Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| STAD | Stomach adenocarcinoma | R6Q | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | C225C | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | D633D | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | E412K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E781E | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R393C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R480G | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S269R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y405Y | Silent | 1 |
| BRCA | Breast invasive carcinoma | A383T | Missense | 1 |
| BRCA | Breast invasive carcinoma | D425N | Missense | 1 |
| BRCA | Breast invasive carcinoma | E173G | Missense | 1 |
| BRCA | Breast invasive carcinoma | E190G | Missense | 1 |
| BRCA | Breast invasive carcinoma | E284Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | R489R | Silent | 1 |
| CESC | Cervical and endocervical cancers | E490D | Missense | 1 |
| CESC | Cervical and endocervical cancers | E781D | Missense | 1 |
| CESC | Cervical and endocervical cancers | S28* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | A93V | Missense | 1 |
| COAD | Colon adenocarcinoma | C202C | Silent | 1 |
| COAD | Colon adenocarcinoma | D138G | Missense | 1 |
| COAD | Colon adenocarcinoma | D197D | Silent | 1 |
| COAD | Colon adenocarcinoma | D197N | Missense | 1 |
| COAD | Colon adenocarcinoma | D570N | Missense | 1 |
| COAD | Colon adenocarcinoma | G319C | Missense | 1 |
| COAD | Colon adenocarcinoma | R465H | Missense | 1 |
| COAD | Colon adenocarcinoma | R517* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R625Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R693H | Missense | 1 |
| ESCA | Esophageal carcinoma | A114A | Silent | 1 |
| ESCA | Esophageal carcinoma | A263S | Missense | 1 |
| ESCA | Esophageal carcinoma | G813V | Missense | 1 |
| ESCA | Esophageal carcinoma | R54Q | Missense | 1 |
| ESCA | Esophageal carcinoma | S39S | Silent | 1 |
| GBM | Glioblastoma multiforme | R393C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L106F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M182V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R346W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V285V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | G571A | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P92P | Silent | 1 |
| LGG | Brain Lower Grade Glioma | S803S | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | P652S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q441L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S28* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E153* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | K4K | Silent | 1 |
| LUAD | Lung adenocarcinoma | P113S | Missense | 1 |
| LUAD | Lung adenocarcinoma | R29R | Silent | 1 |
| LUAD | Lung adenocarcinoma | R480G | Missense | 1 |
| LUAD | Lung adenocarcinoma | T642I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V330I | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | E198K | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | G134C | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | E727K | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | S117F | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A668T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | E198K | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G658G | Silent | 1 |
| READ | Rectum adenocarcinoma | A22A | Silent | 1 |
| READ | Rectum adenocarcinoma | G288S | Missense | 1 |
| SARC | Sarcoma | K747K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A495V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K671K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L106L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P107S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P118S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P606L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q500* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R639Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S26S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V760L | Missense | 1 |
| STAD | Stomach adenocarcinoma | A646T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A771V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D657D | Silent | 1 |
| STAD | Stomach adenocarcinoma | G706R | Missense | 1 |
| STAD | Stomach adenocarcinoma | G812G | Silent | 1 |
| STAD | Stomach adenocarcinoma | N481H | Missense | 1 |
| STAD | Stomach adenocarcinoma | P722S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R641C | Missense | 1 |
| STAD | Stomach adenocarcinoma | S26S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T245M | Missense | 1 |
| STAD | Stomach adenocarcinoma | T663M | Missense | 1 |
| STAD | Stomach adenocarcinoma | W594* | Nonsense | 1 |
| TGCT | Testicular Germ Cell Tumors | Q583* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D79E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E46K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L563M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P377P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P71P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q456Q | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R159G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R260* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R489R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R768M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S277R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S31A | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 14.8 | 6.3 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 3.7 | 7.9 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 3.2 | 12.5 |
| COAD | Colon adenocarcinoma | 367 | 7.4 | 12.7 | 12.5 |
| ESCA | Esophageal carcinoma | 185 | 7.4 | 4.8 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.6 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.7 | 4.8 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 3.7 | 1.6 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 3.7 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 3.2 | 12.5 |
| LUAD | Lung adenocarcinoma | 533 | 7.4 | 4.8 | 12.5 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 1.6 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 3.2 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 3.2 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 3.7 | 3.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 3.7 | 1.6 | 0 |
| SARC | Sarcoma | 247 | 3.7 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 11.1 | 9.5 | 12.5 |
| STAD | Stomach adenocarcinoma | 393 | 11.1 | 15.9 | 12.5 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 12.5 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 14.8 | 11.1 | 12.5 |