Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | E159K | Missense | 2 |
| COAD | Colon adenocarcinoma | W253* | Nonsense | 2 |
| BLCA | Bladder urothelial carcinoma | D75N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K80E | Missense | 1 |
| BRCA | Breast invasive carcinoma | S201L | Missense | 1 |
| COAD | Colon adenocarcinoma | G227R | Missense | 1 |
| COAD | Colon adenocarcinoma | S149P | Missense | 1 |
| COAD | Colon adenocarcinoma | W253C | Missense | 1 |
| ESCA | Esophageal carcinoma | T59M | Missense | 1 |
| GBM | Glioblastoma multiforme | E68K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | W253C | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R44G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T157A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E204Q | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | W253C | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R154M | Missense | 1 |
| READ | Rectum adenocarcinoma | E68K | Missense | 1 |
| SARC | Sarcoma | E109K | Missense | 1 |
| SARC | Sarcoma | K61K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I103I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P249S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R114W | Missense | 1 |
| STAD | Stomach adenocarcinoma | G260* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | L82P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A89V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E109* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P202L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y254H | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 16.7 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 4.2 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 0 | 12.5 | 50 |
| ESCA | Esophageal carcinoma | 185 | 0 | 4.2 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 4.2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 4.2 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 8.3 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 0 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.2 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 4.2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 4.2 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 4.2 | 0 |
| SARC | Sarcoma | 247 | 50 | 4.2 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 50 | 8.3 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 4.2 | 25 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 12.5 | 25 |