Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | Q583R | Missense | 4 |
| BLCA | Bladder urothelial carcinoma | E591Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E614K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E620K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I1011I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q468* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q88L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S886C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T412T | Silent | 1 |
| BRCA | Breast invasive carcinoma | E156E | Silent | 1 |
| BRCA | Breast invasive carcinoma | E161K | Missense | 1 |
| BRCA | Breast invasive carcinoma | G567E | Missense | 1 |
| BRCA | Breast invasive carcinoma | P208S | Missense | 1 |
| BRCA | Breast invasive carcinoma | S422F | Missense | 1 |
| BRCA | Breast invasive carcinoma | W792* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | F95S | Missense | 1 |
| CESC | Cervical and endocervical cancers | K853E | Missense | 1 |
| COAD | Colon adenocarcinoma | A1043T | Missense | 1 |
| COAD | Colon adenocarcinoma | A613V | Missense | 1 |
| COAD | Colon adenocarcinoma | A624D | Missense | 1 |
| COAD | Colon adenocarcinoma | E574D | Missense | 1 |
| COAD | Colon adenocarcinoma | K693K | Silent | 1 |
| COAD | Colon adenocarcinoma | L124L | Silent | 1 |
| COAD | Colon adenocarcinoma | L865P | Missense | 1 |
| COAD | Colon adenocarcinoma | N921N | Silent | 1 |
| COAD | Colon adenocarcinoma | Q583H | Missense | 1 |
| COAD | Colon adenocarcinoma | S308L | Missense | 1 |
| COAD | Colon adenocarcinoma | S308S | Silent | 1 |
| COAD | Colon adenocarcinoma | V1044V | Silent | 1 |
| ESCA | Esophageal carcinoma | T234M | Missense | 1 |
| ESCA | Esophageal carcinoma | V848V | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A1065A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A1090V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E908K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I290I | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q146* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q453Q | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A849G | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | D896Y | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R60W | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P391P | Silent | 1 |
| LGG | Brain Lower Grade Glioma | R284C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T412T | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | D964H | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L450L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | Q74K | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R60W | Missense | 1 |
| LUAD | Lung adenocarcinoma | H441L | Missense | 1 |
| LUAD | Lung adenocarcinoma | L282L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L346L | Silent | 1 |
| LUAD | Lung adenocarcinoma | P1115R | Missense | 1 |
| LUAD | Lung adenocarcinoma | R894H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | T721A | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L17L | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | Q583E | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A839S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | P770L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S960S | Silent | 1 |
| PRAD | Prostate adenocarcinoma | G304W | Missense | 1 |
| PRAD | Prostate adenocarcinoma | H109Y | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R455Q | Missense | 1 |
| READ | Rectum adenocarcinoma | A1043T | Missense | 1 |
| READ | Rectum adenocarcinoma | V380V | Silent | 1 |
| SARC | Sarcoma | Q878E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D763H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E1003K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E1106K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E18Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F1064F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L17L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L993L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1120L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P232L | Missense | 1 |
| STAD | Stomach adenocarcinoma | C1060Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | C698C | Silent | 1 |
| STAD | Stomach adenocarcinoma | D870D | Silent | 1 |
| STAD | Stomach adenocarcinoma | E550D | Missense | 1 |
| STAD | Stomach adenocarcinoma | I300T | Missense | 1 |
| STAD | Stomach adenocarcinoma | I730N | Missense | 1 |
| STAD | Stomach adenocarcinoma | K726T | Missense | 1 |
| STAD | Stomach adenocarcinoma | P770H | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q99H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R72W | Missense | 1 |
| STAD | Stomach adenocarcinoma | T473M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V430M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V801M | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | C807C | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | L1092M | Missense | 1 |
| THCA | Thyroid carcinoma | P322A | Missense | 1 |
| THCA | Thyroid carcinoma | S225S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1010T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A777V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A834V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A880V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1052K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E140E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G202S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I714I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I932I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K196N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R482W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R60W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R710Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S309S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S394L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V562V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 6.2 | 6.8 | 33.3 |
| BRCA | Breast invasive carcinoma | 976 | 3.1 | 5.4 | 33.3 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.7 | 0 |
| COAD | Colon adenocarcinoma | 367 | 15.6 | 14.9 | 0 |
| ESCA | Esophageal carcinoma | 185 | 3.1 | 1.4 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 9.4 | 2.7 | 33.3 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 4.1 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 6.2 | 1.4 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.1 | 4.1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 6.2 | 4.1 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 1.4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 3.1 | 1.4 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 3.1 | 2.7 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 4.1 | 0 |
| READ | Rectum adenocarcinoma | 122 | 3.1 | 1.4 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.4 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 9.4 | 8.1 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 6.2 | 14.9 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 3.1 | 1.4 | 0 |
| THCA | Thyroid carcinoma | 495 | 3.1 | 1.4 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 15.6 | 14.9 | 0 |