Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | M20I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V140V | Silent | 1 |
| BRCA | Breast invasive carcinoma | K155K | Silent | 1 |
| COAD | Colon adenocarcinoma | A129V | Missense | 1 |
| COAD | Colon adenocarcinoma | E117K | Missense | 1 |
| COAD | Colon adenocarcinoma | Y66C | Missense | 1 |
| ESCA | Esophageal carcinoma | D160V | Missense | 1 |
| ESCA | Esophageal carcinoma | G131D | Missense | 1 |
| GBM | Glioblastoma multiforme | L162L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R3Q | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | G205S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | T225S | Missense | 1 |
| LAML | Acute Myeloid Leukemia | E188E | Silent | 1 |
| LUAD | Lung adenocarcinoma | E203* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | G121V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G59C | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q7Q | Silent | 1 |
| LUAD | Lung adenocarcinoma | R208Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A129S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E176K | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S98Y | Missense | 1 |
| PRAD | Prostate adenocarcinoma | E117G | Missense | 1 |
| READ | Rectum adenocarcinoma | Y66H | Missense | 1 |
| SARC | Sarcoma | P65S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P60S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S103Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V109V | Silent | 1 |
| STAD | Stomach adenocarcinoma | E54K | Missense | 1 |
| STAD | Stomach adenocarcinoma | P114Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y66Y | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A153A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A153V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E67K | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 12.5 | 4.2 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 12.5 | 0 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 0 | 12.5 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 8.3 | 0 |
| GBM | Glioblastoma multiforme | 283 | 12.5 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 4.2 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 8.3 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 12.5 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 12.5 | 12.5 | 100 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 8.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 4.2 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 4.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 4.2 | 0 |
| SARC | Sarcoma | 247 | 0 | 4.2 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 12.5 | 8.3 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 12.5 | 8.3 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 12.5 | 8.3 | 0 |