Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | D276H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | M127I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S386* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S63* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S82* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | G132G | Silent | 1 |
| BRCA | Breast invasive carcinoma | L203V | Missense | 1 |
| BRCA | Breast invasive carcinoma | S131R | Missense | 1 |
| BRCA | Breast invasive carcinoma | S517R | Missense | 1 |
| CESC | Cervical and endocervical cancers | T98P | Missense | 1 |
| COAD | Colon adenocarcinoma | F502S | Missense | 1 |
| COAD | Colon adenocarcinoma | G404C | Missense | 1 |
| COAD | Colon adenocarcinoma | I347I | Silent | 1 |
| COAD | Colon adenocarcinoma | L480P | Missense | 1 |
| ESCA | Esophageal carcinoma | A111T | Missense | 1 |
| ESCA | Esophageal carcinoma | A567D | Missense | 1 |
| ESCA | Esophageal carcinoma | R418S | Missense | 1 |
| ESCA | Esophageal carcinoma | T482S | Missense | 1 |
| GBM | Glioblastoma multiforme | T114T | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K13R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S256C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T136N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | I202V | Missense | 1 |
| LUAD | Lung adenocarcinoma | A246S | Missense | 1 |
| LUAD | Lung adenocarcinoma | E424K | Missense | 1 |
| LUAD | Lung adenocarcinoma | E4Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | P263S | Missense | 1 |
| LUAD | Lung adenocarcinoma | S256C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S472C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S82* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | K285N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S176C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L480V | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | T112N | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | D388V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | N65S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S138Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S255F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S563F | Missense | 1 |
| STAD | Stomach adenocarcinoma | A106T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A246V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A545V | Missense | 1 |
| STAD | Stomach adenocarcinoma | K430T | Missense | 1 |
| THCA | Thyroid carcinoma | L7* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E500* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F348L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G204D | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 5.3 | 50 |
| BRCA | Breast invasive carcinoma | 976 | 33.3 | 7.9 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.6 | 0 |
| COAD | Colon adenocarcinoma | 367 | 33.3 | 7.9 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 10.5 | 0 |
| GBM | Glioblastoma multiforme | 283 | 33.3 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 7.9 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2.6 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 15.8 | 16.7 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 5.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 5.3 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 2.6 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.6 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 0 | 7.9 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 10.5 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 16.7 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 5.3 | 16.7 |