Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | T458A | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E92Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G71V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H276Y | Missense | 1 |
| BRCA | Breast invasive carcinoma | D151H | Missense | 1 |
| BRCA | Breast invasive carcinoma | E43Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | G662R | Missense | 1 |
| BRCA | Breast invasive carcinoma | G89E | Missense | 1 |
| BRCA | Breast invasive carcinoma | R107H | Missense | 1 |
| BRCA | Breast invasive carcinoma | S401* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | S467T | Missense | 1 |
| BRCA | Breast invasive carcinoma | V64L | Missense | 1 |
| CESC | Cervical and endocervical cancers | E102K | Missense | 1 |
| CESC | Cervical and endocervical cancers | G317G | Silent | 1 |
| CESC | Cervical and endocervical cancers | I45I | Silent | 1 |
| CESC | Cervical and endocervical cancers | L390F | Missense | 1 |
| CESC | Cervical and endocervical cancers | R245* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | A22T | Missense | 1 |
| COAD | Colon adenocarcinoma | A593V | Missense | 1 |
| COAD | Colon adenocarcinoma | G136G | Silent | 1 |
| COAD | Colon adenocarcinoma | G239W | Missense | 1 |
| COAD | Colon adenocarcinoma | K308K | Silent | 1 |
| COAD | Colon adenocarcinoma | K639T | Missense | 1 |
| COAD | Colon adenocarcinoma | K768N | Missense | 1 |
| COAD | Colon adenocarcinoma | Q783R | Missense | 1 |
| COAD | Colon adenocarcinoma | R326Q | Missense | 1 |
| COAD | Colon adenocarcinoma | S246N | Missense | 1 |
| COAD | Colon adenocarcinoma | T458M | Missense | 1 |
| COAD | Colon adenocarcinoma | T458T | Silent | 1 |
| COAD | Colon adenocarcinoma | T56M | Missense | 1 |
| COAD | Colon adenocarcinoma | T56T | Silent | 1 |
| ESCA | Esophageal carcinoma | E582D | Missense | 1 |
| ESCA | Esophageal carcinoma | G420C | Missense | 1 |
| ESCA | Esophageal carcinoma | K592* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | P681H | Missense | 1 |
| ESCA | Esophageal carcinoma | R245Q | Missense | 1 |
| ESCA | Esophageal carcinoma | S5S | Silent | 1 |
| GBM | Glioblastoma multiforme | Y135Y | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L610F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S625* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T739I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V113V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | D151A | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P578P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | A630A | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | D334D | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | P123P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | T369A | Missense | 1 |
| LUAD | Lung adenocarcinoma | D415N | Missense | 1 |
| LUAD | Lung adenocarcinoma | E167* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E691K | Missense | 1 |
| LUAD | Lung adenocarcinoma | F142C | Missense | 1 |
| LUAD | Lung adenocarcinoma | I624F | Missense | 1 |
| LUAD | Lung adenocarcinoma | L145P | Missense | 1 |
| LUAD | Lung adenocarcinoma | N786S | Missense | 1 |
| LUAD | Lung adenocarcinoma | P703L | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q389K | Missense | 1 |
| LUAD | Lung adenocarcinoma | R27P | Missense | 1 |
| LUAD | Lung adenocarcinoma | W9* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | E445* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | K485R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L502R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | N724I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S303Y | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | W330C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S203S | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | T458M | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | K138N | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A472A | Silent | 1 |
| PRAD | Prostate adenocarcinoma | H475Y | Missense | 1 |
| PRAD | Prostate adenocarcinoma | L291L | Silent | 1 |
| PRAD | Prostate adenocarcinoma | M230I | Missense | 1 |
| READ | Rectum adenocarcinoma | E150K | Missense | 1 |
| READ | Rectum adenocarcinoma | R780W | Missense | 1 |
| READ | Rectum adenocarcinoma | T458T | Silent | 1 |
| SARC | Sarcoma | P675S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G129* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | P466S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P584L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R127R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R780W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S274L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S285L | Missense | 1 |
| STAD | Stomach adenocarcinoma | E582K | Missense | 1 |
| STAD | Stomach adenocarcinoma | G324S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R218H | Missense | 1 |
| STAD | Stomach adenocarcinoma | T458T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A28S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E191G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E558* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L468L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L643I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P187H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R127Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R596* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S131I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V86L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V91A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | W232C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y710Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 4.3 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 10 | 10 |
| CESC | Cervical and endocervical cancers | 194 | 9.5 | 2.9 | 10 |
| COAD | Colon adenocarcinoma | 367 | 19 | 17.1 | 0 |
| ESCA | Esophageal carcinoma | 185 | 4.8 | 5.7 | 10 |
| GBM | Glioblastoma multiforme | 283 | 4.8 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 4.8 | 2.9 | 10 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.4 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 4.8 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 14.3 | 1.4 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 12.9 | 20 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 7.1 | 10 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 4.8 | 1.4 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 9.5 | 2.9 | 0 |
| READ | Rectum adenocarcinoma | 122 | 4.8 | 2.9 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.4 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 4.8 | 7.1 | 10 |
| STAD | Stomach adenocarcinoma | 393 | 4.8 | 4.3 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.5 | 12.9 | 20 |