Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | A434V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | C102C | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L182L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L381L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R411H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S545C | Missense | 1 |
| BRCA | Breast invasive carcinoma | L585V | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q112Q | Silent | 1 |
| CESC | Cervical and endocervical cancers | V424V | Silent | 1 |
| COAD | Colon adenocarcinoma | A488A | Silent | 1 |
| ESCA | Esophageal carcinoma | A487V | Missense | 1 |
| ESCA | Esophageal carcinoma | L499M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A415T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E454E | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E54K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R651T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | W194* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | A480V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | A487V | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L560L | Silent | 1 |
| LGG | Brain Lower Grade Glioma | A85V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | L16M | Missense | 1 |
| LUAD | Lung adenocarcinoma | E24Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | E54Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | F542L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | G553S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A390T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A392T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | C315Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E439E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E439K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E442K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E454E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E454K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G376G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | M316I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P665S | Missense | 1 |
| STAD | Stomach adenocarcinoma | A364T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A392S | Missense | 1 |
| STAD | Stomach adenocarcinoma | L650M | Missense | 1 |
| STAD | Stomach adenocarcinoma | P352Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R347C | Missense | 1 |
| THCA | Thyroid carcinoma | P325P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R377R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V509M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 23.1 | 9.7 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 7.7 | 3.2 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 7.7 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 7.7 | 0 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 6.5 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 7.7 | 9.7 | 100 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 6.5 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 7.7 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 6.5 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 6.5 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 3.2 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 3.2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 23.1 | 25.8 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 16.1 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 7.7 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 7.7 | 3.2 | 0 |