Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | E454K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E462* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | L317F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V135L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V458L | Missense | 1 |
| BRCA | Breast invasive carcinoma | C220C | Silent | 1 |
| BRCA | Breast invasive carcinoma | E493D | Missense | 1 |
| BRCA | Breast invasive carcinoma | L105V | Missense | 1 |
| BRCA | Breast invasive carcinoma | P304P | Silent | 1 |
| BRCA | Breast invasive carcinoma | S572C | Missense | 1 |
| BRCA | Breast invasive carcinoma | V163G | Missense | 1 |
| CESC | Cervical and endocervical cancers | G766S | Missense | 1 |
| CESC | Cervical and endocervical cancers | L773L | Silent | 1 |
| CESC | Cervical and endocervical cancers | T319M | Missense | 1 |
| COAD | Colon adenocarcinoma | G702G | Silent | 1 |
| COAD | Colon adenocarcinoma | R307W | Missense | 1 |
| ESCA | Esophageal carcinoma | C206C | Silent | 1 |
| ESCA | Esophageal carcinoma | G192W | Missense | 1 |
| ESCA | Esophageal carcinoma | P626P | Silent | 1 |
| ESCA | Esophageal carcinoma | Q510* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | Y66* | Nonsense | 1 |
| GBM | Glioblastoma multiforme | Q762H | Missense | 1 |
| GBM | Glioblastoma multiforme | V104I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | C223F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D164N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E130K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E493Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I49M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M488I | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | K656Q | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L193L | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | R207W | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V411V | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P296A | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T121A | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V201M | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K2K | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | L151P | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L235F | Missense | 1 |
| LUAD | Lung adenocarcinoma | A397T | Missense | 1 |
| LUAD | Lung adenocarcinoma | E772Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | G353V | Missense | 1 |
| LUAD | Lung adenocarcinoma | K316N | Missense | 1 |
| LUAD | Lung adenocarcinoma | K32E | Missense | 1 |
| LUAD | Lung adenocarcinoma | N443S | Missense | 1 |
| LUAD | Lung adenocarcinoma | S301S | Silent | 1 |
| LUAD | Lung adenocarcinoma | S570R | Missense | 1 |
| LUAD | Lung adenocarcinoma | S628S | Silent | 1 |
| LUAD | Lung adenocarcinoma | T719T | Silent | 1 |
| LUAD | Lung adenocarcinoma | V336F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A333S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | H818N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | K261N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S569I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | T525K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | W274C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R401Q | Missense | 1 |
| PRAD | Prostate adenocarcinoma | V225I | Missense | 1 |
| READ | Rectum adenocarcinoma | M686I | Missense | 1 |
| READ | Rectum adenocarcinoma | R401W | Missense | 1 |
| READ | Rectum adenocarcinoma | R538I | Missense | 1 |
| READ | Rectum adenocarcinoma | R754Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D47N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E451E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E517K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K32Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | N184N | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Q398Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R790R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S409F | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q459* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R108* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R468* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R754Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R823M | Missense | 1 |
| STAD | Stomach adenocarcinoma | T348I | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | S64I | Missense | 1 |
| THCA | Thyroid carcinoma | L317L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A41S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C179R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E15K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E355K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E75K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F219L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G702S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K53T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P448H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R412* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R604H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S386S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S592L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T319M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V677A | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 5.9 | 14.3 |
| BRCA | Breast invasive carcinoma | 976 | 11.1 | 5.9 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 5.6 | 2.9 | 0 |
| COAD | Colon adenocarcinoma | 367 | 5.6 | 1.5 | 0 |
| ESCA | Esophageal carcinoma | 185 | 11.1 | 1.5 | 28.6 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.9 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 8.8 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 11.1 | 2.9 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.5 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2.9 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 5.6 | 2.9 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 16.7 | 11.8 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 8.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.9 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 5.9 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 22.2 | 5.9 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 4.4 | 42.9 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.5 | 0 |
| THCA | Thyroid carcinoma | 495 | 5.6 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 5.6 | 19.1 | 14.3 |