Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | D124H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E38K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I560I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | M503I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | N131S | Missense | 1 |
| BRCA | Breast invasive carcinoma | E476E | Silent | 1 |
| BRCA | Breast invasive carcinoma | K438N | Missense | 1 |
| CESC | Cervical and endocervical cancers | E476Q | Missense | 1 |
| COAD | Colon adenocarcinoma | G36G | Silent | 1 |
| COAD | Colon adenocarcinoma | M142L | Missense | 1 |
| COAD | Colon adenocarcinoma | P201Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R228W | Missense | 1 |
| COAD | Colon adenocarcinoma | R31* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R460W | Missense | 1 |
| COAD | Colon adenocarcinoma | T507T | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G437D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H378N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R228W | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P582S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P123A | Missense | 1 |
| LAML | Acute Myeloid Leukemia | R179* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | E387* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | I522M | Missense | 1 |
| LUAD | Lung adenocarcinoma | A251S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A295A | Silent | 1 |
| LUAD | Lung adenocarcinoma | E574* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | F379F | Silent | 1 |
| LUAD | Lung adenocarcinoma | M318I | Missense | 1 |
| LUAD | Lung adenocarcinoma | R228L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R414R | Silent | 1 |
| LUAD | Lung adenocarcinoma | R527L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S246I | Missense | 1 |
| LUAD | Lung adenocarcinoma | S70I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G565D | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R162L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D102G | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | M445I | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | E177A | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | G74G | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | P279L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R10R | Silent | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | I522V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A384A | Silent | 1 |
| PRAD | Prostate adenocarcinoma | Q237* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | E177K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G69V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H378Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R10C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R179Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R179R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R42C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S108C | Missense | 1 |
| STAD | Stomach adenocarcinoma | G69G | Silent | 1 |
| STAD | Stomach adenocarcinoma | L461L | Silent | 1 |
| STAD | Stomach adenocarcinoma | S17C | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | T507T | Silent | 1 |
| THCA | Thyroid carcinoma | P537L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A315V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L485I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R264H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R414Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R573C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S586L | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 7.1 | 9.1 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 7.1 | 2.3 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.3 | 0 |
| COAD | Colon adenocarcinoma | 367 | 14.3 | 9.1 | 20 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 6.8 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.3 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.3 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 20 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 2.3 | 20 |
| LUAD | Lung adenocarcinoma | 533 | 21.4 | 13.6 | 20 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.5 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 4.5 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 14.3 | 4.5 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 2.3 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 7.1 | 0 | 20 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 7.1 | 15.9 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 14.3 | 2.3 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 7.1 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 2.3 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 13.6 | 0 |