Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | Y380Y | Silent | 2 |
| STAD | Stomach adenocarcinoma | L233L | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | A135T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E210Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E694K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F573C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H414R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L185L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L411L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L450L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | N346D | Missense | 1 |
| BRCA | Breast invasive carcinoma | A595V | Missense | 1 |
| BRCA | Breast invasive carcinoma | D538N | Missense | 1 |
| BRCA | Breast invasive carcinoma | E128Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q260R | Missense | 1 |
| CESC | Cervical and endocervical cancers | D175N | Missense | 1 |
| CESC | Cervical and endocervical cancers | F317F | Silent | 1 |
| CESC | Cervical and endocervical cancers | I86I | Silent | 1 |
| COAD | Colon adenocarcinoma | E520E | Silent | 1 |
| COAD | Colon adenocarcinoma | F133F | Silent | 1 |
| COAD | Colon adenocarcinoma | G660G | Silent | 1 |
| COAD | Colon adenocarcinoma | R710H | Missense | 1 |
| ESCA | Esophageal carcinoma | R326* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | R710R | Silent | 1 |
| GBM | Glioblastoma multiforme | R54W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | C174C | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G272V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G486C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N412I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P229P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P69P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q434H | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E720E | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | V80L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | G42R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P41P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | K564N | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N198S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S793G | Missense | 1 |
| LUAD | Lung adenocarcinoma | E624Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | L712L | Silent | 1 |
| LUAD | Lung adenocarcinoma | P293L | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q143P | Missense | 1 |
| LUAD | Lung adenocarcinoma | R326Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | T591T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | G338V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q509H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S273S | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | E667K | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | Y380C | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | Q589* | Nonsense | 1 |
| PRAD | Prostate adenocarcinoma | C174C | Silent | 1 |
| PRAD | Prostate adenocarcinoma | G420G | Silent | 1 |
| READ | Rectum adenocarcinoma | F133F | Silent | 1 |
| READ | Rectum adenocarcinoma | R759H | Missense | 1 |
| READ | Rectum adenocarcinoma | Y380Y | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F145F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H414Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P159L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P339L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P484L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R759C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S302L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S389S | Silent | 1 |
| STAD | Stomach adenocarcinoma | A135V | Missense | 1 |
| STAD | Stomach adenocarcinoma | C174Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | F133F | Silent | 1 |
| STAD | Stomach adenocarcinoma | G334V | Missense | 1 |
| STAD | Stomach adenocarcinoma | I193T | Missense | 1 |
| STAD | Stomach adenocarcinoma | P159S | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q511Q | Silent | 1 |
| STAD | Stomach adenocarcinoma | R241W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R725I | Missense | 1 |
| STAD | Stomach adenocarcinoma | V287M | Missense | 1 |
| STAD | Stomach adenocarcinoma | W72* | Nonsense | 1 |
| TGCT | Testicular Germ Cell Tumors | R190L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A134T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A431T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C174C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F164I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I676I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L233I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L539* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S407F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S627Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S819Y | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 9.7 | 11.3 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 7.5 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 6.5 | 1.9 | 0 |
| COAD | Colon adenocarcinoma | 367 | 16.1 | 1.9 | 0 |
| ESCA | Esophageal carcinoma | 185 | 3.2 | 0 | 25 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.9 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 9.7 | 7.5 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 3.2 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.9 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 3.2 | 1.9 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 5.7 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 6.5 | 7.5 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 3.2 | 3.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 3.8 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 25 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 6.5 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 6.5 | 1.9 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 6.5 | 11.3 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 12.9 | 15.1 | 25 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.9 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 6.5 | 13.2 | 25 |