Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | F337F | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | E168Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E600D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G832A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K635N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L360L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q252H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R392Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R783Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R785C | Missense | 1 |
| BRCA | Breast invasive carcinoma | H157H | Silent | 1 |
| BRCA | Breast invasive carcinoma | I406V | Missense | 1 |
| BRCA | Breast invasive carcinoma | I674I | Silent | 1 |
| BRCA | Breast invasive carcinoma | R799Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | E767K | Missense | 1 |
| CESC | Cervical and endocervical cancers | Q281* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | S481L | Missense | 1 |
| COAD | Colon adenocarcinoma | G699G | Silent | 1 |
| COAD | Colon adenocarcinoma | H593L | Missense | 1 |
| COAD | Colon adenocarcinoma | L436F | Missense | 1 |
| COAD | Colon adenocarcinoma | R449C | Missense | 1 |
| COAD | Colon adenocarcinoma | R533H | Missense | 1 |
| COAD | Colon adenocarcinoma | R681H | Missense | 1 |
| COAD | Colon adenocarcinoma | R805R | Silent | 1 |
| ESCA | Esophageal carcinoma | G561S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D615N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K511K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L173L | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | A552S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P455A | Missense | 1 |
| LGG | Brain Lower Grade Glioma | L517L | Silent | 1 |
| LGG | Brain Lower Grade Glioma | S636I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P704H | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R515W | Missense | 1 |
| LUAD | Lung adenocarcinoma | A614V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G414C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G425W | Missense | 1 |
| LUAD | Lung adenocarcinoma | K536M | Missense | 1 |
| LUAD | Lung adenocarcinoma | L106L | Silent | 1 |
| LUAD | Lung adenocarcinoma | M595I | Missense | 1 |
| LUAD | Lung adenocarcinoma | R310R | Silent | 1 |
| LUAD | Lung adenocarcinoma | R805H | Missense | 1 |
| LUAD | Lung adenocarcinoma | V328I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V543I | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L608F | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R658H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S304I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | E813K | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R133H | Missense | 1 |
| SARC | Sarcoma | G56D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E347K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I539I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I667I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P248L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S361S | Silent | 1 |
| STAD | Stomach adenocarcinoma | D178V | Missense | 1 |
| STAD | Stomach adenocarcinoma | E443K | Missense | 1 |
| STAD | Stomach adenocarcinoma | N656K | Missense | 1 |
| STAD | Stomach adenocarcinoma | N808S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P153P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P430L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R323W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R491H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R701R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R805R | Silent | 1 |
| THCA | Thyroid carcinoma | G505S | Missense | 1 |
| THCA | Thyroid carcinoma | Y311Y | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A399A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A485A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A618T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A750V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R251R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R496C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S481L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S665P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T509T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T582N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V526A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y645Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 4.2 | 14.5 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 8.3 | 3.6 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 3.6 | 100 |
| COAD | Colon adenocarcinoma | 367 | 8.3 | 9.1 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 1.8 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 8.3 | 1.8 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.8 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.8 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 4.2 | 1.8 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 3.6 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 8.3 | 12.7 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 1.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 5.5 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 3.6 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.8 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 20.8 | 3.6 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 12.5 | 12.7 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 4.2 | 1.8 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 20.8 | 12.7 | 0 |