Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | S203L | Missense | 2 |
| COAD | Colon adenocarcinoma | R596W | Missense | 2 |
| COAD | Colon adenocarcinoma | T343T | Silent | 2 |
| LIHC | Liver hepatocellular carcinoma | L903Q | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E598K | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F754F | Silent | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S886L | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D1121N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E993Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G1022W | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K452K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L892F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R1137R | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R478K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R999S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1243L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S417L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S75* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | T154I | Missense | 1 |
| BRCA | Breast invasive carcinoma | L906L | Silent | 1 |
| BRCA | Breast invasive carcinoma | P367R | Missense | 1 |
| BRCA | Breast invasive carcinoma | R425Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | S24L | Missense | 1 |
| CESC | Cervical and endocervical cancers | C1161C | Silent | 1 |
| CESC | Cervical and endocervical cancers | E184K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E468K | Missense | 1 |
| CESC | Cervical and endocervical cancers | F584F | Silent | 1 |
| CESC | Cervical and endocervical cancers | G667S | Missense | 1 |
| CESC | Cervical and endocervical cancers | H864Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | N958S | Missense | 1 |
| CESC | Cervical and endocervical cancers | T127I | Missense | 1 |
| COAD | Colon adenocarcinoma | A396A | Silent | 1 |
| COAD | Colon adenocarcinoma | E245* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | E245G | Missense | 1 |
| COAD | Colon adenocarcinoma | E800G | Missense | 1 |
| COAD | Colon adenocarcinoma | G763G | Silent | 1 |
| COAD | Colon adenocarcinoma | H998R | Missense | 1 |
| COAD | Colon adenocarcinoma | I1189M | Missense | 1 |
| COAD | Colon adenocarcinoma | K240Q | Missense | 1 |
| COAD | Colon adenocarcinoma | L674F | Missense | 1 |
| COAD | Colon adenocarcinoma | P499P | Silent | 1 |
| COAD | Colon adenocarcinoma | R1096H | Missense | 1 |
| COAD | Colon adenocarcinoma | R1221C | Missense | 1 |
| COAD | Colon adenocarcinoma | R578C | Missense | 1 |
| COAD | Colon adenocarcinoma | S279S | Silent | 1 |
| COAD | Colon adenocarcinoma | S539S | Silent | 1 |
| COAD | Colon adenocarcinoma | S86S | Silent | 1 |
| COAD | Colon adenocarcinoma | S986P | Missense | 1 |
| COAD | Colon adenocarcinoma | V1193I | Missense | 1 |
| ESCA | Esophageal carcinoma | A542S | Missense | 1 |
| ESCA | Esophageal carcinoma | G1198D | Missense | 1 |
| ESCA | Esophageal carcinoma | G471V | Missense | 1 |
| ESCA | Esophageal carcinoma | K217N | Missense | 1 |
| ESCA | Esophageal carcinoma | R1049C | Missense | 1 |
| ESCA | Esophageal carcinoma | R1050H | Missense | 1 |
| ESCA | Esophageal carcinoma | R1096H | Missense | 1 |
| ESCA | Esophageal carcinoma | R262W | Missense | 1 |
| GBM | Glioblastoma multiforme | A842S | Missense | 1 |
| GBM | Glioblastoma multiforme | P1229P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D803N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E495Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E556V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H448R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L1180F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P1012L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R428Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R930G | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S208S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S521C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S75L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T159P | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T741T | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | K385N | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | T1134K | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L1132L | Silent | 1 |
| LGG | Brain Lower Grade Glioma | A280V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E720* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | I21S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I614I | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | K196Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K461E | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R688G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S148C | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T192S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A1102D | Missense | 1 |
| LUAD | Lung adenocarcinoma | A168A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A168S | Missense | 1 |
| LUAD | Lung adenocarcinoma | D189H | Missense | 1 |
| LUAD | Lung adenocarcinoma | D94H | Missense | 1 |
| LUAD | Lung adenocarcinoma | D962N | Missense | 1 |
| LUAD | Lung adenocarcinoma | E726D | Missense | 1 |
| LUAD | Lung adenocarcinoma | K151N | Missense | 1 |
| LUAD | Lung adenocarcinoma | K240I | Missense | 1 |
| LUAD | Lung adenocarcinoma | L481L | Silent | 1 |
| LUAD | Lung adenocarcinoma | N743I | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q119L | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q264L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1176Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | R496K | Missense | 1 |
| LUAD | Lung adenocarcinoma | R596L | Missense | 1 |
| LUAD | Lung adenocarcinoma | V723L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A463A | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L393L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | P878P | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | R1176Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R501Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R693Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V1169L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | E245* | Nonsense | 1 |
| OV | Ovarian serous cystadenocarcinoma | I557S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S986Y | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A542A | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | A74S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S172I | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S901F | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | G667D | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A403T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | L990L | Silent | 1 |
| PRAD | Prostate adenocarcinoma | S532S | Silent | 1 |
| READ | Rectum adenocarcinoma | A690D | Missense | 1 |
| READ | Rectum adenocarcinoma | C836S | Missense | 1 |
| READ | Rectum adenocarcinoma | F754L | Missense | 1 |
| READ | Rectum adenocarcinoma | I574I | Silent | 1 |
| READ | Rectum adenocarcinoma | R164* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | R300W | Missense | 1 |
| SARC | Sarcoma | A579S | Missense | 1 |
| SARC | Sarcoma | K486R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A765A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D19V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D359H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E1156K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E477K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E956K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E961K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H811Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L62F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L730L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1126L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P210T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P248L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P536L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P591L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P593L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P915S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R164* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R233Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R498W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S392F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S399S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S43F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T1080T | Silent | 1 |
| STAD | Stomach adenocarcinoma | A346D | Missense | 1 |
| STAD | Stomach adenocarcinoma | A450V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A829V | Missense | 1 |
| STAD | Stomach adenocarcinoma | C1020C | Silent | 1 |
| STAD | Stomach adenocarcinoma | C1197C | Silent | 1 |
| STAD | Stomach adenocarcinoma | D66G | Missense | 1 |
| STAD | Stomach adenocarcinoma | G805G | Silent | 1 |
| STAD | Stomach adenocarcinoma | H534Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | L906L | Silent | 1 |
| STAD | Stomach adenocarcinoma | M1058V | Missense | 1 |
| STAD | Stomach adenocarcinoma | P1230S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P135A | Missense | 1 |
| STAD | Stomach adenocarcinoma | P248P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P490L | Missense | 1 |
| STAD | Stomach adenocarcinoma | P490P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P736T | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q1003K | Missense | 1 |
| STAD | Stomach adenocarcinoma | R425W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R478R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R619Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R693W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R733C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R733H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S1245P | Missense | 1 |
| STAD | Stomach adenocarcinoma | S526T | Missense | 1 |
| STAD | Stomach adenocarcinoma | S576L | Missense | 1 |
| STAD | Stomach adenocarcinoma | S772S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S90P | Missense | 1 |
| STAD | Stomach adenocarcinoma | T1028T | Silent | 1 |
| STAD | Stomach adenocarcinoma | T508T | Silent | 1 |
| STAD | Stomach adenocarcinoma | V1009I | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y704H | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y815C | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | D654N | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | G54E | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | R501W | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | V608I | Missense | 1 |
| THCA | Thyroid carcinoma | S1107S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1120T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A246T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A49A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C1020Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F923S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G874D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H888H | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I952I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L697L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q47H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1221C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R164* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1014F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S519S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S576L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V185F | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 4.1 | 7.1 | 14.3 |
| BRCA | Breast invasive carcinoma | 976 | 2 | 1.9 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 4.1 | 3.8 | 0 |
| COAD | Colon adenocarcinoma | 367 | 16.3 | 8.3 | 14.3 |
| ESCA | Esophageal carcinoma | 185 | 0 | 5.1 | 0 |
| GBM | Glioblastoma multiforme | 283 | 2 | 0.6 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 4.1 | 7.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.3 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 2 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1.3 | 14.3 |
| LIHC | Liver hepatocellular carcinoma | 373 | 2 | 4.5 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 4.1 | 9.6 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 6.1 | 2.6 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.3 | 14.3 |
| PAAD | Pancreatic adenocarcinoma | 126 | 2 | 1.9 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0.6 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 4.1 | 0.6 | 0 |
| READ | Rectum adenocarcinoma | 122 | 2 | 2.6 | 14.3 |
| SARC | Sarcoma | 247 | 0 | 1.3 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 8.2 | 12.2 | 14.3 |
| STAD | Stomach adenocarcinoma | 393 | 20.4 | 14.7 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 2.6 | 0 |
| THCA | Thyroid carcinoma | 495 | 2 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 14.3 | 9 | 14.3 |