Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | R76C | Missense | 5 |
| SKCM | Skin Cutaneous Melanoma | I94I | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | D66Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E214K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E93D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R100I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R239L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S226F | Missense | 1 |
| BRCA | Breast invasive carcinoma | G111G | Silent | 1 |
| CESC | Cervical and endocervical cancers | S179F | Missense | 1 |
| COAD | Colon adenocarcinoma | E136K | Missense | 1 |
| COAD | Colon adenocarcinoma | I94I | Silent | 1 |
| COAD | Colon adenocarcinoma | Q297H | Missense | 1 |
| GBM | Glioblastoma multiforme | M223I | Missense | 1 |
| GBM | Glioblastoma multiforme | P301S | Missense | 1 |
| GBM | Glioblastoma multiforme | Y71* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G242C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P301A | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P50T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R239* | Nonsense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | E288G | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Y71H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R188Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | D69N | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | F302L | Missense | 1 |
| LUAD | Lung adenocarcinoma | A208S | Missense | 1 |
| LUAD | Lung adenocarcinoma | E236* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | H290Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | M210I | Missense | 1 |
| LUAD | Lung adenocarcinoma | M223I | Missense | 1 |
| LUAD | Lung adenocarcinoma | R188Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | T135T | Silent | 1 |
| LUAD | Lung adenocarcinoma | V266V | Silent | 1 |
| LUAD | Lung adenocarcinoma | Y295Y | Silent | 1 |
| LUAD | Lung adenocarcinoma | Y32H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P158T | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P261S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R274S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S122* | Nonsense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D175Y | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R274H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | V216D | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | V95I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | T135T | Silent | 1 |
| READ | Rectum adenocarcinoma | I264I | Silent | 1 |
| READ | Rectum adenocarcinoma | N91D | Missense | 1 |
| SARC | Sarcoma | V116L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E228K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E269D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E288K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G113G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G150E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G189G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H157Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H33D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K98E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L174L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L299L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L89L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | M252I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R100K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R246Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R250Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S273S | Silent | 1 |
| STAD | Stomach adenocarcinoma | C287Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | C294Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | E108* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | N73N | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F78L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P261Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R250Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R274C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R275I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S128S | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 10.5 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 5.9 | 0 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.8 | 0 |
| COAD | Colon adenocarcinoma | 367 | 5.9 | 3.5 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 3.5 | 20 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 5.3 | 20 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 3.5 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1.8 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 3.5 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 17.6 | 10.5 | 20 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 5.3 | 20 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.8 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 3.5 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 1.8 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 5.9 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 5.9 | 1.8 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.8 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 47.1 | 28.1 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 5.9 | 3.5 | 20 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 5.9 | 8.8 | 0 |