Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BRCA | Breast invasive carcinoma | H286P | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D1128H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E333Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E432Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E562D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G1014W | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G344E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H1115R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L749L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R236L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R480C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T260A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V874F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | W705* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | A1106A | Silent | 1 |
| BRCA | Breast invasive carcinoma | A184A | Silent | 1 |
| BRCA | Breast invasive carcinoma | A602A | Silent | 1 |
| BRCA | Breast invasive carcinoma | D567Y | Missense | 1 |
| BRCA | Breast invasive carcinoma | E1061K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E840Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | G70R | Missense | 1 |
| BRCA | Breast invasive carcinoma | H764P | Missense | 1 |
| BRCA | Breast invasive carcinoma | I1157V | Missense | 1 |
| BRCA | Breast invasive carcinoma | M867I | Missense | 1 |
| BRCA | Breast invasive carcinoma | P285P | Silent | 1 |
| BRCA | Breast invasive carcinoma | Q909L | Missense | 1 |
| BRCA | Breast invasive carcinoma | R282S | Missense | 1 |
| BRCA | Breast invasive carcinoma | R870Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | S846T | Missense | 1 |
| CESC | Cervical and endocervical cancers | I507M | Missense | 1 |
| CESC | Cervical and endocervical cancers | L112I | Missense | 1 |
| CESC | Cervical and endocervical cancers | R673C | Missense | 1 |
| CESC | Cervical and endocervical cancers | S995L | Missense | 1 |
| COAD | Colon adenocarcinoma | A331T | Missense | 1 |
| COAD | Colon adenocarcinoma | C99C | Silent | 1 |
| COAD | Colon adenocarcinoma | G1014R | Missense | 1 |
| COAD | Colon adenocarcinoma | G758G | Silent | 1 |
| COAD | Colon adenocarcinoma | G758V | Missense | 1 |
| COAD | Colon adenocarcinoma | P748P | Silent | 1 |
| COAD | Colon adenocarcinoma | R1155C | Missense | 1 |
| COAD | Colon adenocarcinoma | R315W | Missense | 1 |
| COAD | Colon adenocarcinoma | R588H | Missense | 1 |
| COAD | Colon adenocarcinoma | S458S | Silent | 1 |
| ESCA | Esophageal carcinoma | G935V | Missense | 1 |
| ESCA | Esophageal carcinoma | R134Q | Missense | 1 |
| ESCA | Esophageal carcinoma | R721H | Missense | 1 |
| GBM | Glioblastoma multiforme | G60S | Missense | 1 |
| GBM | Glioblastoma multiforme | P803P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | C426F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D1210V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D963H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E92K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G1169G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G300G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G746W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M207L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R842I | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G518G | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | G977D | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | I507V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | I510T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | K854K | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | D714G | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | E49G | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R1096R | Silent | 1 |
| LGG | Brain Lower Grade Glioma | E110K | Missense | 1 |
| LGG | Brain Lower Grade Glioma | G1126C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | N1142D | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A321S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E279G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | F131L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K36R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R606R | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | R773L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S28S | Silent | 1 |
| LUAD | Lung adenocarcinoma | C1133* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | G189G | Silent | 1 |
| LUAD | Lung adenocarcinoma | H255N | Missense | 1 |
| LUAD | Lung adenocarcinoma | M767I | Missense | 1 |
| LUAD | Lung adenocarcinoma | P106P | Silent | 1 |
| LUAD | Lung adenocarcinoma | P106R | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1212P | Silent | 1 |
| LUAD | Lung adenocarcinoma | P408H | Missense | 1 |
| LUAD | Lung adenocarcinoma | P45R | Missense | 1 |
| LUAD | Lung adenocarcinoma | T869S | Missense | 1 |
| LUAD | Lung adenocarcinoma | V89L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | G1082R | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | G758S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L508L | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | P748T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L537F | Missense | 1 |
| PRAD | Prostate adenocarcinoma | D567H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | F566L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | H368Y | Missense | 1 |
| READ | Rectum adenocarcinoma | G692G | Silent | 1 |
| READ | Rectum adenocarcinoma | P45H | Missense | 1 |
| READ | Rectum adenocarcinoma | Q1043H | Missense | 1 |
| SARC | Sarcoma | G1169V | Missense | 1 |
| SARC | Sarcoma | P748L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F576F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H492H | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I820I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L192F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L962L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P213T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P803P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Q950Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R127C | Missense | 1 |
| STAD | Stomach adenocarcinoma | A374A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A82A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A988T | Missense | 1 |
| STAD | Stomach adenocarcinoma | H500R | Missense | 1 |
| STAD | Stomach adenocarcinoma | L765M | Missense | 1 |
| STAD | Stomach adenocarcinoma | M511V | Missense | 1 |
| STAD | Stomach adenocarcinoma | P360L | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q261* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R835Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S755L | Missense | 1 |
| STAD | Stomach adenocarcinoma | T263T | Silent | 1 |
| STAD | Stomach adenocarcinoma | V395I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1181V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A358T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A374V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C572C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1017K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1061K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E871* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F297F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F576F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F623L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G300D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G394G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G584D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G844G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K553Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | M159I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P1171L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P285T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P433L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P708S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R14Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R33Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R561H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R709H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R721H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R828H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S398S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S790S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V943V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 2.6 | 10.3 | 25 |
| BRCA | Breast invasive carcinoma | 976 | 10.3 | 12.1 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 3.7 | 0 |
| COAD | Colon adenocarcinoma | 367 | 10.3 | 5.6 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 2.8 | 0 |
| GBM | Glioblastoma multiforme | 283 | 2.6 | 0.9 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 5.1 | 6.5 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 5.1 | 2.8 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 2.6 | 1.9 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2.8 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 5.1 | 4.7 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 7.7 | 6.5 | 25 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 0 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2.6 | 2.8 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0.9 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.8 | 0 |
| READ | Rectum adenocarcinoma | 122 | 2.6 | 1.9 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.9 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 15.4 | 2.8 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 7.7 | 7.5 | 25 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 20.5 | 18.7 | 25 |