Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| LAML | Acute Myeloid Leukemia | R140Q | Missense | 16 |
| LGG | Brain Lower Grade Glioma | R172K | Missense | 12 |
| COAD | Colon adenocarcinoma | R140L | Missense | 3 |
| LAML | Acute Myeloid Leukemia | R172K | Missense | 3 |
| LGG | Brain Lower Grade Glioma | R172M | Missense | 3 |
| LGG | Brain Lower Grade Glioma | R172G | Missense | 2 |
| LGG | Brain Lower Grade Glioma | R172W | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | G137E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K251K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | M411I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V111V | Silent | 1 |
| COAD | Colon adenocarcinoma | A416V | Missense | 1 |
| COAD | Colon adenocarcinoma | A47V | Missense | 1 |
| COAD | Colon adenocarcinoma | D187V | Missense | 1 |
| COAD | Colon adenocarcinoma | D277N | Missense | 1 |
| COAD | Colon adenocarcinoma | G171D | Missense | 1 |
| COAD | Colon adenocarcinoma | G171G | Silent | 1 |
| COAD | Colon adenocarcinoma | I441T | Missense | 1 |
| COAD | Colon adenocarcinoma | P158L | Missense | 1 |
| COAD | Colon adenocarcinoma | P158P | Silent | 1 |
| COAD | Colon adenocarcinoma | P158S | Missense | 1 |
| COAD | Colon adenocarcinoma | R140W | Missense | 1 |
| COAD | Colon adenocarcinoma | R172R | Silent | 1 |
| COAD | Colon adenocarcinoma | R172S | Missense | 1 |
| COAD | Colon adenocarcinoma | S317* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | T331M | Missense | 1 |
| ESCA | Esophageal carcinoma | G220D | Missense | 1 |
| ESCA | Esophageal carcinoma | G417V | Missense | 1 |
| ESCA | Esophageal carcinoma | R140Q | Missense | 1 |
| ESCA | Esophageal carcinoma | R60H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E68E | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R140Q | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | A214V | Missense | 1 |
| LAML | Acute Myeloid Leukemia | R140L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R172S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I419T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R172K | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R172S | Missense | 1 |
| LUAD | Lung adenocarcinoma | W63* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | A239V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | G201D | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | K133R | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L143M | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R288L | Missense | 1 |
| READ | Rectum adenocarcinoma | P158P | Silent | 1 |
| READ | Rectum adenocarcinoma | P158Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G137E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | M248I | Missense | 1 |
| STAD | Stomach adenocarcinoma | W375* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A370T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C402C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D83V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E268D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I228L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K413K | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R159H | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 22.2 | 2.6 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 0 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 33.3 | 17.9 | 33.3 |
| ESCA | Esophageal carcinoma | 185 | 0 | 5.1 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 11.1 | 1.3 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.3 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 25.6 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 25.6 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 3.8 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 0 | 33.3 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 0 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 6.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 11.1 | 1.3 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 0 | 2.6 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 0 | 33.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 22.2 | 6.4 | 0 |