Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | E23K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R361Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V175M | Missense | 1 |
| BRCA | Breast invasive carcinoma | I369N | Missense | 1 |
| BRCA | Breast invasive carcinoma | K289K | Silent | 1 |
| BRCA | Breast invasive carcinoma | L155V | Missense | 1 |
| BRCA | Breast invasive carcinoma | T311M | Missense | 1 |
| CESC | Cervical and endocervical cancers | V57G | Missense | 1 |
| COAD | Colon adenocarcinoma | C102R | Missense | 1 |
| COAD | Colon adenocarcinoma | E23* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | F169C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A32A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G324R | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | D29H | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A74G | Missense | 1 |
| LUAD | Lung adenocarcinoma | M40V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E245* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | E66E | Silent | 1 |
| PRAD | Prostate adenocarcinoma | A144G | Missense | 1 |
| PRAD | Prostate adenocarcinoma | Q236R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E238K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F208F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H143Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P273S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P332Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V261V | Silent | 1 |
| STAD | Stomach adenocarcinoma | G86G | Silent | 1 |
| STAD | Stomach adenocarcinoma | T311M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V376A | Missense | 1 |
| STAD | Stomach adenocarcinoma | W141* | Nonsense | 1 |
| TGCT | Testicular Germ Cell Tumors | T338K | Missense | 1 |
| THCA | Thyroid carcinoma | H334Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R223W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T349T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y174Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 12.5 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 12.5 | 12.5 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 4.2 | 0 |
| COAD | Colon adenocarcinoma | 367 | 0 | 8.3 | 33.3 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 12.5 | 4.2 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 4.2 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 4.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 4.2 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 0 | 33.3 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 12.5 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 8.3 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 25 | 16.7 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 12.5 | 8.3 | 33.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 4.2 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 4.2 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 25 | 4.2 | 0 |