Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| ESCA | Esophageal carcinoma | F746L | Missense | 6 |
| COAD | Colon adenocarcinoma | R702R | Silent | 3 |
| BLCA | Bladder urothelial carcinoma | A312A | Silent | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1015C | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S348L | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D54N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E587Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S219S | Silent | 1 |
| BRCA | Breast invasive carcinoma | F746L | Missense | 1 |
| BRCA | Breast invasive carcinoma | G623C | Missense | 1 |
| BRCA | Breast invasive carcinoma | G769E | Missense | 1 |
| BRCA | Breast invasive carcinoma | L1062L | Silent | 1 |
| BRCA | Breast invasive carcinoma | L256L | Silent | 1 |
| BRCA | Breast invasive carcinoma | L378V | Missense | 1 |
| BRCA | Breast invasive carcinoma | T327T | Silent | 1 |
| CESC | Cervical and endocervical cancers | F746L | Missense | 1 |
| CESC | Cervical and endocervical cancers | P884P | Silent | 1 |
| CESC | Cervical and endocervical cancers | R138C | Missense | 1 |
| COAD | Colon adenocarcinoma | A235A | Silent | 1 |
| COAD | Colon adenocarcinoma | A295T | Missense | 1 |
| COAD | Colon adenocarcinoma | A325A | Silent | 1 |
| COAD | Colon adenocarcinoma | A552T | Missense | 1 |
| COAD | Colon adenocarcinoma | D273G | Missense | 1 |
| COAD | Colon adenocarcinoma | G623D | Missense | 1 |
| COAD | Colon adenocarcinoma | H104H | Silent | 1 |
| COAD | Colon adenocarcinoma | H331R | Missense | 1 |
| COAD | Colon adenocarcinoma | K172N | Missense | 1 |
| COAD | Colon adenocarcinoma | P300S | Missense | 1 |
| COAD | Colon adenocarcinoma | P727H | Missense | 1 |
| COAD | Colon adenocarcinoma | Q103* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | Q116R | Missense | 1 |
| COAD | Colon adenocarcinoma | Q712* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R52H | Missense | 1 |
| COAD | Colon adenocarcinoma | S197N | Missense | 1 |
| COAD | Colon adenocarcinoma | S930T | Missense | 1 |
| COAD | Colon adenocarcinoma | V641M | Missense | 1 |
| ESCA | Esophageal carcinoma | A909V | Missense | 1 |
| ESCA | Esophageal carcinoma | G896C | Missense | 1 |
| ESCA | Esophageal carcinoma | P578L | Missense | 1 |
| ESCA | Esophageal carcinoma | R1029P | Missense | 1 |
| ESCA | Esophageal carcinoma | R530C | Missense | 1 |
| ESCA | Esophageal carcinoma | S197S | Silent | 1 |
| GBM | Glioblastoma multiforme | A312V | Missense | 1 |
| GBM | Glioblastoma multiforme | L908L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A1060S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D198N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D878Y | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E986* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I88N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P518L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1015C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1061L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S298S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T692T | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q85E | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | T787T | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | I981I | Silent | 1 |
| LGG | Brain Lower Grade Glioma | C698C | Silent | 1 |
| LGG | Brain Lower Grade Glioma | E1049K | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P1009P | Silent | 1 |
| LGG | Brain Lower Grade Glioma | R52H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S306N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S817S | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | D659G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L108P | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L385F | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S2G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S350S | Silent | 1 |
| LUAD | Lung adenocarcinoma | A1058A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A185S | Missense | 1 |
| LUAD | Lung adenocarcinoma | D537V | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1002D | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1076D | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1080* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E973K | Missense | 1 |
| LUAD | Lung adenocarcinoma | G769V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G801V | Missense | 1 |
| LUAD | Lung adenocarcinoma | L280L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L59L | Silent | 1 |
| LUAD | Lung adenocarcinoma | N181N | Silent | 1 |
| LUAD | Lung adenocarcinoma | P284S | Missense | 1 |
| LUAD | Lung adenocarcinoma | P352L | Missense | 1 |
| LUAD | Lung adenocarcinoma | P60A | Missense | 1 |
| LUAD | Lung adenocarcinoma | P917P | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q547H | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q557H | Missense | 1 |
| LUAD | Lung adenocarcinoma | R148G | Missense | 1 |
| LUAD | Lung adenocarcinoma | R516R | Silent | 1 |
| LUAD | Lung adenocarcinoma | R543Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | S168I | Missense | 1 |
| LUAD | Lung adenocarcinoma | V1004I | Missense | 1 |
| LUAD | Lung adenocarcinoma | V277V | Silent | 1 |
| LUAD | Lung adenocarcinoma | V556L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L241F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L413V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L972L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | Q107K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R681K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S741S | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | T1055T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | V927V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | Y946C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | H193P | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R702R | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | Q644* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | R448W | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S348S | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | S684G | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | C982C | Silent | 1 |
| PRAD | Prostate adenocarcinoma | A35T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A795D | Missense | 1 |
| PRAD | Prostate adenocarcinoma | Y852C | Missense | 1 |
| READ | Rectum adenocarcinoma | R702R | Silent | 1 |
| READ | Rectum adenocarcinoma | S294S | Silent | 1 |
| READ | Rectum adenocarcinoma | T725T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D198N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F933F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L656F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | N729Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P424L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P545S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P572P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P618P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P924S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P942L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1016S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S348L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S741L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T648T | Silent | 1 |
| STAD | Stomach adenocarcinoma | A1045T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A373T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A37V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A440T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A552T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A909V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D234N | Missense | 1 |
| STAD | Stomach adenocarcinoma | D977N | Missense | 1 |
| STAD | Stomach adenocarcinoma | E1070K | Missense | 1 |
| STAD | Stomach adenocarcinoma | E585* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | G299R | Missense | 1 |
| STAD | Stomach adenocarcinoma | L663V | Missense | 1 |
| STAD | Stomach adenocarcinoma | P228L | Missense | 1 |
| STAD | Stomach adenocarcinoma | P423P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P618P | Silent | 1 |
| STAD | Stomach adenocarcinoma | Q1006R | Missense | 1 |
| STAD | Stomach adenocarcinoma | R200C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R601Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S741P | Missense | 1 |
| STAD | Stomach adenocarcinoma | T355M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V857V | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | R67W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A185V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A768V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A774V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F871F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K958N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | M504I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P284L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P884P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R255R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R283C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S168N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S219S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S817S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S817Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V310I | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 5.7 | 1.7 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 5.7 | 3.4 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 1.9 | 1.7 | 0 |
| COAD | Colon adenocarcinoma | 367 | 11.3 | 11.1 | 33.3 |
| ESCA | Esophageal carcinoma | 185 | 1.9 | 9.4 | 0 |
| GBM | Glioblastoma multiforme | 283 | 1.9 | 0.9 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.8 | 6 | 16.7 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 1.9 | 0.9 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 1.9 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 5.7 | 2.6 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 1.9 | 3.4 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 13.2 | 14.5 | 16.7 |
| LUSC | Lung squamous cell carcinoma | 177 | 7.5 | 4.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 1.9 | 0.9 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 1.9 | 1.7 | 16.7 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 1.9 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.6 | 0 |
| READ | Rectum adenocarcinoma | 122 | 5.7 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 9.4 | 7.7 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 5.7 | 14.5 | 16.7 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0.9 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.4 | 12 | 0 |