 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.7 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 2.9 | 4.1 | 0 |
| READ | Rectum adenocarcinoma | 122 | 5.7 | 2.7 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 40 | 20.5 | 60 |
| STAD | Stomach adenocarcinoma | 393 | 5.7 | 8.2 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 9.6 | 20 |