Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | I282I | Silent | 2 |
| STAD | Stomach adenocarcinoma | A419V | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A199V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E125E | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | E153K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E226K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G271A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q391* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S248F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T99T | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | W202* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | E153D | Missense | 1 |
| BRCA | Breast invasive carcinoma | E153K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E208K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E453K | Missense | 1 |
| BRCA | Breast invasive carcinoma | I282I | Silent | 1 |
| BRCA | Breast invasive carcinoma | P520L | Missense | 1 |
| CESC | Cervical and endocervical cancers | F498L | Missense | 1 |
| CESC | Cervical and endocervical cancers | S151C | Missense | 1 |
| CESC | Cervical and endocervical cancers | V517G | Missense | 1 |
| COAD | Colon adenocarcinoma | A419V | Missense | 1 |
| COAD | Colon adenocarcinoma | C330C | Silent | 1 |
| COAD | Colon adenocarcinoma | D396D | Silent | 1 |
| COAD | Colon adenocarcinoma | G492* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R171G | Missense | 1 |
| COAD | Colon adenocarcinoma | V547M | Missense | 1 |
| ESCA | Esophageal carcinoma | R352H | Missense | 1 |
| GBM | Glioblastoma multiforme | G343S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A194A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A510A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E178K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G281R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R508S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V368I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V547V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | H553Q | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A311G | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | G38R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | K61K | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | I451V | Missense | 1 |
| LUAD | Lung adenocarcinoma | M70I | Missense | 1 |
| LUAD | Lung adenocarcinoma | R169R | Silent | 1 |
| LUAD | Lung adenocarcinoma | R378W | Missense | 1 |
| LUAD | Lung adenocarcinoma | R508H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A53V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D51Y | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | I351I | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | T236T | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | V136L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P184L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R171W | Missense | 1 |
| PRAD | Prostate adenocarcinoma | T205A | Missense | 1 |
| SARC | Sarcoma | V517I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D212N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G195R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H219Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I471I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P174L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P386L | Missense | 1 |
| STAD | Stomach adenocarcinoma | A206T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A229D | Missense | 1 |
| STAD | Stomach adenocarcinoma | F417S | Missense | 1 |
| STAD | Stomach adenocarcinoma | F425S | Missense | 1 |
| STAD | Stomach adenocarcinoma | K35R | Missense | 1 |
| STAD | Stomach adenocarcinoma | M523V | Missense | 1 |
| STAD | Stomach adenocarcinoma | R169W | Missense | 1 |
| STAD | Stomach adenocarcinoma | S158Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | T246N | Missense | 1 |
| STAD | Stomach adenocarcinoma | V517I | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | D538E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A536V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G397R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K338N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N542N | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T294A | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 12.5 | 8.6 | 66.7 |
| BRCA | Breast invasive carcinoma | 976 | 6.2 | 8.6 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 5.2 | 0 |
| COAD | Colon adenocarcinoma | 367 | 12.5 | 5.2 | 33.3 |
| ESCA | Esophageal carcinoma | 185 | 0 | 1.7 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.7 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 18.8 | 6.9 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.7 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 3.4 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 6.2 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 1.7 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 6.2 | 5.2 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 12.5 | 3.4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.7 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 5.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.7 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 18.8 | 8.6 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 20.7 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.7 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 6.2 | 6.9 | 0 |