Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| UCEC | Uterine Corpus Endometrial Carcinoma | R339* | Nonsense | 3 |
| COAD | Colon adenocarcinoma | R339* | Nonsense | 2 |
| STAD | Stomach adenocarcinoma | R339* | Nonsense | 2 |
| BLCA | Bladder urothelial carcinoma | F135F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L130L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R51Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | A315S | Missense | 1 |
| BRCA | Breast invasive carcinoma | E226Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | E230K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E402E | Silent | 1 |
| BRCA | Breast invasive carcinoma | G50V | Missense | 1 |
| BRCA | Breast invasive carcinoma | L130L | Silent | 1 |
| BRCA | Breast invasive carcinoma | P288P | Silent | 1 |
| CESC | Cervical and endocervical cancers | Q296* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | R14Q | Missense | 1 |
| COAD | Colon adenocarcinoma | A305T | Missense | 1 |
| COAD | Colon adenocarcinoma | D312N | Missense | 1 |
| COAD | Colon adenocarcinoma | D370Y | Missense | 1 |
| COAD | Colon adenocarcinoma | E377K | Missense | 1 |
| COAD | Colon adenocarcinoma | K398* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | N55K | Missense | 1 |
| COAD | Colon adenocarcinoma | S362S | Silent | 1 |
| COAD | Colon adenocarcinoma | W378R | Missense | 1 |
| ESCA | Esophageal carcinoma | R339* | Nonsense | 1 |
| GBM | Glioblastoma multiforme | A220V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L411R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R203R | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S202S | Silent | 1 |
| LGG | Brain Lower Grade Glioma | R339* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | E303K | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K287R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R110L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V4V | Silent | 1 |
| LUAD | Lung adenocarcinoma | A220S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A335A | Silent | 1 |
| LUAD | Lung adenocarcinoma | F3F | Silent | 1 |
| LUAD | Lung adenocarcinoma | G228S | Missense | 1 |
| LUAD | Lung adenocarcinoma | G43V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G43W | Missense | 1 |
| LUAD | Lung adenocarcinoma | N244K | Missense | 1 |
| LUAD | Lung adenocarcinoma | P186P | Silent | 1 |
| LUAD | Lung adenocarcinoma | P353P | Silent | 1 |
| LUAD | Lung adenocarcinoma | R107L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G136W | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | W378C | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | P89H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G136W | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R247W | Missense | 1 |
| READ | Rectum adenocarcinoma | R339* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | W378R | Missense | 1 |
| SARC | Sarcoma | V235V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I234I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P11S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P97S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S10S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S77F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S78S | Silent | 1 |
| STAD | Stomach adenocarcinoma | A305V | Missense | 1 |
| STAD | Stomach adenocarcinoma | C358Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | D312D | Silent | 1 |
| STAD | Stomach adenocarcinoma | G29D | Missense | 1 |
| STAD | Stomach adenocarcinoma | G314G | Silent | 1 |
| STAD | Stomach adenocarcinoma | G67G | Silent | 1 |
| STAD | Stomach adenocarcinoma | R245H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R339R | Silent | 1 |
| THCA | Thyroid carcinoma | D53Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A258A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A315T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C369C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D370Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E352* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E352K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E373* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G314D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R245H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V235M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | W378* | Nonsense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 8.7 | 2.3 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 13 | 9.3 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.3 | 6.7 |
| COAD | Colon adenocarcinoma | 367 | 4.3 | 14 | 20 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 6.7 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.3 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 8.7 | 2.3 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 6.7 |
| LIHC | Liver hepatocellular carcinoma | 373 | 4.3 | 7 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 17.4 | 14 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 2.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.3 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.3 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 4.7 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.3 | 6.7 |
| SARC | Sarcoma | 247 | 4.3 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 13 | 7 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 17.4 | 9.3 | 13.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 2.3 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 8.7 | 14 | 40 |