Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | P559S | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E325* | Nonsense | 2 |
| BLCA | Bladder urothelial carcinoma | E162Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E385Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G156G | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | G461G | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | K304K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | M253I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P90P | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q541H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R686* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | T335A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V139V | Silent | 1 |
| BRCA | Breast invasive carcinoma | P419P | Silent | 1 |
| BRCA | Breast invasive carcinoma | R27* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | R655P | Missense | 1 |
| BRCA | Breast invasive carcinoma | S691L | Missense | 1 |
| CESC | Cervical and endocervical cancers | E259Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | E58K | Missense | 1 |
| CESC | Cervical and endocervical cancers | K635K | Silent | 1 |
| CESC | Cervical and endocervical cancers | K635N | Missense | 1 |
| CESC | Cervical and endocervical cancers | M71I | Missense | 1 |
| COAD | Colon adenocarcinoma | E329K | Missense | 1 |
| COAD | Colon adenocarcinoma | E637K | Missense | 1 |
| COAD | Colon adenocarcinoma | E721E | Silent | 1 |
| COAD | Colon adenocarcinoma | E722G | Missense | 1 |
| COAD | Colon adenocarcinoma | I685N | Missense | 1 |
| COAD | Colon adenocarcinoma | K322N | Missense | 1 |
| COAD | Colon adenocarcinoma | K598N | Missense | 1 |
| COAD | Colon adenocarcinoma | L269L | Silent | 1 |
| COAD | Colon adenocarcinoma | R529H | Missense | 1 |
| COAD | Colon adenocarcinoma | W625C | Missense | 1 |
| ESCA | Esophageal carcinoma | D484N | Missense | 1 |
| ESCA | Esophageal carcinoma | L269L | Silent | 1 |
| ESCA | Esophageal carcinoma | R609H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | C605F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E721K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K384K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q66* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R258* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R301H | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | A415S | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G626G | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L459P | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | T335A | Missense | 1 |
| LGG | Brain Lower Grade Glioma | Q608H | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A239A | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | C299* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | E178Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E637G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L735F | Missense | 1 |
| LUAD | Lung adenocarcinoma | K201K | Silent | 1 |
| LUAD | Lung adenocarcinoma | K214N | Missense | 1 |
| LUAD | Lung adenocarcinoma | S640F | Missense | 1 |
| LUAD | Lung adenocarcinoma | T565A | Missense | 1 |
| LUAD | Lung adenocarcinoma | V622V | Silent | 1 |
| LUAD | Lung adenocarcinoma | V692L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | I478I | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | K546M | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q33K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S21Y | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | W595* | Nonsense | 1 |
| OV | Ovarian serous cystadenocarcinoma | E721K | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | E722V | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | K322R | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | Y575S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R362Q | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R301C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | T383A | Missense | 1 |
| READ | Rectum adenocarcinoma | R443* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | A577T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H313Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H366Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P133L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P133S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R443* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R557C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S405F | Missense | 1 |
| STAD | Stomach adenocarcinoma | A719V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D196N | Missense | 1 |
| STAD | Stomach adenocarcinoma | E246G | Missense | 1 |
| STAD | Stomach adenocarcinoma | E325K | Missense | 1 |
| STAD | Stomach adenocarcinoma | H446H | Silent | 1 |
| STAD | Stomach adenocarcinoma | Q66Q | Silent | 1 |
| STAD | Stomach adenocarcinoma | R655H | Missense | 1 |
| THCA | Thyroid carcinoma | M349L | Missense | 1 |
| THCA | Thyroid carcinoma | Y642F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E142D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E162* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G720G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I740I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L339I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P90P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R25Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R579* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R655H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R686Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y737Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 22.7 | 7.6 | 8.3 |
| BRCA | Breast invasive carcinoma | 976 | 4.5 | 3 | 8.3 |
| CESC | Cervical and endocervical cancers | 194 | 4.5 | 6.1 | 0 |
| COAD | Colon adenocarcinoma | 367 | 9.1 | 12.1 | 0 |
| ESCA | Esophageal carcinoma | 185 | 4.5 | 3 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 4.5 | 4.5 | 16.7 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 4.5 | 1.5 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 3 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1.5 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 4.5 | 4.5 | 8.3 |
| LUAD | Lung adenocarcinoma | 533 | 9.1 | 6.1 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 4.5 | 4.5 | 8.3 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 6.1 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.5 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 3 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 8.3 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 0 | 13.6 | 8.3 |
| STAD | Stomach adenocarcinoma | 393 | 9.1 | 7.6 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 3 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 18.2 | 7.6 | 33.3 |