Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | R442R | Silent | 3 |
| BLCA | Bladder urothelial carcinoma | L292L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R474* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | D530D | Silent | 1 |
| BRCA | Breast invasive carcinoma | E509K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E95K | Missense | 1 |
| BRCA | Breast invasive carcinoma | I59L | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q287E | Missense | 1 |
| BRCA | Breast invasive carcinoma | R484R | Silent | 1 |
| BRCA | Breast invasive carcinoma | R527H | Missense | 1 |
| BRCA | Breast invasive carcinoma | R564G | Missense | 1 |
| CESC | Cervical and endocervical cancers | E509K | Missense | 1 |
| CESC | Cervical and endocervical cancers | H556Y | Missense | 1 |
| CESC | Cervical and endocervical cancers | K119K | Silent | 1 |
| CESC | Cervical and endocervical cancers | L232V | Missense | 1 |
| CESC | Cervical and endocervical cancers | S178* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | A121V | Missense | 1 |
| COAD | Colon adenocarcinoma | A31T | Missense | 1 |
| COAD | Colon adenocarcinoma | E458E | Silent | 1 |
| COAD | Colon adenocarcinoma | E616D | Missense | 1 |
| COAD | Colon adenocarcinoma | G266E | Missense | 1 |
| COAD | Colon adenocarcinoma | M230L | Missense | 1 |
| COAD | Colon adenocarcinoma | R431H | Missense | 1 |
| COAD | Colon adenocarcinoma | R442* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R484C | Missense | 1 |
| COAD | Colon adenocarcinoma | R606C | Missense | 1 |
| COAD | Colon adenocarcinoma | R606H | Missense | 1 |
| ESCA | Esophageal carcinoma | P120H | Missense | 1 |
| ESCA | Esophageal carcinoma | T194S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L510F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R290S | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P618T | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | I173N | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | N240N | Silent | 1 |
| LGG | Brain Lower Grade Glioma | E221E | Silent | 1 |
| LGG | Brain Lower Grade Glioma | E280K | Missense | 1 |
| LGG | Brain Lower Grade Glioma | F126S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S514P | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G266R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | M187L | Missense | 1 |
| LUAD | Lung adenocarcinoma | A71A | Silent | 1 |
| LUAD | Lung adenocarcinoma | C141F | Missense | 1 |
| LUAD | Lung adenocarcinoma | D284N | Missense | 1 |
| LUAD | Lung adenocarcinoma | D464Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | E144* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E257V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G536R | Missense | 1 |
| LUAD | Lung adenocarcinoma | G536V | Missense | 1 |
| LUAD | Lung adenocarcinoma | H556L | Missense | 1 |
| LUAD | Lung adenocarcinoma | K148N | Missense | 1 |
| LUAD | Lung adenocarcinoma | P38T | Missense | 1 |
| LUAD | Lung adenocarcinoma | R111C | Missense | 1 |
| LUAD | Lung adenocarcinoma | R344G | Missense | 1 |
| LUAD | Lung adenocarcinoma | R484R | Silent | 1 |
| LUAD | Lung adenocarcinoma | R604L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S206C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P334S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R180L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R454P | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R483R | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | V621E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V67V | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | R442Q | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R606H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A516D | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R454H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R431H | Missense | 1 |
| READ | Rectum adenocarcinoma | D530D | Silent | 1 |
| READ | Rectum adenocarcinoma | I199V | Missense | 1 |
| READ | Rectum adenocarcinoma | R138Q | Missense | 1 |
| READ | Rectum adenocarcinoma | R484R | Silent | 1 |
| READ | Rectum adenocarcinoma | R527H | Missense | 1 |
| SARC | Sarcoma | E323K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E458K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S337S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S387F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S500F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V399V | Silent | 1 |
| STAD | Stomach adenocarcinoma | A205A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A98A | Silent | 1 |
| STAD | Stomach adenocarcinoma | D100D | Silent | 1 |
| STAD | Stomach adenocarcinoma | D438D | Silent | 1 |
| STAD | Stomach adenocarcinoma | E520K | Missense | 1 |
| STAD | Stomach adenocarcinoma | E75E | Silent | 1 |
| STAD | Stomach adenocarcinoma | E75Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | L196V | Missense | 1 |
| STAD | Stomach adenocarcinoma | P368P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P38A | Missense | 1 |
| STAD | Stomach adenocarcinoma | R226* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R562H | Missense | 1 |
| STAD | Stomach adenocarcinoma | T607T | Silent | 1 |
| THCA | Thyroid carcinoma | S514L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E280K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E319K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E321D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G231D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G482S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G529* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G538E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L279P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N422T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P475L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R113K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R431H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R532W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R558Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R611C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S277R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S577S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T261A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T607M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V250A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V628A | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 3.8 | 0 | 16.7 |
| BRCA | Breast invasive carcinoma | 976 | 7.7 | 7.2 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 3.8 | 3.6 | 16.7 |
| COAD | Colon adenocarcinoma | 367 | 15.4 | 10.8 | 16.7 |
| ESCA | Esophageal carcinoma | 185 | 0 | 2.4 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 2.4 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.2 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 3.8 | 1.2 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 3.8 | 3.6 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 2.4 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 7.7 | 15.7 | 16.7 |
| LUSC | Lung squamous cell carcinoma | 177 | 7.7 | 4.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.4 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 7.7 | 3.6 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.2 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 7.7 | 3.6 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 26.9 | 6 | 16.7 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.2 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 3.8 | 22.9 | 16.7 |