Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | I336M | Missense | 2 |
| COAD | Colon adenocarcinoma | D301D | Silent | 2 |
| COAD | Colon adenocarcinoma | D301N | Missense | 2 |
| COAD | Colon adenocarcinoma | L152P | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | G291E | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | M412I | Missense | 2 |
| STAD | Stomach adenocarcinoma | A292V | Missense | 2 |
| STAD | Stomach adenocarcinoma | L152R | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L152I | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D34N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D375Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D418D | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L634L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L83P | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P271R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R345R | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S89S | Silent | 1 |
| BRCA | Breast invasive carcinoma | A110V | Missense | 1 |
| BRCA | Breast invasive carcinoma | A557A | Silent | 1 |
| BRCA | Breast invasive carcinoma | F326F | Silent | 1 |
| BRCA | Breast invasive carcinoma | L190F | Missense | 1 |
| BRCA | Breast invasive carcinoma | R342T | Missense | 1 |
| BRCA | Breast invasive carcinoma | S221N | Missense | 1 |
| CESC | Cervical and endocervical cancers | G113G | Silent | 1 |
| COAD | Colon adenocarcinoma | A110S | Missense | 1 |
| COAD | Colon adenocarcinoma | F226F | Silent | 1 |
| COAD | Colon adenocarcinoma | L117P | Missense | 1 |
| COAD | Colon adenocarcinoma | L465I | Missense | 1 |
| COAD | Colon adenocarcinoma | L521M | Missense | 1 |
| COAD | Colon adenocarcinoma | M240I | Missense | 1 |
| COAD | Colon adenocarcinoma | M616I | Missense | 1 |
| COAD | Colon adenocarcinoma | P102P | Silent | 1 |
| COAD | Colon adenocarcinoma | S264G | Missense | 1 |
| COAD | Colon adenocarcinoma | S296L | Missense | 1 |
| ESCA | Esophageal carcinoma | K581K | Silent | 1 |
| ESCA | Esophageal carcinoma | N8H | Missense | 1 |
| ESCA | Esophageal carcinoma | P617L | Missense | 1 |
| GBM | Glioblastoma multiforme | I570T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A529A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | C219F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D20Y | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G218G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K203K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P362P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q609K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S89T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T159T | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T179K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V75V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | A567V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V371V | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A633S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L628P | Missense | 1 |
| LAML | Acute Myeloid Leukemia | N321K | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T289T | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | L35L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | T47T | Silent | 1 |
| LUAD | Lung adenocarcinoma | A110D | Missense | 1 |
| LUAD | Lung adenocarcinoma | A162D | Missense | 1 |
| LUAD | Lung adenocarcinoma | A176A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A506A | Silent | 1 |
| LUAD | Lung adenocarcinoma | E378K | Missense | 1 |
| LUAD | Lung adenocarcinoma | G171W | Missense | 1 |
| LUAD | Lung adenocarcinoma | G470C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G520C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G566A | Missense | 1 |
| LUAD | Lung adenocarcinoma | L152H | Missense | 1 |
| LUAD | Lung adenocarcinoma | L628M | Missense | 1 |
| LUAD | Lung adenocarcinoma | M30V | Missense | 1 |
| LUAD | Lung adenocarcinoma | M401T | Missense | 1 |
| LUAD | Lung adenocarcinoma | M409K | Missense | 1 |
| LUAD | Lung adenocarcinoma | P241S | Missense | 1 |
| LUAD | Lung adenocarcinoma | P617H | Missense | 1 |
| LUAD | Lung adenocarcinoma | S351Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | T47T | Silent | 1 |
| LUAD | Lung adenocarcinoma | W619C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A180A | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | G207R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | N442D | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P271A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R408G | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S532C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S622F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V21V | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | A36G | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A510A | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | Y574C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A557V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | C219Y | Missense | 1 |
| READ | Rectum adenocarcinoma | E411* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | S272Y | Missense | 1 |
| READ | Rectum adenocarcinoma | T64N | Missense | 1 |
| SARC | Sarcoma | W374* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | D338N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D34N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D425N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D436N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E31K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E369K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E411K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E54K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G318E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G318R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G45D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G474E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G474G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G565E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G67E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I573F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I573L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K507E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L316L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P332S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P360L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q216Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Q5Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R587Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S170L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S213S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S24F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S288L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S51F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T261P | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T289M | Missense | 1 |
| STAD | Stomach adenocarcinoma | A162T | Missense | 1 |
| STAD | Stomach adenocarcinoma | C429W | Missense | 1 |
| STAD | Stomach adenocarcinoma | D114N | Missense | 1 |
| STAD | Stomach adenocarcinoma | F326F | Silent | 1 |
| STAD | Stomach adenocarcinoma | G218D | Missense | 1 |
| STAD | Stomach adenocarcinoma | I413S | Missense | 1 |
| STAD | Stomach adenocarcinoma | I570T | Missense | 1 |
| STAD | Stomach adenocarcinoma | K612E | Missense | 1 |
| STAD | Stomach adenocarcinoma | L152P | Missense | 1 |
| STAD | Stomach adenocarcinoma | P332P | Silent | 1 |
| STAD | Stomach adenocarcinoma | S296S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S540S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T111T | Silent | 1 |
| STAD | Stomach adenocarcinoma | T154I | Missense | 1 |
| STAD | Stomach adenocarcinoma | V177I | Missense | 1 |
| STAD | Stomach adenocarcinoma | V75F | Missense | 1 |
| STAD | Stomach adenocarcinoma | W619R | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y188* | Nonsense | 1 |
| TGCT | Testicular Germ Cell Tumors | G389W | Missense | 1 |
| THCA | Thyroid carcinoma | Q330K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A292A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A557V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C542* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D327N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E378* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E411* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G232G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L152V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L512P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P144H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P317S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P332P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S189I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S296L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y495C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 9.8 | 5 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 4.9 | 3.3 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 2.4 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 9.8 | 9.9 | 0 |
| ESCA | Esophageal carcinoma | 185 | 2.4 | 1.7 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0.8 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 14.6 | 4.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 2.4 | 0.8 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.7 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0.8 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 2.4 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 4.9 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 7.3 | 13.2 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 4.9 | 5 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0.8 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 2.4 | 0.8 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.7 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.7 | 16.7 |
| SARC | Sarcoma | 247 | 0 | 0 | 16.7 |
| SKCM | Skin Cutaneous Melanoma | 290 | 12.2 | 24.8 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 12.2 | 13.2 | 16.7 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0.8 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0.8 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 7.3 | 9.1 | 50 |