Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | R62L | Missense | 2 |
| COAD | Colon adenocarcinoma | R62W | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D127H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D392D | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | E11Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E251Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L217L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L37L | Silent | 1 |
| BRCA | Breast invasive carcinoma | F252I | Missense | 1 |
| BRCA | Breast invasive carcinoma | I315S | Missense | 1 |
| CESC | Cervical and endocervical cancers | E119K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E11K | Missense | 1 |
| CESC | Cervical and endocervical cancers | R222Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R242W | Missense | 1 |
| COAD | Colon adenocarcinoma | R62Q | Missense | 1 |
| COAD | Colon adenocarcinoma | S80Y | Missense | 1 |
| COAD | Colon adenocarcinoma | T379M | Missense | 1 |
| ESCA | Esophageal carcinoma | E366Q | Missense | 1 |
| ESCA | Esophageal carcinoma | H273N | Missense | 1 |
| GBM | Glioblastoma multiforme | L160P | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L217L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R95G | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S109L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | D189A | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | H187N | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | N237K | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S343S | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | T370A | Missense | 1 |
| LGG | Brain Lower Grade Glioma | D345N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R399C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S5G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A49V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I338V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N2T | Missense | 1 |
| LUAD | Lung adenocarcinoma | E103K | Missense | 1 |
| LUAD | Lung adenocarcinoma | L217L | Silent | 1 |
| LUAD | Lung adenocarcinoma | P180P | Silent | 1 |
| LUAD | Lung adenocarcinoma | R168L | Missense | 1 |
| LUAD | Lung adenocarcinoma | T389S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G304G | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | W271C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R62L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L191L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P254L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P268S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T184T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T221T | Silent | 1 |
| STAD | Stomach adenocarcinoma | D230D | Silent | 1 |
| STAD | Stomach adenocarcinoma | H372R | Missense | 1 |
| STAD | Stomach adenocarcinoma | R399C | Missense | 1 |
| STAD | Stomach adenocarcinoma | T124A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A75V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D392D | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G183E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P129L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | W196C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 23.1 | 6.7 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 4.4 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 6.7 | 0 |
| COAD | Colon adenocarcinoma | 367 | 0 | 17.8 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 4.4 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 7.7 | 4.4 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 7.7 | 6.7 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.2 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 6.7 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 6.7 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 15.4 | 6.7 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 7.7 | 2.2 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 23.1 | 4.4 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 7.7 | 6.7 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 7.7 | 8.9 | 0 |