Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| PRAD | Prostate adenocarcinoma | G338G | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | A269A | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | A385T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E219D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E366Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G415R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L5L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q243Q | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q444H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R114H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V480A | Missense | 1 |
| BRCA | Breast invasive carcinoma | H126Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | K120N | Missense | 1 |
| BRCA | Breast invasive carcinoma | R229Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | Y218C | Missense | 1 |
| COAD | Colon adenocarcinoma | E390G | Missense | 1 |
| COAD | Colon adenocarcinoma | E66G | Missense | 1 |
| COAD | Colon adenocarcinoma | G207G | Silent | 1 |
| COAD | Colon adenocarcinoma | G31G | Silent | 1 |
| COAD | Colon adenocarcinoma | K155K | Silent | 1 |
| COAD | Colon adenocarcinoma | M154T | Missense | 1 |
| COAD | Colon adenocarcinoma | P447P | Silent | 1 |
| COAD | Colon adenocarcinoma | Q211Q | Silent | 1 |
| COAD | Colon adenocarcinoma | Q250R | Missense | 1 |
| COAD | Colon adenocarcinoma | R131L | Missense | 1 |
| COAD | Colon adenocarcinoma | R131W | Missense | 1 |
| COAD | Colon adenocarcinoma | R168R | Silent | 1 |
| COAD | Colon adenocarcinoma | R229* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R229R | Silent | 1 |
| COAD | Colon adenocarcinoma | R278Q | Missense | 1 |
| COAD | Colon adenocarcinoma | S287S | Silent | 1 |
| COAD | Colon adenocarcinoma | S388N | Missense | 1 |
| COAD | Colon adenocarcinoma | T537T | Silent | 1 |
| COAD | Colon adenocarcinoma | W165R | Missense | 1 |
| ESCA | Esophageal carcinoma | L312L | Silent | 1 |
| ESCA | Esophageal carcinoma | S249* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | T485A | Missense | 1 |
| GBM | Glioblastoma multiforme | L536F | Missense | 1 |
| GBM | Glioblastoma multiforme | R131L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G417G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T156T | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T178T | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T547S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V104V | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V264I | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L530P | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Q561* | Nonsense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | T425P | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R271W | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L254Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L38P | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N237S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R171* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | R244G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R263G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S210T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S352F | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V351V | Silent | 1 |
| LUAD | Lung adenocarcinoma | G355C | Missense | 1 |
| LUAD | Lung adenocarcinoma | P416T | Missense | 1 |
| LUAD | Lung adenocarcinoma | R159L | Missense | 1 |
| LUAD | Lung adenocarcinoma | T564T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | M405L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P94H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R272S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S337S | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | S574N | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | T539A | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P461P | Silent | 1 |
| PRAD | Prostate adenocarcinoma | P568L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | T10M | Missense | 1 |
| READ | Rectum adenocarcinoma | N127S | Missense | 1 |
| READ | Rectum adenocarcinoma | R229R | Silent | 1 |
| READ | Rectum adenocarcinoma | V133M | Missense | 1 |
| SARC | Sarcoma | D75N | Missense | 1 |
| SARC | Sarcoma | R271L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A116A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A160D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D76N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D80G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E227K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E234E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E234K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E79K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G20G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G292E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G40E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K46K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L185L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L533L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | M154I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | N223N | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P340L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P347S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P475L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q182Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Q28* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R200Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S49S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T527T | Silent | 1 |
| STAD | Stomach adenocarcinoma | G338G | Silent | 1 |
| STAD | Stomach adenocarcinoma | S445R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A532T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D135N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E188D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R114C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R114H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R131Q | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 8.6 | 10.1 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 5.8 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 25.7 | 13 | 20 |
| ESCA | Esophageal carcinoma | 185 | 2.9 | 1.4 | 20 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.9 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 11.4 | 2.9 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.9 | 20 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1.4 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 2.9 | 10.1 | 20 |
| LUAD | Lung adenocarcinoma | 533 | 2.9 | 4.3 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2.9 | 1.4 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 8.6 | 2.9 | 0 |
| READ | Rectum adenocarcinoma | 122 | 2.9 | 2.9 | 0 |
| SARC | Sarcoma | 247 | 0 | 2.9 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 28.6 | 18.8 | 20 |
| STAD | Stomach adenocarcinoma | 393 | 2.9 | 1.4 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 8.7 | 0 |